A model for A=3 antinuclei production in proton-nucleus collisions

A simple coalescence model based on the same diagrammatic approach of antimatter production in hadronic collisions as used previously for antideuterons is used here for the hadroproduction of mass 3 antinuclei. It is shown that the model is able to reproduce the existing experimental data on Tbar and 3hebar production without any additional parameter.Comment: 7 figures. submitted to Eur. Phys. J.

Nonsingular and accelerated expanding universe from effective Yang-Mills theory

The energy-momentum tensor coming from one-parameter effective Yang- Mills theory is here used to describe the matter-energy content of the homogeneous and isotropic Friedmann cosmology in its early stages. The behavior of all solutions is examined. Particularly, it is shown that only solutions corresponding to an open model allow the universe to evolve into an accelerated expansion. This result appears as a possible mechanism for an inflationary phase produced by a vector field. Further, depending on the value of some parameters characterizing the system, the resulting models are classified as singular or nonsingular.Comment: 15 pages, 7 figures, some discussions were simplified and new remarks were introduce

Asymptotic behavior of the order parameter in a stochastic sandpile

We derive the first four terms in a series for the order paramater (the stationary activity density rho) in the supercritical regime of a one-dimensional stochastic sandpile; in the two-dimensional case the first three terms are reported. We reorganize the pertubation theory for the model, recently derived using a path-integral formalism [R. Dickman e R. Vidigal, J. Phys. A 35, 7269 (2002)], to obtain an expansion for stationary properties. Since the process has a strictly conserved particle density p, the Fourier mode N^{-1} psi_{k=0} -> p, when the number of sites N -> infinity, and so is not a random variable. Isolating this mode, we obtain a new effective action leading to an expansion for rho in the parameter kappa = 1/(1+4p). This requires enumeration and numerical evaluation of more than 200 000 diagrams, for which task we develop a computational algorithm. Predictions derived from this series are in good accord with simulation results. We also discuss the nature of correlation functions and one-site reduced densities in the small-kappa (large-p) limit.Comment: 18 pages, 5 figure

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress

In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking. Here, we first discuss the generality of stress-induced reinstatement to different drugs of abuse, different stressors, and different behavioral procedures. We also discuss neuropharmacological mechanisms, and brain areas and circuits controlling stress-induced reinstatement of drug seeking. We conclude by discussing results from translational human laboratory studies and clinical trials that were inspired by results from rat studies on stress-induced reinstatement. Our main conclusions are (1) The phenomenon of stress-induced reinstatement, first shown with an intermittent footshock stressor in rats trained to self-administer heroin, generalizes to other abused drugs, including cocaine, methamphetamine, nicotine, and alcohol, and is also observed in the conditioned place preference model in rats and mice. This phenomenon, however, is stressor specific and not all stressors induce reinstatement of drug seeking. (2) Neuropharmacological studies indicate the involvement of corticotropin-releasing factor (CRF), noradrenaline, dopamine, glutamate, kappa/dynorphin, and several other peptide and neurotransmitter systems in stress-induced reinstatement. Neuropharmacology and circuitry studies indicate the involvement of CRF and noradrenaline transmission in bed nucleus of stria terminalis and central amygdala, and dopamine, CRF, kappa/dynorphin, and glutamate transmission in other components of the mesocorticolimbic dopamine system (ventral tegmental area, medial prefrontal cortex, orbitofrontal cortex, and nucleus accumbens). (3) Translational human laboratory studies and a recent clinical trial study show the efficacy of alpha-2 adrenoceptor agonists in decreasing stress-induced drug craving and stress-induced initial heroin lapse