Разработка технологии утилизации отходов птицеводства в кормовую добавку

В статье рассматриваются проблемы утилизации перо-пухового сырья птицефабрик в высокобелковые корма и кормовые продукты для сельскохозяйственных животных и птиц. Представлена актуальность и приоритет разработки данного направления в развития нашей страны. Показана рациональность применения перо-пуховых отходов в качестве источника белковых веществ в рационах сельскохозяйственных животных и птиц. Рассмотрена модель структуры главного белка пера - кератина. Предложена технологическая схема производства биопрепарата на основе культур промышленных непатогенных микроорганизмов: Bacillus pumilus SAFR-032, Microbacterium terregens AC1180, Bacillus fastidiosus B11090, Arthrobacter globiformis AC1529, Streptomyces olivocinereus AC1169, Acinetobacter sp. B3905 для утилизации кератинсодержащих отходов, а также технологические этапы производства кормовой добавки из перо-пуховых отходов с применением разработанного биопрепарата.In the annotation the problems of perception of disposing feather-down raw poultry farms in high-protein forage and fodder products for agricultural animals and birds are considered in the article. The urgency and priority of developing this direction in the development of our country is presented. It shows a rational application of down-feather waste as a source of proteins in the diet of farm animals and birds. A model of the structure of the main protein of the pen - keratin is considered. Bioproduct proposed technological production scheme based on industrial crops nonpathogenic microorganisms: Bacillus pumilus SAFR-032, Microbacterium terregens AC1180, Bacillus fastidiosus B11090, Arthrobacter globiformis AC1529, Streptomyces olivocinereus AC1169, Acinetobacter sp. B3905 keratin-waste for recycling, as well as the technological stages of production of the feed additive of the pen-feather waste developed using a biological product

Paradox of circulating advanced glycation end product concentrations in patients with congestive heart failure and after heart transplantation

Objectives: To analyse circulating concentrations of advanced glycation end products (AGEs) in patients with severe congestive heart failure (CHF) and after heart transplantation; to identify the potential contribution of kidney function to plasma AGE concentrations; and to determine whether AGE concentrations and parameters of oxidative stress are interrelated.Methods and results: Circulating N-epsilon-(carboxymethyl) lysine (CML) and AGE associated fluorescence (AGE-Fl), lipid peroxidation, and glomerular filtration rate (GFR) were measured in a cross sectional study of 22 patients with advanced CHF, 30 heart transplant recipients, and 20 healthy controls. Compared with the controls, the CHF patients had decreased CML (mean(SEM) 467.8 (20.0) ng/ml v 369.3 (22.3) ng/ml, p<0.01), AGE- Fl (mean (SEM) 302.2 (13.3) arbitrary units v 204.9 (15.7) arbitrary units, p<0.01), and GFR (p<0.01). CML was positively related to decreased total protein and serum albumin and negatively to body mass index (p<0.01). In contrast, in the heart transplant group, impaired GFR was associated with a notable rise of both CML (mean (SEM) 876.1 (53.1) ng/ml, p<0.01) and AGE- Fl (mean (SEM) 385.6 (26.1) arbitrary units, p<0.01). A positive relation between CML and serum albumin (r=0.394, p<0.05) and lipofuscin (r=0.651, p<0.01) was found.Conclusions: The contrasting concentration of CML and AGE- Fl between patients with CHF and after heart transplantation in the presence of decreased GFR and oxidative stress are explained by lowered plasma proteins in CHF and higher concentrations in heart transplant recipients. In heart transplant recipients, in addition to myocardial inflammatory processes, immunosuppression may be important for enhanced formation of AGEs