Administrative review mechanisms within the ECB

The single supervisory mechanism and the single resolution mechanism are the two main pillars of the European banking union. These complex frameworks encompass innovative quasi-judicial systems which allow undertakings and national authorities to contend certain decisions taken respectively by the ECB and the SRB, through two technical independent bodies, namely an Administrative Board of Review (ABoR) and an Appeal Panel. Through a comparison of the founding provisions of these two panels with other similar experiences in highly regulated technical sectors, it is argued that the current architecture of nonjudicial remedies available in the banking union is not set up as a single unitary model, but as an hybrid one with distinctive features adapted to the peculiarities of supervisory and recovery functions. It is questionable whether such characteristic may impair the position of private individuals and the ability to cope with the complex matters concerned in an effective way

Kaon physics with KLOE

Kaon physics can test new-physics effects in leptonic or semileptonic decays. A unitarity test of the first row of the CKM mixing matrix is obtained from the precision measurements of Kl3 widths for K{\pm}, KL, and (unique to KLOE) KS. The KLOE measurement of RK = {\Gamma}(Ke2)/{\Gamma}(K{\mu}2) with an accuracy at the % level, aims at finding evidence of deviations from the SM prediction induced by lepton-flavor violation new-physics effects.Comment: 8 pages, 2 figures, 1 table, proceedings of the La Thuile 2010 Conferenc

Mechanistic target of rapamycin (mTOR) activation during ruminant mammary development and function : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Animal Science at Massey University, Palmerston North, New Zealand

This thesis examines the abundance of total and activated mechanistic target of rapamycin (mTOR) pathway components in the developing and functional ruminant mammary gland. mTOR pathway activation is stimulated by a wide range of intra- and extracellular signals, such as amino acids (AA) and hormones, making the mTOR pathway a potential candidate for the development of intervention strategies designed to increase ruminant lactation potential. Tissues from two trials shown to improve lactation potential; dam-fetal nutrition and exogenous growth hormone (GH) administration during lactation, were used to measure changes in total and activated mTOR pathway protein abundance. Results show mammary glands of d 140 fetal lambs carried by maintenance fed dams and dairy cows administered exogenous GH, had increased abundance of total and activated mTOR and mitogen activated protein kinase (MAPK) pathway proteins. Increased abundance was associated with changes in biochemical indices. In the GH study MAPK pathway activation was stimulated by IGF-1 signaling whilst mTOR pathway activation was proposed to be mediated by AA signalling. Data from the GH study shows, L-arginine a known activator of the mTOR pathway, was the only AA reduced in both plasma and the lactating gland. Upstream factors were not identified for the phenotype observed in the dam-fetal nutrition study, but similar mechanisms were proposed. To elucidate the potential regulation of mTOR pathway activation by L-arginine and examine the effect on milk production, in vitro bovine cell culture models were evaluated. Results show that none of the models evaluated produced a lactating phenotype – a pre-requisite to accurately study the lactating gland in vitro. Finally, this thesis shows L-arginine administration from d 100 to d 140 of pregnancy, in twin bearing ewes had no effect on mTOR protein abundance or activation. However, administration from d 100 to parturition improved maternal gland health. In summary, this thesis associates improved lactation potential with increased total and activated mTOR pathway protein abundance, and the administration of L-arginine during late gestation with improved gland health. These findings provide fundamental knowledge that may lead to the development of novel technologies to increase ruminant gland performance and health

Negro sobre negro

Poema escrito entre los años de 1969 y 1979, traducido del Italiano por Guillermo Fernández y publicado en la revista "La Colmena" Núm. 42 del año 2004, de la Universidad Autónoma del Estado de México, en la sección "Italia en la Colmena

Parallel Deferred Update Replication

Deferred update replication (DUR) is an established approach to implementing highly efficient and available storage. While the throughput of read-only transactions scales linearly with the number of deployed replicas in DUR, the throughput of update transactions experiences limited improvements as replicas are added. This paper presents Parallel Deferred Update Replication (P-DUR), a variation of classical DUR that scales both read-only and update transactions with the number of cores available in a replica. In addition to introducing the new approach, we describe its full implementation and compare its performance to classical DUR and to Berkeley DB, a well-known standalone database

Impacts of radiative corrections on measurements of lepton flavour universality in B→DℓνℓB \to D \ell \nu_{\ell} decays

Radiative corrections to $B \to D \ell \nu_{\ell}$ decays may have an impact on predictions and measurements of the lepton flavour universality observables $\mathcal{R}(D^+)$ and $\mathcal{R}(D^0)$. In this paper, a comparison between recent calculations of the effect of soft-photon corrections on $\mathcal{R}(D^+)$ and $\mathcal{R}(D^0)$, and corrections generated by the widely used package PHOTOS is given. The impact of long-distance Coulomb interactions, which are not simulated in PHOTOS, is discussed. Furthermore, the effect of high-energy photon emission is studied through pseudo-experiments in an LHCb-like environment. It is found that over- or underestimating these emissions can cause a bias on $\mathcal{R}(D)$ as high as 7%. However, this bias depends on individual analyses, and future high precision measurements require an accurate evaluation of these QED corrections.Comment: 8 pages, 21 figures, published by EPJ