29 research outputs found

    Criticality of Low-Energy Protons in Single-Event Effects Testing of Highly-Scaled Technologies

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    We report low-energy proton and low-energy alpha particle single-event effects (SEE) data on a 32 nm silicon-on-insulator (SOI) complementary metal oxide semiconductor (CMOS) latches and static random access memory (SRAM) that demonstrates the criticality of using low-energy protons for SEE testing of highly-scaled technologies. Low-energy protons produced a significantly higher fraction of multi-bit upsets relative to single-bit upsets when compared to similar alpha particle data. This difference highlights the importance of performing hardness assurance testing with protons that include energy distribution components below 2 megaelectron-volt. The importance of low-energy protons to system-level single-event performance is based on the technology under investigation as well as the target radiation environment

    Low-Energy Proton Testing Methodology

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    Use of low-energy protons and high-energy light ions is becoming necessary to investigate current-generation SEU thresholds. Systematic errors can dominate measurements made with low-energy protons. Range and energy straggling contribute to systematic error. Low-energy proton testing is not a step-and-repeat process. Low-energy protons and high-energy light ions can be used to measure SEU cross section of single sensitive features; important for simulation

    RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients

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    Rheumatoid arthritis (RA) is a chronic inflammatory disorder with poorly defined aetiology characterised by synovial inflammation with variable disease severity and drug responsiveness. To investigate the peripheral blood immune cell landscape of early, drug naive RA, we performed comprehensive clinical and molecular profiling of 267 RA patients and 52 healthy vaccine recipients for up to 18 months to establish a high quality sample biobank including plasma, serum, peripheral blood cells, urine, genomic DNA, RNA from whole blood, lymphocyte and monocyte subsets. We have performed extensive multi-omic immune phenotyping, including genomic, metabolomic, proteomic, transcriptomic and autoantibody profiling. We anticipate that these detailed clinical and molecular data will serve as a fundamental resource offering insights into immune-mediated disease pathogenesis, progression and therapeutic response, ultimately contributing to the development and application of targeted therapies for RA.</p

    Proton-Induced Upsets in SLC and MLC NAND Flash Memories

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    We investigate proton-induced upsets in state-of-the-art NAND Flash memories, down to the 25-nm node. The most striking result is the opposite behavior of Multi-Level Cell (MLC) and Single-Level Cell (SLC) devices, in terms of floating gate error cross section as a function of proton energy. In fact, the cross section increases with proton energy in SLC whereas it decreases in MLC. The reason for this behavior is studied through comparison of heavy-ion data and device simulations. The main factors that determine proton energy dependence are discussed, such as the energy dependence of nuclear cross section between protons and chip materials, the LET, energy, and angular distributions of the generated secondaries, but also the heavy-ion and total dose response of the studied devices. Proton irradiation effects in the control circuitry of NAND Flash memories are shown as well
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