Accurate Extraction of Noise Source Impedance of an SMPS Under Operating Conditions

An accurate measurement method to extract the common mode (CM) and the differential mode (DM) noise source impedances of a switched mode power supply (SMPS) under its operating condition is developed and validated. With a proper pre-measurement calibration process, the proposed method allows extraction of both the CM and the DM noise source impedances with very good accuracy. These noise source impedances come in handy to design an electromagnetic interference (EMI) filter for a SMPS systematically with minimum hassl

Rolling of asymmetric disks on an inclined plane

In a recent papers, Turner and Turner (2010 {\em Am. J. Phys.} {\bf 78} 905-7) and Jensen (2011 {\em Eur. J. Phys.} {\bf 32} 389-397) analysed the motion of asymmetric rolling rigid bodies on a horizontal plane. These papers addressed the common misconception that the instantaneous point of contact of the rolling body with the plane can be used to evaluate the angular momentum $\mathbf L$ and the torque $\boldsymbol\tau$ in the equation of motion $d\mathbf L/dt = \boldsymbol\tau$. To obtain the correct equation of motion, the "phantom torque" or various rules that depend on the motion of the point about which $\mathbf L$ and $\boldsymbol\tau$ are evaluated were discussed. In this paper, I consider asymmetric disks rolling down an inclined plane and describe the most basic way of obtaining the correct equation of motion; that is, to choose the point about which $\mathbf L$ and $\boldsymbol\tau$ are evaluated that is stationary in an inertial frame

Pharmacological activation of FOXO3 suppresses triple-negative breast cancer in vitro and in vivo

Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer. Lacking effective therapeutic options hinders treatment of TNBC. Here, we show that bepridil (BPD) and trifluoperazine (TFP), which are FDA-approved drugs for treatment of schizophrenia and angina respectively, inhibit Akt-pS473 phosphorylation and promote FOXO3 nuclear localization and activation in TNBC cells. BPD and TFP inhibit survival and proliferation in TNBC cells and suppress the growth of TNBC tumors, whereas silencing FOXO3 reduces the BPD- and TFP-mediated suppression of survival in TNBC cells. While BPD and TFP decrease the expression of oncogenic c-Myc, KLF5, and dopamine receptor DRD2 in TNBC cells, silencing FOXO3 diminishes BPD- and TFP-mediated repression of the expression of these proteins in TNBC cells. Since c-Myc, KLF5, and DRD2 have been suggested to increase cancer stem cell-like populations in various tumors, reducing these proteins in response to BPD and TFP suggests a novel FOXO3-dependent mechanism underlying BPD- and TFP-induced apoptosis in TNBC cells

Instabilities at [110] Surfaces of d_{x^2-y^2} Superconductors

We compare different scenarios for the low temperature splitting of the zero-energy peak in the local density of states at (110) surfaces of d_{x^2-y^2}-wave superconductors, observed by Covington et al. (Phys.Rev.Lett.79 (1997), 277). Using a tight binding model in the Bogolyubov-de Gennes treatment we find a surface phase transition towards a time-reversal symmetry breaking surface state carrying spontaneous currents and an s+id-wave state. Alternatively, we show that electron correlation leads to a surface phase transition towards a magnetic state corresponding to a local spin density wave state.Comment: 4 pages, 5 figure

Do academically selective school systems strengthen the link between students’ family backgrounds and the likelihood of higher education participation?

Proponents of academic selection argue that academic selection helps children from disadvantaged backgrounds have better lifelong outcomes. However, the evidence needs to be clarified since selections by performance could be a proxy for selection by socioeconomic class. Based on the unique situation in England, where both selective and non-selective systems coexist, we evaluate whether students from selective schools are more likely to continue higher education than those in non-selective schools and whether the link between students’ family backgrounds and their likelihood of higher education participation is stronger under a selective system. The results show that attending selective schools is associated with some post-18 advantages for pupils who stayed until the end of Key Stage 5, but brings disadvantages for those who left at earlier stages, even if we look at the upper bound of the selective school effect. Meanwhile, the link between students’ family backgrounds and future opportunities is consistently stronger under the selective system

Sub-100 nm resolution microscopy based on proximity projection grating scheme

Structured illumination microscopy (SIM) has been widely used in life science imaging applications. The maximum resolution improvement of SIM, compared to conventional bright field system is a factor of 2. Here we present an approach to structured illumination microscopy using the proximity projection grating scheme (PPGS), which has the ability to further enhance the SIM resolution without invoking any nonlinearity response from the sample. With the PPGS-based SIM, sub-100 nm resolution has been obtained experimentally, and results corresponding to 2.4 times resolution improvement are presented. Furthermore, it will be shown that an improvement of greater than 3 times can be achieved

Enhancing Large Language Model Induced Task-Oriented Dialogue Systems Through Look-Forward Motivated Goals

Recently, the development of large language models (LLMs) has been significantly enhanced the question answering and dialogue generation, and makes them become increasingly popular in current practical scenarios. While unlike the general dialogue system which emphasizes the semantic performance, the task-oriented dialogue (ToD) systems aim to achieve the dialogue goal efficiently and successfully in multiple turns. Unfortunately, existing LLM-induced ToD systems lack the direct reward toward the final goal and do not take account of the dialogue proactivity that can strengthen the dialogue efficiency. To fill these gaps, we introduce the ProToD (Proactively Goal-Driven LLM-Induced ToD) approach, which anticipates the future dialogue actions and incorporates the goal-oriented reward signal to enhance ToD systems. Additionally, we present a novel evaluation method that assesses ToD systems based on goal-driven dialogue simulations. This method allows us to gauge user satisfaction, system efficiency and successful rate while overcoming the limitations of current Information and Success metrics. Empirical experiments conducted on the MultiWoZ 2.1 dataset demonstrate that our model can achieve superior performance using only 10% of the data compared to previous end-to-end fully supervised models. This improvement is accompanied by enhanced user satisfaction and efficiency.Comment: 7 Page