1,263 research outputs found
The tropospheric response pattern to solar activity forcing
It is tempting to speculate on the possibility that solar flares sometimes are the initial cause of and atmospheric disturbance, which cumulative effect may give rise to a correlation at the 11 year timescale. Reasons to reconsider the possible relevance of solar flare response studies are stated. The discovery of the apparently decisive role of the Quasi-Biennial Oscillations (QBO) in establishing the atmospheric response pattern to solar forcing may throw new light on some of the earlier published relations. Reanalysis of old data in some cases may be advisable. Data on solar flares and their effects on the earth's atmosphere might be a promising candidate for reexamination
Continuous blood pressure monitoring:The pulse of hemodynamics
Critical illnesses and surgical procedures can impede the continuous blood flow to vital organs, potentially resulting in inadequate oxygen supply to meet their metabolic demands. Monitoring tools to assess organ perfusion are not readily available at the patient's bedside. Therefore, blood pressure measurements currently serve as a surrogate to estimate a patient's circulatory state. The first part of this thesis offers an overview of how critically low arterial blood pressure, also known as hypotension, is defined, monitored, and treated in intensive care units (ICUs) across various countries worldwide. Additionally, it provides insight into the effects of hypotension exposure during an ICU stay on patient outcomes. To prevent hypotension-related organ injury, blood pressure is often continuously monitored in critically ill patients, allowing for immediate alarms and prompt treatment if hypotension occurs. However, hypotension, and therefore organ injury, already occurred at that point. Moreover, selecting the appropriate treatment can be challenging as the cause of the blood pressure drop may be unclear. The final part of this thesis focuses on the prediction and prevention of hypotensive events during cardiac surgery and postoperative intensive care unit stay using continuous blood pressure monitoring and machine learning
Convex relaxation of mixture regression with efficient algorithms
We develop a convex relaxation of maximum a posteriori estimation of a mixture of regression models. Although our relaxation involves a semidefinite matrix variable, we reformulate the problem to eliminate the need for general semidefinite programming. In particular, we provide two reformulations that admit fast algorithms. The first is a max-min spectral reformulation exploiting quasi-Newton descent. The second is a min-min reformulation consisting of fast alternating steps of closed-form updates. We evaluate the methods against Expectation-Maximization in a real problem of motion segmentation from video data
Definition and incidence of hypotension in intensive care unit patients, an international survey of the European Society of Intensive Care Medicine
Introduction: Although hypotension in ICU patients is associated with adverse outcome, currently used definitions are unknown and no universally accepted definition exists. Methods: We conducted an international, peer-reviewed survey among ICU physicians and nurses to provide insight in currently used definitions, estimations of incidence, and duration of hypotension. Results: Out of 1394 respondents (1055 physicians (76%) and 339 nurses (24%)), 1207 (82%) completed the questionnaire. In all patient categories, hypotension definitions were predominantly based on an absolute MAP of 65 mmHg, except for the neuro(trauma) category (75 mmHg, p < 0.001), without differences between answers from physicians and nurses. Hypotension incidence was estimated at 55%, and time per day spent in hypotension at 15%, both with nurses reporting higher percentages than physicians (estimated mean difference 5%, p = 0.01; and 4%, p < 0.001). Conclusions: An absolute MAP threshold of 65 mmHg is most frequently used to define hypotension in ICU patients. In neuro(trauma) patients a higher threshold was reported. The majority of ICU patients are estimated to endure hypotension during their ICU admission for a considerable amount of time, with nurses reporting a higher estimated incidence and time spent in hypotension than physicians.</p
The BeppoSAX WFC X-ray source catalogue
We present the catalogue of X-ray sources detected by the two Wide Field
Cameras (WFCs) in complete observations on board BeppoSAX during its 6 years of
operational lifetime, between April 1996 and April 2002. The BeppoSAX WFCs were
coded mask instruments sensitive in the 2-28 keV energy band with a 40x40
square degree fields of view, pointing in opposite directions and
perpendicularly to the BeppoSAX Narrow Field Instruments (NFI). The WFCs were
usually operated simultaneously to NFI observations, each lasting up to several
days. WFCs observed thus the entire sky several times with a typical
sensitivity of 2 to 10 mCrab. A systematic analysis of all WFC observations in
the BeppoSAX archive has been carried out using the latest post-mission release
of the WFC analysis software and calibrations. The catalogue includes 253
distinct sources, obtained from a total sample of 8253 WFC detections. We
describe the basic statistical properties of the sample and present a six-year
history of two celestial calibration X-ray sources.Comment: 15 pages, 11 figures, Catalogue, Accepted for publication on A&
Effect of spatial distribution of daily rainfall on interior catchment response of a distributed hydrological model
International audienceWe investigate the effect of spatial variability of daily rainfall on soil moisture, groundwater level and discharge using a physically-based, fully-distributed hydrological model. This model is currently in use with the district water board and is considered to represent reality. We focus on the effect of rainfall spatial variability on day-to-day variability of the interior catchment response, as well as on its effect on the general hydrological behaviour of the catchment. The study is performed in a flat rural catchment (135 km2) in the Netherlands, where the climate is semi-humid (average precipitation 800 mm/year, evapotranspiration 550 mm/year) and rainfall is predominantly stratiform (i.e. large scale). Both range-corrected radar data (resolution 2.5×2.5 km2) as well as data from a dense network of 30 raingauges are used, observed for the period March?October 2004. Eight different rainfall scenarios, either spatially distributed or spatially uniform, are used as input for the hydrological model. The main conclusions from this study are: (i) using a single raingauge as rainfall input carries a great risk for the prediction of discharge, groundwater level and soil moisture, especially if the raingauge is situated outside the catchment; (ii) taking into account the spatial variability of rainfall instead of using areal average rainfall as input for the model is needed to get insight into the day-to-day spatial variability of discharge, groundwater level and soil moisture content; (iii) to get insight into the general behaviour of the hydrological system it is sufficient to use correct predictions of areal average rainfall over the catchment
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