Ultraviolet Cancellations in Half-Maximal Supergravity as a Consequence of the Double-Copy Structure

We show that the double-copy structure of gravity forbids divergences in pure half-maximal (16 supercharge) supergravity at four and five points at one loop in D<8 and at two loops in D<6. We link the cancellations that render these supergravity amplitudes finite to corresponding ones that eliminate forbidden color factors from the divergences of pure nonsupersymmetric Yang-Mills theory. The vanishing of the two-loop four-point divergence in D=5 half-maximal supergravity is an example where a valid counterterm satisfying the known symmetries exists, yet is not present. We also give explicit forms of divergences in half-maximal supergravity at one loop in D=8 and at two loops in D=6.Comment: 32 pages, revtex, 6 figures, v3 minor correction

Twenty Years of Searching for (and Finding) Globular Cluster Pulsars

Globular clusters produce orders of magnitude more millisecond pulsars per unit mass than the Galactic disk. Since the first cluster pulsar was uncovered twenty years ago, at least 138 have been identified - most of which are binary millisecond pulsars. Because of their origins involving stellar encounters, many of these systems are exotic objects that would never be observed in the Galactic disk. Examples include pulsar-main sequence binaries, extremely rapid rotators (including the current record holder), and millisecond pulsars in highly eccentric orbits. These systems are allowing new probes of the interstellar medium, the equation of state of material at supra-nuclear density, the mass distribution of neutron stars, and the dynamics of globular clusters.Comment: 9 pages, 6 figures. Submitted review for the "40 Years of Pulsars" conference in Montreal, Aug 2007. To be published by the AI

Orientation dependence of ferroelectric properties of pulsed-laser-ablated Bi4-xNdxTi3O12 films

Epitaxial (001)-, (118)-, and (104)-oriented Nd-doped Bi4Ti3O12 films have been grown by pulsed-laser deposition from a Bi4-xNdxTi3O12 (x=0.85) target on SrRuO3 coated single-crystal (100)-, (110)-, and (111)-oriented SrTiO3 substrates, respectively. X-ray diffraction illustrated a unique epitaxial relationship between film and substrate for all orientations. We observed a strong dependence of ferroelectric properties on the film orientation, with no ferroelectric activity in an (001)-oriented film; a remanent polarization 2P(r) of 12 muC/cm(2) and coercive field E-c of 120 kV/cm in a (118)-oriented film; and 2P(r)=40 muC/cm(2), E-c=50 kV/cm in a (104)-oriented film. The lack of ferroelectric activity along the c-axis is consistent with the orthorhombic nature of the crystal structure of the bulk material, as determined by powder neutron diffraction. (C) 2003 American Institute of Physics

Isogeometric B\'ezier dual mortaring: Refineable higher-order spline dual bases and weakly continuous geometry

In this paper we develop the isogeometric B\'ezier dual mortar method. It is based on B\'ezier extraction and projection and is applicable to any spline space which can be represented in B\'ezier form (i.e., NURBS, T-splines, LR-splines, etc.). The approach weakly enforces the continuity of the solution at patch interfaces and the error can be adaptively controlled by leveraging the refineability of the underlying dual spline basis without introducing any additional degrees of freedom. We also develop weakly continuous geometry as a particular application of isogeometric B\'ezier dual mortaring. Weakly continuous geometry is a geometry description where the weak continuity constraints are built into properly modified B\'ezier extraction operators. As a result, multi-patch models can be processed in a solver directly without having to employ a mortaring solution strategy. We demonstrate the utility of the approach on several challenging benchmark problems. Keywords: Mortar methods, Isogeometric analysis, B\'ezier extraction, B\'ezier projectio

On the Rotation Period of (90377) Sedna

We present precise, ~1%, r-band relative photometry of the unusual solar system object (90377) Sedna. Our data consist of 143 data points taken over eight nights in October 2004 and January 2005. The RMS variability over the longest contiguous stretch of five nights of data spanning nine days is only 1.3%. This subset of data alone constrain the amplitude of any long-period variations with period P to be A<1% (P/20 days)^2. Over the course of any given 5-hour segment, the data exhibits significant linear trends not seen in a comparison star of similar magnitude, and in a few cases these segments show clear evidence for curvature at the level of a few millimagnitudes per hour^2. These properties imply that the rotation period of Sedna is O(10 hours), cannot be 10 days, unless the intrinsic light curve has significant and comparable power on multiple timescales, which is unlikely. A sinusoidal fit yields a period of P=(10.273 +/- 0.002) hours and semi-amplitude of A=(1.1 +/- 0.1)%. There are additional acceptable fits with flanking periods separated by ~3 minutes, as well as another class of fits with P ~ 18 hours, although these later fits appear less viable based on visual inspection. Our results indicate that the period of Sedna is likely consistent with typical rotation periods of solar system objects, thus obviating the need for a massive companion to slow its rotation.Comment: 7 pages, 4 figures, 2.5 tables. Final ApJL version, minor changes. Full light curve data in tex

Anomalous quantum reflection of Bose-Einstein condensates from a silicon surface: the role of dynamical excitations

We investigate the effect of inter-atomic interactions on the quantum-mechanical reflection of Bose-Einstein condensates from regions of rapid potential variation. The reflection process depends critically on the density and incident velocity of the condensate. For low densities and high velocities, the atom cloud has almost the same form before and after reflection. Conversely, at high densities and low velocities, the reflection process generates solitons and vortex rings that fragment the condensate. We show that this fragmentation can explain the anomalously low reflection probabilities recently measured for low-velocity condensates incident on a silicon surface.Comment: 5 figures, 5 pages, references correcte

Leadership without Leaders? Starters and Followers in Online Collective Action

The Internet has been ascribed a prominent role in collective action, particularly with widespread use of social media. But most mobilisations fail. We investigate the characteristics of those few mobilisations that succeed and hypothesise that the presence of 'starters' with low thresholds for joining will determine whether a mobilisation achieves success, as suggested by threshold models. We use experimental data from public good games to identify personality types associated with willingness to start in collective action. We find a significant association between both extraversion and internal locus of control, and willingness to start, while agreeableness is associated with a tendency to follow. Rounds without at least a minimum level of extraversion among the participants are unlikely to be funded, providing some support for the hypothesis

B-cell maturation antigen (BCMA) in multiple myeloma: rationale for targeting and current therapeutic approaches.

Despite considerable advances in the treatment of multiple myeloma (MM) in the last decade, a substantial proportion of patients do not respond to current therapies or have a short duration of response. Furthermore, these treatments can have notable morbidity and are not uniformly tolerated in all patients. As there is no cure for MM, patients eventually become resistant to therapies, leading to development of relapsed/refractory MM. Therefore, an unmet need exists for MM treatments with novel mechanisms of action that can provide durable responses, evade resistance to prior therapies, and/or are better tolerated. B-cell maturation antigen (BCMA) is preferentially expressed by mature B lymphocytes, and its overexpression and activation are associated with MM in preclinical models and humans, supporting its potential utility as a therapeutic target for MM. Moreover, the use of BCMA as a biomarker for MM is supported by its prognostic value, correlation with clinical status, and its ability to be used in traditionally difficult-to-monitor patient populations. Here, we review three common treatment modalities used to target BCMA in the treatment of MM: bispecific antibody constructs, antibody-drug conjugates, and chimeric antigen receptor (CAR)-modified T-cell therapy. We provide an overview of preliminary clinical data from trials using these therapies, including the BiTE® (bispecific T-cell engager) immuno-oncology therapy AMG 420, the antibody-drug conjugate GSK2857916, and several CAR T-cell therapeutic agents including bb2121, NIH CAR-BCMA, and LCAR-B38M. Notable antimyeloma activity and high minimal residual disease negativity rates have been observed with several of these treatments. These clinical data outline the potential for BCMA-targeted therapies to improve the treatment landscape for MM. Importantly, clinical results to date suggest that these therapies may hold promise for deep and durable responses and support further investigation in earlier lines of treatment, including newly diagnosed MM