Quality of service at the computer networks based on internet

А framework for the emerging computer networks quality of Internet service is presented. Two important components of the framework are considered: integrated service and differentiated service. They are described and problems related to their implementation are discussed. Two broadly classified algorithms are investigated: scheduling and queue management algorithms. The model of the average time delay for the type packet is presented.Запропоновано структуру забезпечення якості надання послуг Internet. Розглянуто два важливі компоненти цієї структури: інтегроване та диференційоване обслуговування, їх реалізацію та пов’язані з нею проблеми. Досліджено два алгоритма: планування і управління чергою. Запропоновано модель даних, яка базується на теорії масового обслуговування.Предложена структура обеспечения качества предоставления услуг Internet. Рассмотрены два важных компонента этой структуры: интегрированное и дифференцированное обслуживание, их реализация и связанные с ней проблемы. Исследованы два алгоритма: планирования и управления очередью. Предложена модель данных, базирующаяся на теории массового обслуживания

Constructing knowledge: semantic memories in mice

Contains fulltext : 203521.pdf (publisher's version ) (Open Access)Radboud University, 17 juni 2019Promotor : Roozendaal, B. Co-promotores : Battaglia, F.P., Genzel, L.K.E

Using conditioned suppression to investigate compulsive drug seeking in rats

Item does not contain fulltextBACKGROUND: Persistent drug seeking despite harmful consequences is a defining characteristic of addiction. Recent preclinical studies have demonstrated the occurrence of this hallmark feature of addictive behaviour in rodents. For example, it has been shown that the ability of an aversive conditioned stimulus (CS) to suppress cocaine seeking was diminished after an extended self-administration history. The present study aimed to optimize the experimental conditions to examine conditioned suppression of sucrose and cocaine seeking in rats, and its dependence on the longevity of self-administration experience. METHODS: We investigated whether conditioned suppression depends on the intensity and quantity of footshocks during conditioning. In addition, the effects of CS omission, extinction and reconditioning were investigated, as well as the influence of the CS interval sequence on conditioned suppression. We also compared conditioned suppression after a limited and extended sucrose or cocaine self-administration history. RESULTS: We found that conditioned suppression depended on the intensity rather than the quantity of footshocks, whereby a higher footshock intensity was necessary to induce suppression of cocaine seeking compared to sucrose seeking. Conditioned suppression was most pronounced when the test started with presentation of the aversive CS, and conditioned suppression could be extinguished and reacquired. In addition, conditioned suppression of cocaine, but not sucrose seeking was reduced after extended self-administration experience. CONCLUSIONS: These data provide a detailed analysis of conditioned suppression of cocaine and sucrose seeking. Importantly, we confirm the usefulness of conditioned suppression to study persistent drug seeking after prolonged drug self-administration

The Object Space Task reveals increased expression of cumulative memory in a mouse model of Kleefstra syndrome

Contains fulltext : 222203.pdf (publisher's version ) (Open Access

The object space task shows cumulative memory expression in both mice and rats

Contains fulltext : 206128.pdf (publisher's version ) (Open Access)25 p

Glucocorticoid enhancement of recognition memory via basolateral amygdala-driven facilitation of prelimbic cortex interactions

Contains fulltext : 202805.pdf (publisher's version ) (Closed access

Dopamine enhances signal-to-noise ratio in cortical-brainstem encoding of aversive stimuli

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