55 research outputs found
Real-time Visualisation of Actin Filaments within Native and Tissue Engineered Cartilage using SiR-Actin
Click on the DOI link to access the article (may not be free).Astrocytes, the most abundant glial cells in the central nervous system, play a critical role in supporting the normal physiological function of neurons. Recent studies have revealed that astrocyte transplantation can promote axonal regeneration and functional recovery after spinal cord injury. Biomaterial can be designed as a growth-permissive substrate and serve as a carrier for astrocyte transplantation into injured spinal cord. In this study, we developed a method to generate collagen microspheres encapsulating astrocytes by injecting the mixture of collagen and astrocytes into the cell culture medium with a syringe controlled by a syringe pump
Modification of the Sheehan Knee arthroplasty for additional replacement of the femoropatellar articulation
Biomechanical considerations in the pathogenesis of osteoarthritis of the knee
Osteoarthritis is the most common joint disease and a major cause of disability. The knee is the large joint most affected. While chronological age is the single most important risk factor of osteoarthritis, the pathogenesis of knee osteoarthritis in the young patient is predominantly related to an unfavorable biomechanical environment at the joint. This results in mechanical demand that exceeds the ability of a joint to repair and maintain itself, predisposing the articular cartilage to premature degeneration. This review examines the available basic science, preclinical and clinical evidence regarding several such unfavorable biomechanical conditions about the knee: malalignment, loss of meniscal tissue, cartilage defects and joint instability or laxity
Meniscal Replacement With a Silk Fibroin Scaffold Reduces Contact Stresses in the Human Knee
Successful Treatment of Painful Irreparable Partial Meniscal Defects With a Polyurethane Scaffold
Molecular biology of meniscus pathology: Lessons learned from translational studies and mouse models
Long-term Outcome for Large Meniscal Defects Treated with Small Intestinal Submucosa in a Dog Model
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