Geophysical constraint on a relic background of the dilatons

According to a scenario in string cosmology, a relic background of light dilatons can be a significant component of the dark matter in the Universe. A new approach of searching for such a dilatonic background by observing Earth's surface gravity was proposed in my previous work. In this paper, the concept of the geophysical search is briefly reviewed, and the geophysical constraint on the dilaton background is presented as a function of the strength of the dilaton coupling, $q_b^2$. For simplicity, I focus on massless dilatons and assume a simple Earth model. With the current upper limit on $q_b^2$, we obtain the upper limit on the dimensionless energy density of the massless background, $\Omega_{DW}h^2_{100} \leq 6 \times 10^{-7}$, which is about one-order of magnitude more stringent than the one from astrophysical observations, at the frequency of $\sim$ 7 $\times$ 10$^{-5}$ Hz. If the magnitude of $q_b^2$ is experimentally found to be smaller than the current upper limit by one order of magnitude, the geophysical upper limit on $\Omega_{DW}h^2_{100}$ becomes less stringent and comparable to the one obtained from the astrophysical observations.Comment: 6 pages, Proceedings for the 8th Edoardo Amaldi Conference on Gravitational Waves, 21-26 June, 2009, Columbia University, New York, US

Orchestrating Forest Policy in Italy: Mission Impossible?

In the Italian political and economic agenda the forest sector occupies a marginal role. The forest sector in Italy is characterized by a high institutional fragmentation and centralized decision-making processes dominated by Public Forest Administrations. Public participation in forest policy processes has been implemented since the 1990s at national, regional and local levels in several cases. However, today no significant changes have been observed in the overall governance of the forest sector and stakeholders' involvement in Italian forest policy decision-making is still rather limited. The aims of this paper are to describe the state of forest-related participatory processes in Italy at various levels (national, regional and local) and identify which factors and actors hinder or support the establishment and implementation of participatory forest-related processes in the country. The forest-related participatory processes are analyzed adopting a qualitative-based approach and interpreting interactive, complex and non-linear participatory processes through the lens of panarchy theory

Living myocardial slices for the study of nucleic acid-based therapies

Gene therapy based on viral vectors offers great potential for the study and the treatment of cardiac diseases. Here we explore the use of Living Myocardial Slices (LMS) as a platform for nucleic acid-based therapies. Rat LMS and Adeno-Associated viruses (AAV) were used to optimise and analyse gene transfer efficiency, viability, tissue functionality, and cell tropism in cardiac tissue. Human cardiac tissue from failing (dilated cardiomyopathy) hearts was also used to validate the model in a more translational setting. LMS were cultured at physiological sarcomere length for 72-h under electrical stimulation. Two recombinant AAV serotypes (AAV6 and AAV9) at different multiplicity of infection (MOI) expressing enhanced green fluorescent protein (eGFP) were added to the surface of rat LMS. AAV6 at 20,000 MOI proved to be the most suitable serotype without affecting LMS contractility or kinetics and showing high transduction and penetrability efficiency in rat LMS. This serotype exhibited 40% of transduction efficiency in cardiomyocytes and stromal cells while 20% of the endothelial cells were transduced. With great translational relevance, this protocol introduces the use of LMS as a model for nucleic acid-based therapies, allowing the acceleration of preclinical studies for cardiac diseases

A three-day forest-bathing retreat enhances positive affect, vitality, optimism, and gratitude: An option for green-care tourism in Italy?

Forest-bathing experiences can be seen as guided recreational activities led by non-clinical trained practitioners in the context of green, slow, and mindful tourism. Notwithstanding its growing practice, there is a lack of research on the psychological benefits which can help support nature-based tourism destination managers in unlocking the potential of this emerging tourism demand. This study will fill in this gap by testing the hypothesis that a three-day forest-bathing retreat, which fits with the most common type of holidays in Europe, will enhance positive affect, vitality, optimism, and gratitude as indicators of hedonic and eudaimonic well-being. Forty-four adults were involved in the residential program and filled-in self-report questionnaires before and after the experience to assess the well-being dimensions considered. Results showed a significant increase for all the assessed variables. We conclude that forest bathing as a mindful tourism practice carried out in natural settings dominated by forests can favor hedonic and eudaimonic well-being, thus becoming a potential source of attractiveness for nature-based touristic destinations, but more transdisciplinary efforts are needed to exploit this potential. In particular, research gaps still exist in Europe on cause-effect relations between forest features and psychological benefits, how forests could be managed to guarantee these benefits to the advantage of a tourism destination, and how tourism and forest management sectors could collaborate in this direction

Importancia del tamaño de partícula y el uso de inoculante en ensilajes

Objective with this review discuss the importance of proper adjustment of the particle size at harvest of corn silage and the use or non use of inoculants. Silages have received greater emphasis by the ranchers, by requiring simple technology and provide excellent results, with the confection less limited by climatic factors compared with haying. The particle sizes can contribute to changes in the fermentation of silage by means of different densities in the silo, this may also cause changes in chewing activities and performance of ruminant animals. The fermentation in the silo is a complex and dynamic process that is affected by variety of factors inherent to the management therefore has intensified the use of bacterial inoculants to accelerate the fermentation of forage ensure low losses during the unloading process. There is still a large space for research to elucidate the effect of setting the true effects in particle size associated with the use of bacterial inoculants in relation to the silo environment and mainly as animal performance.El objetivo de la presente revisión es discutir sobre la importancia del ajuste adecuado del tamaño de partícula en el momento de la colecta de la planta de maíz al ser ensilada y del uso o no de inoculante bacteriano. Los ensilajes han sido ampliamente utilizados por los ganaderos por exigir tecnologías simples y presentar resultados satisfactorios, ya que esta tecnología de conservación es menos dependiente de factores climáticos, en comparación al heno. El tamaño de corte de las partículas puede causar modificaciones en la fermentación de la masa ensilada, a través de diferentes densidades obtenidas en el silo, lo que a su vez puede provocar modificaciones en la actividad masticatoria e en el desempeño de los rumiantes. La fermentación en el silo es un proceso complejo y dinámico que es afectado por una gran variedad de factores inherentes al manejo, por eso, se ha intensificado el uso de inoculantes bacterianos para acelerar la fermentación del forraje y disminuir las pérdidas durante el proceso de descargue. Todavía existe un gran espacio para investigar sobre los verdaderos efectos del ajuste en el tamaño de partícula asociada al uso de inoculantes bacterianos, tanto en lo que se refiere al ambiente del silo como al desempeño animal

Optical coherence tomography guidance for percutaneous coronary intervention with bioresorbable scaffolds

Background The effect of optical coherence tomography (OCT) guidance on the implantation strategy during all phases of percutaneous coronary intervention (PCI) with bioresorbable vascular scaffolds (BVSs) in a real-world scenario has been poorly investigated. Methods Consecutive patients undergoing BVS implantation at our institution were included in this registry. Frequency-domain OCT pullbacks were performed at the operator's discretion during all phases of BVS implantation procedures to optimize preparation of lesions, confirm BVS size, and optimize expansion and apposition of scaffolds. Results Between September 2012 and July 2015, 203 BVSs were implanted in 101 consecutive patients at our institution (2.01 BVSs/patient). In 66 patients, the procedure was performed under OCT guidance. In the OCT subgroup, 66 (77.6%) of the 85 treated lesions were complex (B2/C AHA/ACC type). Overall, 147 OCT pullbacks were performed and 72/147 (49.0%) pullbacks indicated the need for changing strategy. After angiography-only-guided optimisation of BVS in 27 (31.8%) lesions, an OCT examination prompted performance of a second post-expansion. This resulted in an increase in the minimal scaffold area (5.5 to 6.3\ua0mm2, p\ua0=\ua00.004) and a decrease in the incomplete scaffold apposition area (1.1 to 0.6\ua0mm2, p\ua0=\ua00.082), with no new stent fractures. When the population was divided according to the time of BVS implantation, an initial learning adaptation became evident, with the number of OCT-guided changes in strategy significantly decreasing between the initial and final time periods (p\ua0=\ua00.017). Conclusions OCT guidance for BVS implantation significantly affects the procedural strategy, with favourable effects on acute results and the learning curve