18 research outputs found
Cold inelastic collisions between lithium and cesium in a two-species magneto-optical trap
We investigate collisional properties of lithium and cesium which are
simultaneously confined in a combined magneto-optical trap. Trap-loss
collisions between the two species are comprehensively studied. Different
inelastic collision channels are identified, and inter-species rate
coefficients as well as cross sections are determined. It is found that loss
rates are independent of the optical excitation of Li, as a consequence of the
repulsive Li-Cs interaction. Li and Cs loss by inelastic inter-species
collisions can completely be attributed to processes involving optically
excited cesium (fine-structure changing collisions and radiative escape). By
lowering the trap depth for Li, an additional loss channel of Li is observed
which results from ground-state Li-Cs collisions changing the hyperfine state
of cesium.Comment: submitted to Euro. Phys. J. D, special issue on Laser Cooling and
Trappin
Autler-Townes splitting in two-color photoassociation of 6Li
We report on high-resolution two-color photoassociation spectroscopy in the
triplet system of magneto-optically trapped 6Li. The absolute transition
frequencies have been measured. Strong optical coupling of the bound molecular
states has been observed as Autler-Townes splitting in the photoassociation
signal. The spontaneous bound-bound transition rate is determined and the
molecule formation rate is estimated. The observed lineshapes are in good
agreement with the theoretical model.Comment: 5 pages, 4 figures, accepted for publication in Phys. Rev. A (Rapid
Communication
Saturation of Cs2 Photoassociation in an Optical Dipole Trap
We present studies of strong coupling in single-photon photoassociation of
cesium dimers using an optical dipole trap. A thermodynamic model of the trap
depletion dynamics is employed to extract absolute rate coefficents. From the
dependence of the rate coefficient on the photoassociation laser intensity, we
observe saturation of the photoassociation scattering probability at the
unitarity limit in quantitative agreement with the theoretical model by Bohn
and Julienne [Phys. Rev. A, 60, 414 (1999)]. Also the corresponding power
broadening of the resonance width is measured. We could not observe an
intensity dependent light shift in contrast to findings for lithium and
rubidium, which is attributed to the absence of a p or d-wave shape resonance
in cesium
Saturation in heteronuclear photoassociation of 6Li7Li
We report heteronuclear photoassociation spectroscopy in a mixture of
magneto-optically trapped 6Li and 7Li. Hyperfine resolved spectra of the
vibrational level v=83 of the singlet state have been taken up to intensities
of 1000 W/cm^2. Saturation of the photoassociation rate has been observed for
two hyperfine transitions, which can be shown to be due to saturation of the
rate coefficient near the unitarity limit. Saturation intensities on the order
of 40 W/cm^2 can be determined.Comment: 5 pages, 3 figures, to appear in Phys. Rev. A (Rapid Communication
Formation of ultracold LiCs molecules
We present the first observation of ultracold LiCs molecules. The molecules
are formed in a two-species magneto-optical trap and detected by two-photon
ionization and time-of-flight mass spectrometry. The production rate
coefficient is found to be in the range 10^{-18}\unit{cm^3s^{-1}} to
10^{-16}\unit{cm^3s^{-1}}, at least an order of magnitude smaller than for
other heteronuclear diatomic molecules directly formed in a magneto-optical
trap.Comment: 8 pages, 2 figure
Continuous loading of a magnetic trap
We have realized a scheme for continuous loading of a magnetic trap (MT).
^{52}Cr atoms are continuously captured and cooled in a magneto-optical trap
(MOT). Optical pumping to a metastable state decouples atoms from the cooling
light. Due to their high magnetic moment (6 Bohr magnetons), low-field seeking
metastable atoms are trapped in the magnetic quadrupole field provided by the
MOT. Limited by inelastic collisions between atoms in the MOT and in the MT, we
load 10^8 metastable atoms at a rate of 10^8 atoms/s below 100 microkelvin into
the MT. After loading we can perform optical repumping to realize a MT of
ground state chromium atoms.Comment: 4 pages, 4 figures, version 2, modified references, included
additional detailed information, minor changes in figure 3 and in tex
Sympathetic Cooling with Two Atomic Species in an Optical Trap
We simultaneously trap ultracold lithium and cesium atoms in an optical
dipole trap formed by the focus of a CO laser and study the exchange of
thermal energy between the gases. The cesium gas, which is optically cooled to
K, efficiently decreases the temperature of the lithium gas through
sympathetic cooling. The measured cross section for thermalizing
Cs-Li collisions is cm, for both species in
their lowest hyperfine ground state. Besides thermalization, we observe
evaporation of lithium purely through elastic cesium-lithium collisions
(sympathetic evaporation).Comment: 4 pages 3 fig
Large atom number dual-species magneto-optical trap for fermionic 6Li and 40K atoms
We present the design, implementation and characterization of a dual-species
magneto-optical trap (MOT) for fermionic 6Li and 40K atoms with large atom
numbers. The MOT simultaneously contains 5.2x10^9 6Li-atoms and 8.0x10^9
40K-atoms, which are continuously loaded by a Zeeman slower for 6Li and a
2D-MOT for 40K. The atom sources induce capture rates of 1.2x10^9 6Li-atoms/s
and 1.4x10^9 40K-atoms/s. Trap losses due to light-induced interspecies
collisions of ~65% were observed and could be minimized to ~10% by using low
magnetic field gradients and low light powers in the repumping light of both
atomic species. The described system represents the starting point for the
production of a large-atom number quantum degenerate Fermi-Fermi mixture
Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
BACKGROUND:
Patients with atherosclerotic vascular disease remain at high risk for cardiovascular events despite effective statin-based treatment of low-density lipoprotein (LDL) cholesterol levels. The inhibition of cholesteryl ester transfer protein (CETP) by anacetrapib reduces LDL cholesterol levels and increases high-density lipoprotein (HDL) cholesterol levels. However, trials of other CETP inhibitors have shown neutral or adverse effects on cardiovascular outcomes.
METHODS:
We conducted a randomized, double-blind, placebo-controlled trial involving 30,449 adults with atherosclerotic vascular disease who were receiving intensive atorvastatin therapy and who had a mean LDL cholesterol level of 61 mg per deciliter (1.58 mmol per liter), a mean non-HDL cholesterol level of 92 mg per deciliter (2.38 mmol per liter), and a mean HDL cholesterol level of 40 mg per deciliter (1.03 mmol per liter). The patients were assigned to receive either 100 mg of anacetrapib once daily (15,225 patients) or matching placebo (15,224 patients). The primary outcome was the first major coronary event, a composite of coronary death, myocardial infarction, or coronary revascularization.
RESULTS:
During the median follow-up period of 4.1 years, the primary outcome occurred in significantly fewer patients in the anacetrapib group than in the placebo group (1640 of 15,225 patients [10.8%] vs. 1803 of 15,224 patients [11.8%]; rate ratio, 0.91; 95% confidence interval, 0.85 to 0.97; P=0.004). The relative difference in risk was similar across multiple prespecified subgroups. At the trial midpoint, the mean level of HDL cholesterol was higher by 43 mg per deciliter (1.12 mmol per liter) in the anacetrapib group than in the placebo group (a relative difference of 104%), and the mean level of non-HDL cholesterol was lower by 17 mg per deciliter (0.44 mmol per liter), a relative difference of -18%. There were no significant between-group differences in the risk of death, cancer, or other serious adverse events.
CONCLUSIONS:
Among patients with atherosclerotic vascular disease who were receiving intensive statin therapy, the use of anacetrapib resulted in a lower incidence of major coronary events than the use of placebo. (Funded by Merck and others; Current Controlled Trials number, ISRCTN48678192 ; ClinicalTrials.gov number, NCT01252953 ; and EudraCT number, 2010-023467-18 .)