141 research outputs found
Initial intramuscular perfusion pressure predicts early skeletal muscle function following isolated tibial fractures
<p>Abstract</p> <p>Background</p> <p>The severity of associated soft tissue trauma in complex injuries of the extremities guides fracture treatment and decisively determines patient's prognosis. Trauma-induced microvascular dysfunction and increased tissue pressure is known to trigger secondary soft tissue damage and seems to adversely affect skeletal muscle function.</p> <p>Methods</p> <p>20 patients with isolated tibial fractures were included. Blood pressure and compartment pressure (anterior and deep posterior compartment) were measured continuously up to 24 hours. Corresponding perfusion pressure was calculated. After 4 and 12 weeks isokinetic muscle peak torque and mean power of the ankle joint in dorsal and plantar flexion were measured using a Biodex dynamometer.</p> <p>Results</p> <p>A significant inverse correlation between the anterior perfusion pressure at 24 hours and deficit in dorsiflexion at 4 weeks was found for both, the peak torque (R = -0.83; p < 0.01) and the mean power (R = -0.84; p < 0.01). The posterior perfusion pressure at 24 h and the plantar flexion after 4 weeks in both, peak torque (R = -0.73, p =< 0.05) and mean power (R = -0.7, p =< 0.05) displayed a significant correlation.</p> <p>Conclusion</p> <p>The functional relationship between the decrease in intramuscular perfusion pressures and muscle performance in the early rehabilitation period indicate a causative and prognostic role of early posttraumatic microcirculatory derangements and skeletal muscle function. Therapeutic concepts aimed at effective muscle recovery, early rehabilitation, and decreased secondary tissue damage, should consider the maintenance of an adequate intramuscular perfusion pressure.</p
Time course of skeletal muscle regeneration after severe trauma: Muscle function against the background of MRI and histological findings
The effect of intermittent cryotherapy on the activities of citrate synthase and lactate dehydrogenase in regenerating skeletal muscle
Chirurgische Behandlungsergebnisse bei primären Tumoren und solitären Metastasen der Skapula
Untersuchung der klinischen Wirksamkeit der winkelstabilen Verriegelung in der intramedullären Nagelung bei Patienten mit distalen Tibiafrakturen: eine multizentrische, randomisiert-kontrollierte Studie
Die winkelstabile Plattenosteosynthese bei distalen intraartikulären Humerusfrakturen: Erste Ergebnisse mit dem Locking Compression Plate (LCP) System für den distalen Humerus
Analyse der Ionenkonzentration und klinischen Ergebnisse nach primärer Hüftgelenksendoprothetik mit Metall/Metall-Gleitpaarung: 10 Jahres Follow-up Studie
Die operative Versorgung distaler Radiusfrakturen mit winkelstabilen Platten: klinische und radiologische Ergebnisse
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