571 research outputs found
Automatic Phonetic Transcription of Non-Prompted Speech
A reliable method for automatic phonetic transcription of non− prompted German speech has been developed at th
European surveillance of infections in cancer patients - ESIC
Major advances in cancer therapy result from development of multidrug chemotherapy regimens. Besides death from tumor progression, infections are currently one of the major causes of mortality and morbidity. Because of the risk of complications and mortality, the treatment for febrile neutropenia is admission to hospital and administration of broad-spectrum antibiotics. Response rates of initial antimicrobial treatment vary considerably (40-92%). Due to the heterogeneity of populations in randomized studies, comparison of efficacy and identification of risk factors is limited. This is the main reason why the European Society of Biomodulation and Chemotherapy (ESBiC) is conducting a surveillance study that concentrates more on the evaluation of risk factors than on the therapeutic outcome of prospective randomized antimicrobial regimens: European Surveillance of Infections in Cancer Patients (ESIC). The present contribution is to determine which cancer patients are at low risk for fever, and can benefit from first-line treatment with treatment options such as monotherapy as well as on an outpatient basis
Genera
Diplomarbeit „Genera“ Ralph J. Schiel Erstbetreuung: Professor Bernd Jahnke Co-Betreuung: Andreas Bechtold Kommunikationsdesign HTWG Konstanz, SS 2003 Thema Die Diplomarbeit „Genera“ beschäftigt sich mit Interaktions- und Interfacedesign für eine Multimedia Home Plattform (MHP). Diese Plattform stellt eine Verbindung von Internet, Radio,TV, LAN-Netzwerken, , Computer, Hi-Fi und Telefonanlage dar. Die Entwicklung geht hierbei weg von verschiedenen Medien mit unterschiedlichsten Formaten, hin zu einer einzigen Gerätschaft, welche alle Komponenten beinhaltet. Am Beispiel des multimedialen Computerspiels „Genera“ wird eine zukünftige Nutzungsform dieses Mediums aufgezeigt. Tragende Elemente sind hierbei Film, Videospiel, Videoclips, Media Art, Internet und Hyperstrukturen. Die Einsatzbereiche liegen u.a. in den Bereichen Bildung, Wissenschaft und Forschung, Projekt Management und Unterhaltung. Der Benutzer eignet sich Kompetenzen bezüglich innovativer Nutzungs- und Kombinationsformen von Medien an. Durch verant-wortungsvolles Informations Knowledge und - Management erhält er die nötigen Voraussetzungen, um im stattfindenden Digital Devide bestehen zu können. Der Benutzer interagiert in den zunehmend verschmelzenden Dimensionen von Realität und Virtualität
The Palgrave handbook of global slavery throughout history
This open access handbook takes a comparative and global approach to analyse the practice of slavery throughout history. To understand slavery - why it developed, and how it functioned in various societies – is to understand an important and widespread practice in world civilisations. With research traditionally being dominated by the Atlantic world, this collection aims to illuminate slavery that existed in not only the Americas but also ancient, medieval, North and sub-Saharan African, Near Eastern, and Asian societies. Connecting civilisations through migration, warfare, trade routes and economic expansion, the practice of slavery integrated countries and regions through power-based relationships, whilst simultaneously dividing societies by class, race, ethnicity and cultural group. Uncovering slavery as a globalising phenomenon, the authors highlight the slave-trading routes that crisscrossed Africa, helped integrate the Mediterranean world, connected Indian Ocean societies and fused the Atlantic world. Split into five parts, the handbook portrays the evolution of slavery from antiquity to the contemporary era and encourages readers to realise similarities and differences between various manifestations of slavery throughout history. Providing a truly global coverage of slavery, and including thematic injections within each chronological part, this handbook is a comprehensive and transnational resource for all researchers interested in slavery, the history of labour, and anthropology.Cities, Migration and Global Interdependence 1350-200
Syntaxin 16 is a master recruitment factor for cytokinesis
Recently it was shown that both recycling endosome and endosomal sorting complex required for transport (ESCRT) components are required for cytokinesis, in which they are believed to act in a sequential manner to bring about secondary ingression and abscission, respectively. However, it is not clear how either of these complexes is targeted to the midbody and whether their delivery is coordinated. The trafficking of membrane vesicles between different intracellular organelles involves the formation of soluble N-ethylmaleiÂmide–sensitive factor attachment protein receptor (SNARE) complexes. Although membrane traffic is known to play an important role in cytokinesis, the contribution and identity of intracellular SNAREs to cytokinesis remain unclear. Here we demonstrate that syntaxin 16 is a key regulator of cytokinesis, as it is required for recruitment of both recycling endosome–associated Exocyst and ESCRT machinery during late telophase, and therefore that these two distinct facets of cytokinesis are inextricably linked
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Novel uses of a wide beam saddle field ion source for producing targets used in nuclear physics experiments at the Argonne National Laboratory ATLAS facility
The wide beam ion sputter source has several unique characteristics which make it very useful for producing, reducing the thickness or cleaning the surface of targets needed for nuclear physics experiments. A discussion of these techniques as well as the sputter source characteristics will be given. Sputter yields obtained utilizing the source are presented for a variety of materials common to nuclear target production
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