737 research outputs found
Engaging the Youngest Readers with Shared Reading Experiences
This article explores Shared Reading as an instructional approach that mimics home reading experiences in a group setting for young children. The article includes information about how to use enlarged text as the teacher provides experiences with books that first focus on the meaning and enjoyment of the story and then shifts to how print works and conventions that enhance the meaning of the story. The importance of being able to see the print in enlarged text that allows the teacher to extend the read aloud experience to include viewing print in big books and charts establishing the beginnings of visual attention to letters, words, and punctuation is examined
Does a Joint Academic-Practitioner Review Reconcile Rigor and Relevance?
A substantial body of literature discusses the so-called rigor-relevance gap
in management science and possible ways of overcoming it. A frequently
advocated approach, in line with Gibbons, Limoges, Nowotny, Schwartz, and
Trow’s “Mode 2” idea of creating “hybrid fora,” is the introduction of joint
academic–practitioner review processes in management journals. In an empirical
case study of one of the oldest management journals in the world, the authors
show that the demands of academic and practitioner reviewers are hardly
compatible, and, to some extent, inversely correlated. In contrast to other
studies, here the authors show that the reason for the tension between
academics and practitioners with regard to this issue does not lie in
differences in the evaluation criteria of each group. Rather, the different
worldviews of academics and practitioners lead to different interpretations of
these criteria and a striking incongruence between the two groups’ ideas of
practical relevance
Linkage Evidence for a Two-Locus Inheritance of LQT-Associated Seizures in a Multigenerational LQT Family With a Novel KCNQ1 Loss-of-Function Mutation
Mutations in several genes encoding ion channels can cause the long-QT (LQT)
syndrome with cardiac arrhythmias, syncope and sudden death. Recently, mutations in
some of these genes were also identified to cause epileptic seizures in these patients, and
the sudden unexplained death in epilepsy (SUDEP) was considered to be the pathologic
overlap between the two clinical conditions. For LQT-associated KCNQ1 mutations, only
few investigations reported the coincidence of cardiac dysfunction and epileptic seizures.
Clinical, electrophysiological and genetic characterization of a large pedigree (n = 241
family members) with LQT syndrome caused by a 12-base-pair duplication in exon 8 of
the KCNQ1 gene duplicating four amino acids in the carboxyterminal KCNQ1 domain
(KCNQ1dup12; p.R360_Q361dupQKQR, NM_000218.2, hg19). Electrophysiological
recordings revealed no substantial KCNQ1-like currents. The mutation did not exhibit a
dominant negative effect on wild-type KCNQ1 channel function. Most likely, the mutant
protein was not functionally expressed and thus not incorporated into a heteromeric
channel tetramer. Many LQT family members suffered from syncopes or developed
sudden death, often after physical activity. Of 26 family members with LQT, seizures were
present in 14 (LQTplus seizure trait). Molecular genetic analyses confirmed a causative
role of the novel KCNQ1dup12 mutation for the LQT trait and revealed a strong link
also with the LQTplus seizure trait. Genome-wide parametric multipoint linkage analyses
identified a second strong genetic modifier locus for the LQTplus seizure trait in the
chromosomal region 10p14. The linkage results suggest a two-locus inheritance model
for the LQTplus seizure trait in which both the KCNQ1dup12 mutation and the 10p14
risk haplotype are necessary for the occurrence of LQT-associated seizures. The data
strongly support emerging concepts that KCNQ1 mutations may increase the risk of
epilepsy, but additional genetic modifiers are necessary for the clinical manifestation of
epileptic seizures
THE ASSOCIATION BETWEEN ANXIETY, DEPRESSION, AND KINESIOPHOBIA LEVELS IN ACLR PATIENTS
Athletes frequently report psychological distress as a factor in failure to return to sport following an ACL reconstruction (ACLR). To improve rehabilitation following ACLR it is necessary to determine the associations between anxiety, depression, and kinesiophobia throughout ACLR rehabilitation. Participants (n= 42) completed the State-Trait Anxiety Index prior to surgery, PROMIS anxiety and depression surveys at 6- and 12 months post-operation, and the Tampa Scale of Kinesiophobia-11 at 12 months post-operation. Greater anxiety and depression scores at 6 months were associated with greater anxiety and depression scores at 12 months. Greater anxiety and depression scores at 12 months were weakly associated with greater TSK-11 scores at 12 months. Greater pre-operative state and trait scores were associated with each other. Anxiety, depression, and fear of reinjury exist during the first 12 months of ACLR rehabilitation and should be addressed during formal rehabilitation.Master of Art
Recommended from our members
An Investigation of Criteria Used to Identify Artistically Gifted Children
The purpose of this study was to determine and investigate -the criteria used to identify artistically gifted children and attempt to determine their validity. Sources of data included interviews with art teachers, interviews with children in combination with observations, and observations of characteristics cited in the literature. With one exception, the criteria which these art teachers used to identify artistically gifted children correlate with criteria found in the literature. There appeared to be, however, some characteristics with which these art teachers were not familiar. One characteristic found in the literature was neither listed by these art teachers nor observed by the investigator. Results indicated that these art teachers may value different types of characteristics than the experts
Historical and regional particularities in the prevalence of traumatic events and posttraumatic stress disorder in East and West Germany
Background
Epidemiological research on the prevalence of traumatic events and PTSD has shown that there are significant differences between countries, due to their different history and socialization processes. In the case of Germany, this is particularly relevant. Germany was divided into two states from 1949 to 1990. This study examines the prevalence of traumatic events and PTSD in the formerly divided East and West Germany.
Methods
For the prevalence of traumatic events, we used data from four representative surveys (years 2005, 2007, 2008, and 2016) with a total of N = 9,200 respondents. For the analyses of PTSD prevalence, we used data from three representative surveys (years 2005, 2007, 2008) with a total of N = 6676 respondents. We compared different birth cohorts, persons living in the former West vs. East Germany, and the application of different diagnostic criteria using a chi-square test.
Results
The overall one-month prevalence rate for PTSD was 3.4% (3.0% for men and 3.8% for women). We found significant differences in the occurrence of traumatic events between genders, different age cohorts as well as between people who live in East and West Germany. Significant differences in the prevalence of PTSD can only be observed for different age cohorts. Most of the age effects are due to traumatic events related to World War II (WWII). Prevalence rates for PTSD were higher when the diagnostic criterions of the DSM-V were applied compared to the criterions of the DSM-IV.
Conclusions
Our data suggests that socio-political factors may need to be considered when accounting for differences in occurrence rates of traumatic events, but not for prevalence rates of PTSD, between East and West Germany. People who have experienced WW II have a higher risk of suffering from PTSD. Future epidemiological trauma research should take historical and regional peculiarities of countries into account
Correlation Functions and Coulomb Blockade of Interacting Fermions at Finite Temperature and Size
We present explicit expressions for the correlation functions of interacting
fermions in one dimension which are valid for arbitrary system sizes and
temperatures. The result applies to a number of very different strongly
correlated systems, including mesoscopic quantum wires, quantum Hall edges,
spin chains and quasi-one-dimensional metals. It is for example possible to
calculate Coulomb blockade oscillations from our expression and determine their
dependence on interaction strength and temperature. Numerical simulations show
excellent agreement with the analytical results.Comment: 10 pages in revtex format including 2 embedded figures (using epsf).
The latest complete postscript file is available from
http://fy.chalmers.se/~eggert/papers/corrfcn.ps or by request from
[email protected]
Methodological strategies in using home sleep apnea testing in research and practice
Purpose
Home sleep apnea testing (HSAT) has increased due to improvements in technology, accessibility, and changes in third party reimbursement requirements. Research studies using HSAT have not consistently reported procedures and methodological challenges. This paper had two objectives: (1) summarize the literature on use of HSAT in research of adults and (2) identify methodological strategies to use in research and practice to standardize HSAT procedures and information. Methods
Search strategy included studies of participants undergoing sleep testing for OSA using HSAT. MEDLINE via PubMed, CINAHL, and Embase with the following search terms: “polysomnography,” “home,” “level III,” “obstructive sleep apnea,” and “out of center testing.” Results
Research articles that met inclusion criteria (n = 34) inconsistently reported methods and methodological challenges in terms of: (a) participant sampling; (b) instrumentation issues; (c) clinical variables; (d) data processing; and (e) patient acceptability. Ten methodological strategies were identified for adoption when using HSAT in research and practice. Conclusions
Future studies need to address the methodological challenges summarized in this paper as well as identify and report consistent HSAT procedures and information
- …