Efectividad del marketing de proximidad mediante tecnología bluetooth

Tesis (Ingeniería Comercial)La presente investigación consiste en analizar el comportamitento de los consumidores frente a una nueva herramienta publicitaria, información comercial y promociones vía Bluetooth a través de paletas publicitarias directamente al celular, la cual analizaremos en dos partes, primero en un Focus Group realizado al curso de "Investigación de mercados" y luego en el Mali Marina Arauco. Para ambos casos utilizaremos como herramienta una encuesta pero de diferentes tipos, en la primera etapa usaremos una encuesta abierta para realizar un "brainstorming" y en la segunda etapa usaremos una encuesta concluyente, estructurada y dicotómica. Para el caso del Focus Group se trabajó en base a los datos proporcionados por los mismos alumnos de la clase ya que esa es la idea de este método, poder captar la mayor cantidad de información posible acerca de los conceptos que estamos analizando. Por parte de la encuesta al Mall, se trabajó con los flujos de entrada de los 14 accesos pero tomando en consideración los más representativos que fueron el acceso por la pasarela de 15 norte y la entrada de 14 norte con libertad. Una vez realizado nuestras dos metodologías de investigación podemos definir que los consumidores por ahora no aceptan esta nueva herramienta publicitaria ya que consideran poco seguro tener el Bluetooth activo debido a los constantes Hackeos a diferentes aparatos tecnológicos, la falta a la privacidad y consideran que podría llegar a ser invasivo

Definición de procesos de administración de documentos

Tesis (Ingeniero en Computación e Informática)El proyecto fue realizado para la empresa Tecnolex S.A., y se extendió a las distintas áreas de la empresa. La firma se encarga de ofrecer servicios tecnológicos a distintos estudios de abogados en Chile, y en estos momentos se encuentra en expansión hacia Latinoamérica. La administración de documentos aún no ha sido normada en la empresa, donde el manejo de documentos sólo es llevado por el orden de los usuarios. Además, tampoco existen procesos definidos para la aceptación de Proyectos. La solución consiste en la implantación del Software Administrador de documentos Worksite, que a su vez se integrará a un módulo web que concatenará los datos del sistema de cobranza de la empresa

Convective drying of osmo-treated abalone (haliotis rufescens) slices: diffusion, modeling, and quality features

The focus of this research was based on the application of an osmotic pretreatment (15% NaCl) for drying abalone slices, and it evaluates the influence of hot-air drying temperature (40-80 degrees C) on the product quality. In addition, the mass transfer kinetics of salt and water was also studied. The optimal time of the osmotic treatment was established until reaching a pseudo equilibrium state of the water and salt content (290 min). The water effective diffusivity values during drying ranged from 3.76 to 4.75 x 10(-9) m(2)/s for three selected temperatures (40, 60, and 80 degrees C). In addition, experimental data were fitted by Weibull distribution model. The modified Weibull model provided good fitting of experimental data according to applied statistical tests. Regarding the evaluated quality parameters, the color of the surface showed a change more significant at high temperature (80 degrees C), whereas the nonenzymatic browning and texture showed a decrease during drying process mainly due to changes in protein matrix and rehydration rates, respectively. In particular, working at 60 degrees C resulted in dried samples with the highest quality parameters.Concurso DIULS Apoyo Tesis de Postgrado Project PT14332 FONDECYT Regular Project 114006

Biochemical, Catabolic, and PGP Activity of Microbial Communities and Bacterial Strains from the Root Zone of <i>Baccharis linearis</i> in a Mediterranean Mine Tailing

The management of mine tailings (MT) is commonly workload heavy, intrusive, and expensive. Phytostabilization offers a promising approach for MT management; however, it poses challenges due to the unfavorable physicochemical properties of these wastes. Nevertheless, native microorganisms capable of supporting plant growth and development could enhance the efficacy of phytostabilization. This study assesses the biological activity of microbial communities from the root zone of Baccharis linearis, which is naturally present in MT, in order to evaluate their biotechnological potential for phytostabilization. The root zone and bulk samples were collected from B. linearis plants located within a MT in the Mediterranean zone of Chile. Enzyme activities related to the cycling of C, N, and P were assessed. The community-level physiological profile was evaluated using the MicroRespTM system. Bacterial plant growth-promoting (PGP) traits and colony forming units (CFU) were evaluated through qualitative and microbiological methods, respectively. CFU, enzyme activities, and CLPP were higher in the root zone compared with the bulk samples. Five bacterial strains from the root zone exhibited PGP traits such as P solubilization and N acquisition, among others. The presence of microbial communities in the root zone of B. linearis with PGP traits suggests their potential to enhance the ecological management of MT through phytostabilization programs

A molecular stratification of chilean gastric cancer patients with potential clinical applicability

Gastric cancer (GC) is a complex and heterogeneous disease. In recent decades, The Cancer Genome Atlas (TCGA) and the Asian Cancer Research Group (ACRG) defined GC molecular subtypes. Unfortunately, these systems require high-cost and complex techniques and consequently their impact in the clinic has remained limited. Additionally, most of these studies are based on European, Asian, or North American GC cohorts. Herein, we report a molecular classification of Chilean GC patients into five subtypes, based on immunohistochemical (IHC) and in situ hybridization (ISH) methods. These were Epstein–Barr virus positive (EBV+), mismatch repair-deficient (MMR-D), epithelial to mesenchymal transition (EMT)-like, and accumulated (p53+) or undetected p53 (p53−). Given its lower costs this system has the potential for clinical applicability. Our results confirm relevant molecular alterations previously reported by TCGA and ACRG. We confirm EBV+ and MMR-D patients had the best prognosis and could be candidates for immunotherapy. Conversely, EMT-like displayed the poorest prognosis; our data suggest FGFR2 or KRAS could serve as potential actionable targets for these patients. Finally, we propose a low-cost step-by-step stratification system for GC patients. To the best of our knowledge, this is the first Latin American report on a molecular classification for GC. Pending further validation, this stratification system could be implemented into the routine clinic

Chilean registry for neuroendocrine tumors: a Latin American perspective

Neuroendocrine tumors (NETs) are relatively rare and highly heterogeneous neoplasms. Despite this, recent studies from North America and Central Europe have suggested an increase in incidence. In Latin America, NET data are scarce and scattered with only a few studies reporting registries. Our goal was to establish a NET registry in Chile. Here, we report the establishment and our first 166 NET patients. We observed a slight preponderance of males, a median age at diagnosis of 53\ua0years and a median overall survival of 110\ua0months. As anticipated, most tumors were gastroenteropancreatic (GEP). Survival analyses demonstrated that non-GEP or stage IV tumors presented significantly lower overall survival (OS). Similarly, patients with surgery classified as R0 had better OS compared to R1, R2, or no surgery. Furthermore, patients with elevated chromogranin A (CgA) or high Ki67 showed a trend to poorer OS; however, these differences did not reach statistical significance (log-rank test p = 0.07). To the best of our knowledge, this is the first report of a NET registry in Chile. Median OS in our registry (110\ua0months) is in line with other registries from Argentina and Spain. Other variables including age at diagnosis and gender were similar to previous studies; however, our data indicate a high proportion of small-bowel NETs compared to other cohorts, reflecting the need for NET regional registries. Indeed, these registries may explain regional discrepancies in incidence and distribution, adding to our knowledge on this seemingly rare, highly heterogeneous disease