Osse Sky Survey Observations for Cycles Three Extreme Red Egret Blazars

The original purpose of this work was to probe EGRET sources of low significance, and to use statistical techniques to construct a log N - log S of sources at greater than 50 MeV. At this writing, the detection significance of EGRET sources is still an issue. Therefore, we shifted our focus to the known EGRET detections. These came in two groups: (a) the known blazars; and (b) the high-Galactic latitude EGRET sources not identified with optical (or radio) counterparts

Identifications of Einstein Slew Survey sources

The status of identifications of the Einstien Slew Survey, a bright soft x-ray catalog with 550 new x-ray sources, is discussed. Possible counterparts were found for greater than 95 percent of the Slew Survey based on positional coincidences and color-color diagnostics. The survey will be fully identified via upcoming radio and optical observations

Einstein Slew Survey: Data analysis innovations

Several new methods were needed in order to make the Einstein Slew X-ray Sky Survey. The innovations which enabled the Slew Survey to be done are summarized. These methods included experimental approach to large projects, parallel processing on a LAN, percolation source detection, minimum action identifications, and rapid dissemination of the whole data base

Pulmonary function evaluation during and following Skylab space flights

Previous experience during the Apollo postflight exercise testing indicated no major changes in pulmonary function. Although pulmonary function has been studied in detail following exposure to hypoxic and hyperoxic environments, few studies have dealt with normoxic environments at reduced total pressure as encountered during the Skylab missions. Forced vital capacity was measured during the preflight and postflight periods of the Skylab 2 mission. Initial in-flight measurements of vital capacity were obtained during the last two weeks of the second manned mission (Skylab 3). Comprehensive pulmonary function screening was accomplished during the Skylab 4 mission. The primary measurements made during Skylab 4 testing included residual volume determination, closing volume, vital capacity, and forced vital capacity and its derivatives. In addition, comprehensive in-flight vital capacity measurements were made during the Skylab 4 mission. Vital capacity was decreased slightly during flight in all Skylab 4 crewmen. No major preflight to postflight changes were observed in the other parameters

Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors.

Tyrphostins are a group of low molecular weight synthetic inhibitors of protein tyrosine kinases (PTK). The intracellular domains of the receptors for epidermal growth factor (EGF), transforming growth factor-alpha (TGF-alpha), insulin-like growth factor 1 (IGF-1) possess PTK activity. Since EGF, TGF-alpha and IGF-1 are considered to play an important role in the proliferation of pancreatic cancer cells, we studied the effects of tyrphostins on the growth of three human pancreatic cancer cell lines (MiaPaCa-2, Panc-1 and CAV). The tyrphostins AG17, T23 and T47 all inhibited EGF and serum-stimulated DNA synthesis. AG17 was found to be the most potent of these agents and caused a dose-dependent but reversible inhibition of cell growth. Furthermore using an immunoblotting procedure we also found AG17 to inhibit EGF-induced tyrosine phosphorylation in the MiaPaCa-2 cell line. Tyrosine kinase inhibitors may prove to be useful agents for the treatment of pancreatic cancer

Reinventing College Physics for Biologists: Explicating an epistemological curriculum

The University of Maryland Physics Education Research Group (UMd-PERG) carried out a five-year research project to rethink, observe, and reform introductory algebra-based (college) physics. This class is one of the Maryland Physics Department's large service courses, serving primarily life-science majors. After consultation with biologists, we re-focused the class on helping the students learn to think scientifically -- to build coherence, think in terms of mechanism, and to follow the implications of assumptions. We designed the course to tap into students' productive conceptual and epistemological resources, based on a theoretical framework from research on learning. The reformed class retains its traditional structure in terms of time and instructional personnel, but we modified existing best-practices curricular materials, including Peer Instruction, Interactive Lecture Demonstrations, and Tutorials. We provided class-controlled spaces for student collaboration, which allowed us to observe and record students learning directly. We also scanned all written homework and examinations, and we administered pre-post conceptual and epistemological surveys. The reformed class enhanced the strong gains on pre-post conceptual tests produced by the best-practices materials while obtaining unprecedented pre-post gains on epistemological surveys instead of the traditional losses.Comment: 35 pages including a 15 page appendix of supplementary material

Thirteen new BL Lacertae objects discovered by an efficient x ray/radio/optical technique

The discovery of 13 serendipitous BL Lac objects in the Einstein IPC Slew Survey by means of x ray/radio vs. x ray/optical color-color diagrams and confirmation by optical spectroscopy are reported. These 13 BL Lacs were discovered using a technique which exploits the characteristic broad band spectra of BL Lacs. New VLA detections provide accurate fluxes (f(6 cm) is approximately 0.5 mJy) and 2 in. positions, facilitating the determination of an optical counterpart. All 13 new BL Lacs show essentially featureless optical spectra. Nine of these lie within the range of colors of known x ray selected BL Lacs. Of the remaining four, one is apparently x ray louder (by a factor of 1.5) or optically quieter (by 0.8 mags); and three are optically louder (by 1-1.3 mags) than x ray selected BL Lacs. Approximately 50 new BL Lacs in total are expected from VLA work and upcoming Australia Telescope observations, yielding a complete Slew Survey sample of approximately 90 BL Lacs

Obscuration in the Host Galaxies of Soft X-ray Selected Seyferts

We define a new sample of 96 low-redshift (z<0.1), soft X-ray selected Seyferts from the catalog of the Einstein Slew Survey (Elvis etal. 1992, Plummer et al. 1994). We probe the geometry and column depth of obscuring material in the host-galaxy disks using galaxian axial ratios determined mainly from the Digitized Sky Survey. The distribution of host-galaxy axial ratios clearly shows a bias against edge-on spirals, confirming the existence of a geometrically thick layer of obscuring material in the host-galaxy planes. Soft X-ray selection recovers some of the edge-on objects missed in UV and visible surveys but still results in 30% incompleteness for Type 1's. We speculate that thick rings of obscuring material like the ones we infer for these Seyferts might be commonly present in early type spirals, sitting at the Inner Lindblad Resonances of the nonaxisymmetric potentials of the host galaxies.Comment: 14 pages including 2 tables and 3 eps figures, aas2pp4.sty, to appear in Ap

Early childhood educators’ knowledge, beliefs, education, experiences, and children’s language- and literacy-learning opportunities: What is the connection?

In this study, we investigated how multiple types of knowledge and beliefs, along with holding an early childhood-related degree and teaching experience, were linked to amounts of early childhood educators’ language and literacy instruction. Quantile regression was used to estimate associations between these variables along a continuum of language and literacy instruction for 222 early childhood educators. In general, low levels of language- and literacy-related instruction were observed; however, the use of quantile regression afforded unique insight into the associations of knowledge, beliefs, education, and teaching experience with instruction when levels of instruction were sufficient. These findings would not have been visible with traditional, linear regression models. Specifically, two types of knowledge were examined: disciplinary-related content knowledge about the structure of language and knowledge for use in teaching language and literacy to young children. Only educators’ disciplinary content knowledge was associated with amount of instruction. Associations between beliefs about language and literacy instruction and amount of instruction were less consistent. Generally, holding an early childhood related degree was positively associated with language and literacy instruction whereas teaching experience was negatively associated with the amount of instruction. Implications for studying educators and understanding the associations among educator characteristics and instruction are discussed