Apresentação

Já há algum tempo, vem sendo desenvolvido um número crescente de pesquisas no campo educacional na perspectiva dos estudos foucaultianos que se caracterizam, na maioria das vezes, por abordarem de modo inovador temas de relevância no cenário contemporâneo. Em especial, diversos pesquisadores vêm utilizando o conceito de biopolítica como uma potente lente teórico-metodológica, capaz de engendrar instigantes possibilidades de pesquisa. As teorizações foucaultianas acerca da biopolítica permitem novas e desafiadoras análises e problematizações de nossa história e de nosso presente, em particular no campo da pesquisa em Educação. A partir destas teorizações, é possível abordar temas recorrentes nas discussões educacionais atuais sob novos ângulos, de modo a desnaturalizar e desestabilizar certezas e verdades já arraigadas, produzindo dissonâncias nos modos de pensar a Educação

Catalogue of tree microhabitats : Reference field list

The present catalogue is one of the outputs of the demonstration project ‘Establishing a European network of demonstration sites for the integration of biodiversity conservation into forest management ..

Katalog over mikrohabitater på traeer: Referenceliste til feltbrug

This Integrate+ Technical Paper (in Danish) is one of several translations of the original published in English language (Catalogue of tree microhabitats – Reference field list)

LRPAP1 autoantibodies in mantle cell lymphoma are associated with superior outcome

Low-density lipoprotein (LDL) receptor-related protein-associated protein 1 (LRPAP1) had been identified by B-cell receptor (BCR) expression cloning and subsequent protein array screening as a frequent and proliferation-inducing autoantigen of mantle cell lymphoma (MCL). Of interest, high-titered and light chain-restricted LRPAP1 autoantibodies were detected in 8 of 28 patients with MCL. In the present study, LRPAP1 autoantibodies in sera of patients treated within the Younger and Elderly trials of the European MCL Network were analyzed regarding frequency, association with disease characteristics, and prognostic impact. LRPAP1 autoantibodies were detected in 41 (13%) of 312 evaluable patients with MCL. These LRPAP1 autoantibodies belonged predominantly to the immunoglobulin G (IgG) class and were clonally light chain restricted (27 with kappa light chains, 14 patients with lambda light chains). Titers ranged between 1:400 and 1:3200. The presence of LRPAP1 autoantibodies was not significantly associated with any baseline clinical characteristic, however, it was associated with a superior 5-year probability for failure-free survival (FFS) of 70% (95% confidence interval [CI], 57% to 87%) vs 51% (95% CI, 44% to 58%), P = .0052; and for overall survival (OS) of 93% (95% CI, 85% to 100%) vs 68% (95% CI, 62% to 74%), P = .0142. LRPAP1-seropositive patients had a Mantle Cell Lymphoma International Prognostic Index-adjusted hazard ratio for FFS of 0.48 (95% CI 0.27-0.83, P = .0083) and for OS of 0.47 (95% CI 0.24-0.94, P = .032). LRPAP1 autoantibodies were frequently detected in a large cohort of MCL patients treated within prospective multicenter clinical trials. Our results suggest better outcomes for LRPAP1-autoantibody seropositive patients

Marteloscopes as training tools for the retention and conservation of habitat trees in forests

Recently several initiatives on the political and practical level have aimed at promoting forest biodiversity and at halting the loss of species in forest ecosystems. Nevertheless numerous species are still threatened. The main reason for this phenomenon is most likely the fact that habitat trees – i.e. trees providing microhabitats for various different species – are rare in managed forests. In the course of the projects Integrate and Integrate+ (carried out at the European Forest Institute between 2011 and 2017) we looked for methods on how to retain habitat trees within the scope of integrative forest management. It became more and more apparent that most foresters very successfully recognize economically valuable trees, but not habitat trees. For that reason we categorized habitat structures occurring on trees and developed a microhabitat catalogue to determine habitat values. Additionally we used marteloscopes as training tools for the retention of habitat trees within integrative forest management. Altogether we established 40 such marteloscopes with a biodiversity focus across Europe. Three of these are located in Switzerland. Using a mobile app on a tablet computer we analyzed effects of different tree selections with respect to habitat and economic value of a stand. Furthermore the marteloscopes are ideal tools to convince decision makers or conservationists that harvesting trees and promoting biodiversity can be achieved in the very same stand

Catalogue of tree microhabitats: Reference field list

The present catalogue is one of the outputs of the demonstration project ‘Establishing a European network of demonstration sites for the integration of biodiversity conservation into forest management ..