Sport for All? Insight into stratification and compensation mechanisms of sporting activity in the 27 European Union member states

Physical activity is an important public health issue and the benefits of an active lifestyle in relation to well-being and health have been strongly emphasised in recent years in Europe, as well as in most parts of the world. However, previous research has shown that physical activity within Europe and its member states is stratified. The present article gains insight into: (1) the geographical stratification; and (2) the social stratification of physical activity in the 27 European Union member states in 2005. Special attention is given to sporting activity in comparison to other forms of physical activity (transport, occupation and household). By doing this we intend to develop a picture of physical activity, in particular sporting activity, within the European Union. In addition, we want to verify whether low sporting activity levels are counterbalanced by other pieces of the total 'menu of physical activities'. Based on Eurobarometer data from 2005 (N=26,688), bivariate analyses show that 4 out of 10 Europeans are not exposed to sporting activity. Moreover, particular subgroups of non-sportive citizens could be distinguished: South and East Europeans, and women, the elderly, individuals with a lower educational level and rural citizens. Our hypothesis that these groups would compensate for their non-sporting activity by being physically active in other domains could only be confirmed for women and rural citizens, in particular with regard to household physical activity. To understand the underlying structure of these possible compensation mechanisms, additional quantitative and qualitative research is needed. Nevertheless, because of societal trends towards an inactive society, the role of sporting activity will be increasingly important in the future for all inactive subgroups. For this purpose, not only should necessary resources and key stakeholders be identified, but also more importantly the social and environmental barriers for sporting activity need to be addressed

Evolution of experimental design and research techniques in HIV-1 reservoir studies : a systematic review

Although HIV-1 has evolved from a deadly to a chronic disease over the past 20 years, an HIV-1 cure is still lacking due to the presence of persisting cellular viral reservoirs which are spread throughout the body in different anatomical compartments. Hence, the identification and characterization of these HIV-1 reservoirs were the focus of many studies during the past decades. In this review, a systematic literature screening and text mining approach were implemented to assess the evolution in experimental design of these HIV-1 reservoir studies. For this purpose. the online databases PubMed, Web of Science. and ClinicalTrials.gov were consulted and 1768 articles were identified, of which 106 are included in this review. We observed several evolutions that indicate a more structured approach of recent HIV-1 reservoir studies. This includes the use of well-characterized patient cohorts, tissue sampling at several time points and anatomical compartments, the inclusion of patients with different treatment status (on and off antiretroviral therapy), and the implementation of state-of-the-art research techniques such as single genome sequencing. In addition, there is an increased interest and sampling of lymphoid tissues and cerebrospinal fluid together with methods to investigate cellular subsets and HIV-1 sequences. Overall, this review describes an observed shift from detecting and quantifying HIV-1 toward a qualitative in-depth assessment of anatomical reservoirs and cellular subsets playing a role in H1V-1 persistence/latency. These trends coincide with the evolution in focus from controlling HIV-1 replication by currently available antiretroviral therapy toward HIV-1 curative strategies

Equilibrium of a Brownian particle with coordinate dependent diffusivity and damping: Generalized Boltzmann distribution

Fick's law for coordinate dependent diffusivity is derived. Corresponding diffusion current in the presence of coordinate dependent diffusivity is consistent with the form as given by Kramers-Moyal expansion. We have obtained the equilibrium solution of the corresponding Smoluchowski equation. The equilibrium distribution is a generalization of the Boltzmann distribution. This generalized Boltzmann distribution involves an effective potential which is a function of coordinate dependent diffusivity. We discuss various implications of the existence of this generalized Boltzmann distribution for equilibrium of systems with coordinate dependent diffusivity and damping.Comment: 11 pages, 1 figur

Vlaanderen binnen het Europese sportlandschap: een crossnationale analyse van sportbeoefening in de Europese Unie

A

For the eye altering, alters the all

C