Some medical impressions of India, with particular reference to diabetes mellitus and cardiovascular disease

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Clinical trial of a new sulphonylurea in maturity-onset diabetes-hb419 (Glibenclamide)

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Diabetes mellitus in the urbanized Johannesburg African

Diabetes mellitu is a common and important clinical problem in the urbanized Johannesburg African. A survey of Africans aged 30 and over attending the Baragwanath Hospital Casualty Department showed an incidence of diabetes of about 1%.1 Yet, apart from Campbell's studies on the Zulu diabetic, a search of the literature yielded little of note on diabetes in the South African Bantu. We have therefore undertaken an analysis of the records of 250 new cases of diabetes mellitus in African subjects admitted to Baragwanath Hospital during the period 1951 - 1957. These cases were selected at random and constituted at least 75% of all the new African diabetics admitted during this period

Treatment of human tapeworm infections with Yomesan: Single dose treatment in non-fasting subjects

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Haemolytic anaemia, thrombocytopenia and uraemia in eclampsia

Haemolytic anaemia has long been known as a not infrequent complication of eclampsia. Thrombocytopenia may also be associated with eclampsia, while the simultaneous occurrence of both haematological complications has recently been reported by Pritchard et al As these haematological disturbances may have an important bearing on the patbogenesis and therapy of eclampsia, it is the purpose of this paper to draw attention to their occurrence and management, by presenting 2 cases in African patients in whom eclampsia was associated with acute intravascular haemolysis, thrombocytopenia, and uraemia

Asymptomatic bacteriuria in diabetes mellitus

A study was undertaken to determine the frequency of asymptomatic bacteriuria among 100 ambulant diabetic patients attending a diabetic outpatient clinic. At the same time, we assessed the reliability of the Uricult dip-slide method for detecting urinary bacterial growth. Significant bacteriuria occurred in 9% of the total diabetic group, largely attributable to the high prevalence in elderly diabetic women. Important characteristics of the affected diabetic patients included infection, commonly with Escherichia coli, frequently associated pyuria, good diabetic control with normal renal function and a high recurrence rate of bacteriuria after treatment. The dipslide method compared quite favourably with the laboratory culture method, but it failed to detect 2 out of 8 cases with significant bacteriuria.S. Afr. Med. J., 48, 1306 (1974)

IDIOPATHIC CARDIOMYOPATHY SIMULATING ORGANIC VALVE DISEASE

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VIRILIZATION CAUSED BY A LIPOID-CELL TUMOUR OF THE OVARY

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When to transfuse: Red blood cell and platelet transfusion thresholds in clinical practice

Blood component transfusion is a frequently prescribed intervention in healthcare that depends on the availability of a limited and expensive resource. The transfusion of blood products may be life-saving, but it is not without risk. Society guidelines and clinical trials guide transfusion decisions regarding transfusion thresholds, as well as the appropriateness of prophylactic v. therapeutic transfusion strategies. This review provides a practical and evidence-informed approach to the transfusion of red blood cells and platelets in commonly encountered clinical settings