The \u27new\u27 middle class in India: a re-assessment

[extract] This paper seeks to go some way towards unravelling the impact of neo-liberal policies on classbased cultures in India. Specifically, it focuses on the experiences and worldviews of the middle classes, the class group or fraction said to have expanded greatly in recent times and to have been the main beneficiaries of the neo-liberal reforms of the Indian economy instigated in the early 1990s. In this paper, we explore two dimensions of these changes: work and discourses of efficiency; and the impact of these reforms on gender and class relations

Designing for the Infrastructure of the Supply Chain of Malay Handwoven Songket in Terengganu

The growing HCI interest in developing contexts and cultural craft practices is ripe to focus on their under-explored homegrown sociotechnical infrastructures. This paper explores the creative infrastructural actions embedded within the practices of songket's supply chain in Terengganu, Malaysia. We report on contextual interviews with 92 participants including preparation workers, weavers, designers, merchants, and customers. Findings indicate that increased creative infrastructural actions are reflected in these actors' resourcefulness for mobilizing information, materials, and equipment, and for making creative artifacts through new technologies weaved within traditional practices. We propose two novel approaches to design in this craft-based infrastructure. First, we explore designing for the social layer of infrastructure and its mutually advantageous exploitative relationships rooted in culture and traditions. Second, we suggest designing for roaming value-creation artifacts, which blend physical and digital materializations of songket textile design. Developed through a collaborative and asynchronous process, we argue that these artifacts represent less-explored vehicles for value co-creation, and that sociotechnical infrastructures as emerging sites of innovation could benefit from HCI research

Mortality Among Adults With Cancer Undergoing Chemotherapy or Immunotherapy and Infected With COVID-19

Importance: Large cohorts of patients with active cancers and COVID-19 infection are needed to provide evidence of the association of recent cancer treatment and cancer type with COVID-19 mortality. // Objective: To evaluate whether systemic anticancer treatments (SACTs), tumor subtypes, patient demographic characteristics (age and sex), and comorbidities are associated with COVID-19 mortality. // Design, Setting, and Participants: The UK Coronavirus Cancer Monitoring Project (UKCCMP) is a prospective cohort study conducted at 69 UK cancer hospitals among adult patients (≥18 years) with an active cancer and a clinical diagnosis of COVID-19. Patients registered from March 18 to August 1, 2020, were included in this analysis. // Exposures: SACT, tumor subtype, patient demographic characteristics (eg, age, sex, body mass index, race and ethnicity, smoking history), and comorbidities were investigated. // Main Outcomes and Measures: The primary end point was all-cause mortality within the primary hospitalization. // Results: Overall, 2515 of 2786 patients registered during the study period were included; 1464 (58%) were men; and the median (IQR) age was 72 (62-80) years. The mortality rate was 38% (966 patients). The data suggest an association between higher mortality in patients with hematological malignant neoplasms irrespective of recent SACT, particularly in those with acute leukemias or myelodysplastic syndrome (OR, 2.16; 95% CI, 1.30-3.60) and myeloma or plasmacytoma (OR, 1.53; 95% CI, 1.04-2.26). Lung cancer was also significantly associated with higher COVID-19–related mortality (OR, 1.58; 95% CI, 1.11-2.25). No association between higher mortality and receiving chemotherapy in the 4 weeks before COVID-19 diagnosis was observed after correcting for the crucial confounders of age, sex, and comorbidities. An association between lower mortality and receiving immunotherapy in the 4 weeks before COVID-19 diagnosis was observed (immunotherapy vs no cancer therapy: OR, 0.52; 95% CI, 0.31-0.86). // Conclusions and Relevance: The findings of this study of patients with active cancer suggest that recent SACT is not associated with inferior outcomes from COVID-19 infection. This has relevance for the care of patients with cancer requiring treatment, particularly in countries experiencing an increase in COVID-19 case numbers. Important differences in outcomes among patients with hematological and lung cancers were observed

Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among Europeans

Genome-wide association studies (GWAS) have identified numerous common prostate cancer (PrCa) susceptibility loci. We have fine-mapped 64 GWAS regions known at the conclusion of the iCOGS study using large-scale genotyping and imputation in 25 723 PrCa cases and 26 274 controls of European ancestry. We detected evidence for multiple independent signals at 16 regions, 12 of which contained additional newly identified significant associations. A single signal comprising a spectrum of correlated variation was observed at 39 regions; 35 of which are now described by a novel more significantly associated lead SNP, while the originally reported variant remained as the lead SNP only in 4 regions. We also confirmed two association signals in Europeans that had been previously reported only in East-Asian GWAS. Based on statistical evidence and linkage disequilibrium (LD) structure, we have curated and narrowed down the list of the most likely candidate causal variants for each region. Functional annotation using data from ENCODE filtered for PrCa cell lines and eQTL analysis demonstrated significant enrichment for overlap with bio-features within this set. By incorporating the novel risk variants identified here alongside the refined data for existing association signals, we estimate that these loci now explain ∼38.9% of the familial relative risk of PrCa, an 8.9% improvement over the previously reported GWAS tag SNPs. This suggests that a significant fraction of the heritability of PrCa may have been hidden during the discovery phase of GWAS, in particular due to the presence of multiple independent signals within the same regio

Crafts, consumers and consumption: Asian artisanal crafts and the marketing of exotica

In a globalizing and more integrated world economy, craft goods which are sourced from the developing world are increasingly becoming part of the decorative arrangement in first world households. While there has recently emerged detailed research on artisans and their integration into global markets, and on consumption more generally, there has been relatively little sociological research concerning the advertising and consumption of these artisanal products. In light of studies concerning the marketing of third world crafts, and based on content analysis of a number of web sites and catalogues marketing Asian crafts undertaken in 2004, this paper has two main aims. First, it analyses the various ways “ethnic branding” is an important marketing feature of a craft item and second, it aims to deconstruct the images and texts in terms of notions of “traditional”, “natural” and “authentic”. Underlying the analysis and interpretation is the notion of the commodification of poverty. The paper thus develops our understanding of the relationship between global markets, marketing of third world craft goods, and consumption practices

Globalisation and the middle classes in India: The social and cultural impact of neoliberal reforms

This book fills an important gap in the existing literature on economic liberalization and globalisation in India by providing much needed ethnographic data from those affected by neoliberal globalisation. Based on ethnographic fieldwork and interviews, it reveals the complexity of the globalisation process and describes and accounts for the contradictory attitudes of the lower middle classes. The authors challenge the notion of a homogeneous Indian middle class as being the undoubted beneficiaries of recent neoliberal economic reforms, showing that while the lower middle classes are generally supportive of the recent economic reforms, they remain doubtful about the long term benefits of the country's New Economic Policy and liberalisation. Significantly, this book discusses and analyzes both the economic and cultural sides to globalisation in India, providing much-needed data in relation to several dimensions including the changing costs of living; household expenditure, debt and consumerism; employment and workplace restructuring; gender relations and girls’ education; global media and satellite television; and the significance of English in a globalising India