Role of Wormwood (Artemisia Absinthium) Extract on Oxidative Stress in Ameliorating Lead Induced Haematotoxicity

Effects of ROS generation have been postulated to be major contributors to lead-exposure related disease. The aim of the study was to investigate the effect of aqueous extract of wormwood (Artemisia absinthium) on oxidative stress in rats protractedly exposed to lead. Aqueous extract of wormwood plant was administered orally (200 mg.kg−1 body weight). Plasma vitamin C, E and non-protein thiol concentrations, red blood cells (RBC) thiobarbituric acid reactive substances, reduced glutathione levels and haemolysis test were evaluated. In addition, RBC antioxidant enzymes activities such as superoxide dismutases, catalase, glutathione peroxidase, glutathione reductase were also estimated. After 11-weeks, significant decreases of plasma vitamin C, E, non protein-thiol (NP-SH) and RBC-reduced glutathione levels were observed in Pb compared to control group (−32.9%, −57.1%, −53.1%, −33.9%, respectively); superoxide dismutase, glutathione peroxidase, uric aminolevulinic acid and haemolysis test significantly increased in Pb compared to control group (+64.3%, +40.3%, +145%, +44.3%, respectively). In our investigation, after 4-weeks of treatment all treated groups did not show any difference compared to the control group, except for glutathione peroxidase and RBC-superoxide dismutase activity (−15.7% and +16.4%, respectively). The findings of this study suggest that wormwood (Artemisia absinthium) extract restored the enzymes activities perturbed by exposure to lead, and had a protective role against lipid peroxidatio

Dose-dependent effects of lead and cadmium and the influence of soil properties on their uptake by Helix aspersa:an ecotoxicity test approach

Three soil types with different physicochemical properties were selected to evaluate their effect on lead and cadmium bioavailability and toxicity in the land snail Helix aspersa. In 28-day ecotoxicity tests, H. aspersa juveniles were exposed to increasing concentrations of Pb or Cd. EC50s, concentrations reducing snail growth by 50%, differed between the soils and so did Cd and Pb uptake in the snails. For lead, EC50s were 2397–6357 mg Pb/kg dry soil, while they ranged between 327 and 910 mg Cd/kg dry soil for cadmium. Toxicity and metal uptake were highest on the soil with the lowest pH, organic matter content and Cation Exchange Capacity (CEC). Growth reduction was correlated with metal accumulation levels in the snails’ soft body, and differences in toxicity between the soils decreased when EC50s were expressed on the basis of internal metal concentrations in the snails. These results confirm the effect of soil properties; pH, CEC, OM content, on the uptake and growth effect of Pb and Cd in H. aspersa, indicating the importance of properly characterizing soils when assessing the environmental risk of metal contaminated sites

Abstracts of 1st International Conference on Computational & Applied Physics

This book contains the abstracts of the papers presented at the International Conference on Computational & Applied Physics (ICCAP’2021) Organized by the Surfaces, Interfaces and Thin Films Laboratory (LASICOM), Department of Physics, Faculty of Science, University Saad Dahleb Blida 1, Algeria, held on 26–28 September 2021. The Conference had a variety of Plenary Lectures, Oral sessions, and E-Poster Presentations. Conference Title: 1st International Conference on Computational & Applied PhysicsConference Acronym: ICCAP’2021Conference Date: 26–28 September 2021Conference Location: Online (Virtual Conference)Conference Organizer: Surfaces, Interfaces, and Thin Films Laboratory (LASICOM), Department of Physics, Faculty of Science, University Saad Dahleb Blida 1, Algeria