773 research outputs found

    A 3-D Track-Finding Processor for the CMS Level-1 Muon Trigger

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    We report on the design and test results of a prototype processor for the CMS Level-1 trigger that performs 3-D track reconstruction and measurement from data recorded by the cathode strip chambers of the endcap muon system. The tracking algorithms are written in C++ using a class library we developed that facilitates automatic conversion to Verilog. The code is synthesized into firmware for field-programmable gate-arrays from the Xilinx Virtex-II series. A second-generation prototype has been developed and is currently under test. It performs regional track-finding in a 60 degree azimuthal sector and accepts 3 GB/s of input data synchronously with the 40 MHz beam crossing frequency. The latency of the track-finding algorithms is expected to be 250 ns, including geometrical alignment correction of incoming track segments and a final momentum assignment based on the muon trajectory in the non-uniform magnetic field in the CMS endcaps.Comment: 7 pages, 5 figures, proceedings for the conference on Computing in High Energy and Nuclear Physics, March 24-28 2003, La Jolla, Californi

    Mapping Brucellosis Increases Relative to Elk Density using Hierarchical Bayesian Models

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    The relationship between host density and parasite transmission is central to the effectiveness of many management strategies. We applied hierarchical Bayesian methods to an 18-yr dataset on elk (Cervus elaphus) brucellosis in the Greater Yellowstone Ecosystem (GYE) and found that increases in brucellosis seroprevalence were strongly correlated with elk densities. Elk that were densely aggregated on supplemental feeding grounds had higher seroprevalence in 1991, but by 2008 many areas distant from the feeding grounds were of comparable seroprevalence. Thus, brucellosis appears to be expanding its range into areas of higher elk density, which is likely to further complicate the United States brucellosis eradication program. The data could not differentiate among linear and non-linear effects of host density, which is a critical area where research can inform management actions. This study is an example of how the dynamics of host populations can affect their ability to serve as disease reservoirs

    Parsing the Effects of Demography, Climate and Management on Recurrent Brucellosis Outbreaks in Elk

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    Zoonotic pathogens can harm human health and well‐being directly or by impacting livestock. Pathogens that spillover from wildlife can also impair conservation efforts if humans perceive wildlife as pests. Brucellosis, caused by the bacterium Brucella abortus, circulates in elk and bison herds of the Greater Yellowstone Ecosystem and poses a risk to cattle and humans. Our goal was to understand the relative effects of climatic drivers, host demography and management control programmes on disease dynamics. Using \u3e20 years of serologic, demographic and environmental data on brucellosis in elk, we built stochastic compartmental models to assess the influences of climate forcing, herd immunity, population turnover and management interventions on pathogen transmission. Data were collected at feedgrounds visited in winter by free‐ranging elk in Wyoming, USA. Snowpack, hypothesized as a driver of elk aggregation and thus brucellosis transmission, was strongly correlated across feedgrounds. We expected this variable to drive synchronized disease dynamics across herds. Instead, we demonstrate asynchronous epizootics driven by variation in demographic rates. We evaluated the effectiveness of test‐and‐slaughter of seropositive female elk at two feedgrounds. Test‐and‐slaughter temporarily reduced herd‐level seroprevalence but likely reduced herd immunity while removing few infectious individuals, resulting in subsequent outbreaks once the intervention ceased. We simulated an alternative strategy of removing seronegative female elk and found it would increase herd immunity, yielding fewer infections. We evaluated a second experimental treatment wherein feeding density was reduced at one feedground, but we found no evidence for an effect despite a decade of implementation. Synthesis and applications. Positive serostatus is often weakly correlated with infectiousness but is nevertheless used to make management decisions including lethal removal in wildlife disease systems. We show how this can have adverse consequences whereas efforts that maintain herd immunity can have longer‐term protective effects. Climatic drivers may not result in synchronous disease dynamics across populations unless vital rates are also similar because demographic factors have a large influence on disease patterns

    SUSY Survey with Inclusive Muon and Same-Sign Dimuon Accompanied by Jets and MET with CMS

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    Generic signatures of supersymmetry with R-parity conservation include those of single isolated muons or like-sign isolated dimuon pairs, accompanied with energetic jets and missing transverse energy. The ability of CMS to discover supersymmetry with these signals is estimated for 10 fb^{-1} of data collected with the inclusive single-muon and dimuon High-Level-Trigger paths. The selection criteria are optimized and the systematic effects are studied for a single low-mass benchmark point of the constrained MSSM with m_0 = 60,GeV/c^2, m_{1/2} = 250,GeVc^2, tan beta=10, A_0=0 and mu> 0. Discovery contours in the m_0, m_{1/2}) plane are presented for integrated luminosities ranging from 1 to 100, fb^{-1}

    The CMS Modular Track Finder boards, MTF6 and MTF7

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    To accommodate the increase in energy and luminosity of the upgraded LHC, the CMS Endcap Muon Level 1 Trigger system has to be significantly modified. To provide the best track reconstruction, the Trigger system must now import all available trigger primitives generated by Cathode Strip Chambers and by other regional subsystems, such as Resistive Plate Chambers. In addition to massive input bandwidth, this also requires a significant increase in logic and memory resources. To satisfy these requirements, a new Sector Processor unit for muon track finding is being designed. This unit follows the micro-TCA standard recently adopted by CMS. It consists of three modules. The Core Logic module houses the large FPGA that contains the processing logic and multi-gigabit serial links for data exchange. The Optical module contains optical receivers and transmitters; it communicates with the Core Logic module via a custom backplane section. The Look-Up Table module contains a large amount of low-latency memory that is used to assign the final transverse momentum of the muon candidate tracks. The name of the unit — Modular Track Finder — reflects the modular approach used in the design. Presented here are the details of the hardware design of the prototype unit based on Xilinx's Virtex-6 FPGA family, MTF6, as well as results of the conducted tests. Also presented are plans for the pre-production prototype based on the Virtex-7 FPGA family, MTF7

    Reversible and Irreversible Interactions of Poly(3-hexylthiophene) with Oxygen Studied by Spin-Sensitive Methods

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    Understanding of degradation mechanisms in polymer:fullerene bulk-heterojunctions on the microscopic level aimed at improving their intrinsic stability is crucial for the breakthrough of organic photovoltaics. These materials are vulnerable to exposure to light and/or oxygen, hence they involve electronic excitations. To unambiguously probe the excited states of various multiplicities and their reactions with oxygen, we applied combined magneto-optical methods based on multifrequency (9 and 275 GHz) electron paramagnetic resonance (EPR), photoluminescence (PL), and PL-detected magnetic resonance (PLDMR) to the conjugated polymer poly(3-hexylthiophene) (P3HT) and polymer:fullerene bulk heterojunctions (P3HT:PCBM; PCBM = [6,6]-phenyl-C61-butyric acid methyl ester). We identified two distinct photochemical reaction routes, one being fully reversible and related to the formation of polymer:oxygen charge transfer complexes, the other one, irreversible, being related to the formation of singlet oxygen under participation of bound triplet excitons on the polymer chain. With respect to the blends, we discuss the protective effect of the methanofullerenes on the conjugated polymer bypassing the triplet exciton generation

    Probable causes of increasing brucellosis in free-ranging elk of the Greater Yellowstone Ecosystem

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    While many wildlife species are threatened, some populations have recovered from previous Overexploitation, and data linking these population increases with disease dynamics are limited. We present data suggesting that free-ranging elk (Cervus elaphus) are a maintenance host for Brucella abortus in new areas of the Greater Yellowstone Ecosystem (GYE). Brucellosis seroprevalence in free-ranging elk increased from 0-7% in 1991-1992 to 8 20% in 2006-2007 in four of six herd units around the GYE. These levels of brucellosis are comparable to some herd units where elk are artificially aggregated on supplemental feeding grounds. There are several possible mechanisms for this increase that we evaluated using statistical and population modeling approaches. Simulations of an age-structured population model suggest that the observed levels of seroprevalence are unlikely to be sustained by dispersal from supplemental feeding areas with relatively high seroprevalence or an older age structure. Increases in brucellosis seroprevalence and the total elk population size in areas with feeding grounds have not been statistically detectable. Meanwhile, the rate of seroprevalence increase outside the feeding grounds was related to the population size and density of each herd unit. Therefore, the data suggest that enhanced elk-to-elk transmission in free-ranging populations may be occurring due to larger winter elk aggregations. Elk populations inside and outside of the GYE that traditionally did not maintain brucellosis may now be at risk due to recent population increases. In particular, some neighboring populations of Montana elk were 5-9 times larger in 2007 than in the 1970s, with some aggregations comparable to the Wyoming feeding-ground populations. Addressing the unintended consequences of these increasing populations is complicated by limited hunter access to private lands, which places many ungulate populations out of administrative control. Agency-landowner hunting access partnerships and the protection of large predators are two management strategies that may be used to target high ungulate densities in private refuges and reduce the current and future burden of disease
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