Effect of total intravenous versus inhalation anesthesia on long-term oncological outcomes in patients undergoing curative resection for early-stage non-small cell lung cancer: a retrospective cohort study

Background Propofol-based total intravenous anesthesia (TIVA) improves long-term outcomes after cancer surgery compared with inhalation anesthesia. However, its effect on patients undergoing non-small cell lung cancer (NSCLC) surgery remains unclear. We aimed to compare the oncological outcomes of TIVA and inhalation anesthesia after curative resection of early-stage NSCLC. Methods We analyzed the medical records of patients diagnosed with stage I or II NSCLC who underwent curative resection at a tertiary university hospital between January 2010 and December 2017. The primary outcomes were recurrence-free survival (RFS) and overall survival (OS) according to anesthesia type. Results We included 1,508 patients with stage I/II NSCLC. The patients were divided into the TIVA (n = 980) and Inhalation (n = 528) groups. The two groups were well-balanced in terms of baseline clinical characteristics. The TIVA group demonstrated significantly improved RFS (7.7 years, 95% CI [7.37, 8.02]) compared with the Inhalation group (6.8 years, 95% CI [6.30, 7.22], P = 0.003). Similarly, TIVA was superior to inhalation agents with respect to OS (median OS; 8.4 years, 95% CI [8.08, 8.69] vs. 7.3 years, 95% CI [6.81, 7.71]; P < 0.001). Multivariable Cox regression analysis revealed that TIVA was an independent prognostic factor related to recurrence (hazard ratio [HR]: 1.24, 95% CI [1.04, 1.47], P = 0.014) and OS (HR: 1.39, 95% CI [1.12, 1.72], P = 0.002). Conclusions Propofol-based TIVA was associated with better RFS and OS than inhalation anesthesia in patients with stage I/II NSCLC who underwent curative resection

Creating smarter and more sustainable cities in Southeast Asia : a roadmap for United States-South Korea cooperation

Click HERE to view the recording of the companion webinar. This APB and its companion webinar were produced as a part of the United States-Republic of Korea (ROK) Cooperation in Southeast Asia: Trade, Investment, and Multilateralism webinar series and online, collaborative policy research program, a joint effort between the East-West Center in Washington and the Korea Foundation, which generously sponsors the program.For more about the East-West Center, see https://www.eastwestcenter.org/Ms. Sea Young "Sarah" Kim, Visiting Scholar at the East-West Center in Washington and PhD student at Yonsei University, explains that "Washington's and Seoul's mutual interest in smart cities presents a valuable opportunity for the two nations to engage in tactical cooperation... under the broader framework of addressing non-traditional regional threats.

Internal Market for Executives: Inter-divisional Resource Sharing and Executive Transfer

The problem of resource allocation is a particularly pressing issue in large and highly diversified companies, where business divisions of different industry dynamics compete for limited resources. However, prior work has focused primarily on impersonal, often structural, mechanisms for resource coordination and control, paying scant attention to the actual process involving human agents such as executives who perform the role of coordination and control in strategic resource allocation decisions. To address this situation, we explore how the inter-divisional mobility of executives serves as a key mechanism to manage the corporate-wide sharing of both tangible and intangible resources. Using business groups in Korea from 1989 to 2006 as an empirical setting, we demonstrate that patterns of executive transfer among divisions clearly coincide with group-level resources and intra-group dependence relationship. Our results also show that such patterns are reshaped by the influence of external environments, i.e., product market competition and capital market control. This study highlights the unique importance of executives who carry the role of coordination and control in sharing resources within a firm, and thereby provides new insight for extant research that has viewed internal labor markets as sources of individual or firm-specific skills

Interunit Executive Redeployment in Multiunit Firms: Evidence from Korean Business Groups

Building on the literature on resource reconfiguration theory, we formulate a new theoretical framework that explains how executive redeployment within a diversified firm transfers different types of human capital embodied in executives to different units facing specific business challenges. In the empirical context of Korean business groups, we find that executives with unit-specific human capital, like turnaround experience, competitive experience, and international expansion experience, are redeployed to units with corresponding business challenges like financial difficulties, intensifying competition, and early-stage international expansion, respectively. We also show that executives with unit generic human capital, like corporate management practices and interunit coordination experiences, are redeployed to younger units seeking to establish corporate-level policies and practices. Additional analyses also show that the value of firm-specific human capital in driving the redeployment of executives is contingent on their functional orientation and seniority

The bounds of boundaryless careers : the contigent value of human capital in job mobility

NUS Business School Research Paper Series; 2012-0021-4

Favorite sons or hired guns : the shifting balance in the face of environmental changes

NUS Business School Research Paper Series; 2012-0031-4