A Terrible Prank Gone Horribly Wrong the Development of Delusional Infestation as an Adjustment Reaction to a Traumatic Hoax

Delusional infestation (DI) is a somatic type delusional disorder, characterized by a fixed belief that one is infested by living or nonliving pathogens (1,3) . DI is a relatively rare disorder (4,5), with an estimated 20-80 cases per million people annually (6). Effective management of patients suffering from DI is crucial, as patients may cause significant harm to themselves in their attempts to remove the pathogens (7,8). Regarding treatment options, antipsychotic medications such as pimozide and risperidone have been promising (8,10). However, there remain many barriers to care (11), and patients are hardly ever seen in psychiatry as they preferably seek other specialists such as dermatologists (7,11). It is important for psychiatrists to understand this devastating disorder and properly manage and treat patients with DI when the opportunity arises

Spot the Signs- 防范未然，及时干预- 培训

Opiate overdose is an unfortunately common risk factor for suicide; suicide attempts accounted for an estimated 30% of fatal opioid overdoses during the pandemic, and patients with an episode of opiate overdose were at an 18 times higher risk of suicide in the following year. As a result, the Rowan School of Osteopathic Medicine Department of Psychiatry developed an Integrated Mental Health Awareness and Suicide Prevention program targeted at members of the community and frontline workers to increase awareness and provide brief interventions, which demonstrated an improvement of 89% in our English-speaking attendees. Chinese is the second-most common non-English language in New Jersey, with an estimated 120 thousand speakers, and major Chinatowns in the adjacent cities of New York City and Philadelphia. Chinese patients also frequently experience culturally bound stigmas and symptoms, so it is vital to ensure content is appropriately targeted for maximum impact. In this poster, we showcase some examples of translated and targeted content, and detail several terms that differ between dialects or regional varieties commonly spoken in New Jersey. Attention to matching dialect and the use of local terminology for culturally specific syndromes can increase effectiveness of patient education programs in underserved populations.The use of qualified human medical translators proficient in the dialect spoken by specific patients or provider-patient concordance also prevents misunderstanding and may improve rapport

Glycan labeling strategies and their use in identification and quantification

Most methods for the analysis of oligosaccharides from biological sources require a glycan derivatization step: glycans may be derivatized to introduce a chromophore or fluorophore, facilitating detection after chromatographic or electrophoretic separation. Derivatization can also be applied to link charged or hydrophobic groups at the reducing end to enhance glycan separation and mass-spectrometric detection. Moreover, derivatization steps such as permethylation aim at stabilizing sialic acid residues, enhancing mass-spectrometric sensitivity, and supporting detailed structural characterization by (tandem) mass spectrometry. Finally, many glycan labels serve as a linker for oligosaccharide attachment to surfaces or carrier proteins, thereby allowing interaction studies with carbohydrate-binding proteins. In this review, various aspects of glycan labeling, separation, and detection strategies are discussed