519 research outputs found
The growth cones of Aplysia sensory neurons: Modulation by serotonin of action potential duration and single potassium channel currents
Neuron-specific membrane glycoproteins promoting neurite fasciculation in Aplysia californica.
A Complete Version of the Glauber Theory for Elementary Atom - Target Atom Scattering and Its Approximations
A general formalism of the Glauber theory for elementary atom (EA) - target
atom (TA) scattering is developed. A second-order approximation of its complete
version is considered in the framework of the optical-model perturbative
approach. A `potential' approximation of a second-order optical model is
formulated neglecting the excitation effects of the TA. Its accuracy is
evaluated within the second-order approximation for the complete version of the
Glauber EA-TA scattering theory.Comment: PDFLaTeX, 10 pages, no figures; an updated versio
Designing surgical clothing and drapes according to the new technical standards
Hospitals will continue to be the largest consumers of disposables, because of the diverse range of procedures they provide. Favourable growth is forecast for nonwovens. Increasing concern over contamination and nosocomial infections will boost the demand for consumables and disposables surgical gowns and drapes. But, until now neither the manufacturers nor the end users of surgical gowns and drapes could agree on standards.
So, a mandatory European standard is being developed to establish basic requirements and test methods for disposable and reusable materials used for surgical gowns and drapes. Once this standard has been adopted, the continued use of cotton textiles and conventional cotton-polyester mixed textiles will become questionable.(undefined
Self-Assembly of Core-Shell Hybrid Nanoparticles by Directional Crystallization of Grafted Polymers
Nanoparticle self-assembly is an efficient bottom-up strategy for the
creation of nanostructures. In the standard approach, ligands are grafted on
the surfaces of nanoparticles to keep them separated and control interparticle
interactions. Ligands then remain secondary and usually are not expected to
order significantly during superstructure formation. Here, we investigate how
ligands can play a more primary role in the formation of inorganic-organic
hybrid materials. We graft poly(2-iso-propyl-2-oxazoline) (PiPrOx) as a
crystallizable shell onto SiO nanoparticles. By varying the PiPrOx grafting
density, solution stability, and nanoparticle aggregation behavior can be
controlled. Upon prolonged heating, anisotropic nanostructures form in
conjunction with the crystallization of the ligands. Self-assembly of hybrid
PiPrOx@SiO (shell@core) nanoparticles proceeds in two steps: First, rapid
formation of amorphous aggregates via gelation, mediated by the interaction
between nanoparticles through grafted polymers; second, slow radial growth of
fibers via directional crystallization, governed by the incorporation of
crystalline ribbons formed from unbound polymers coupling to the grafted
polymer shell. Our work reveals how crystallization-driven self-assembly of
ligands can create intricate hybrid nanostructures.Comment: 12 pages, 5 figure
Antimatter and Matter Production in Heavy Ion Collisions at CERN (The NEWMASS Experiment NA52)
Besides the dedicated search for strangelets NA52 measures light
(anti)particle and (anti)nuclei production over a wide range of rapidity.
Compared to previous runs the statistics has been increased in the 1998 run by
more than one order of magnitude for negatively charged objects at different
spectrometer rigidities. Together with previous data taking at a rigidity of
-20 GeV/c we obtained 10^6 antiprotons 10^3 antideuterons and two antihelium3
without centrality requirements. We measured nuclei and antinuclei
(p,d,antiprotons, antideuterons) near midrapidity covering an impact parameter
range of b=2-12 fm. Our results strongly indicate that nuclei and antinuclei
are mainly produced via the coalescence mechanism. However the centrality
dependence of the antibaryon to baryon ratios show that antibaryons are
diminished due to annihilation and breakup reactions in the hadron dense
environment. The volume of the particle source extracted from coalescence
models agrees with results from pion interferometry for an expanding source.
The chemical and thermal freeze-out of nuclei and antinuclei appear to coincide
with each other and with the thermal freeze-out of hadrons.Comment: 12 pages, 8 figures, to appear in the proceedings of the conference
on 'Fundamental Issues in Elementary Matter' Bad Honnef, Germany, Sept.
25-29, 200
Amphiphilic block copolymers featuring a reversible hetero Diels-Alder linkage
The present article reports the preparation of a novel class of switchable amphiphilic diblock copolymers with a temperature switchable linkage. Reversible addition fragmentation chain transfer (RAFT) polymerization was used to synthesize the individual blocks: for the preparation of the non-polar block{,} i.e. poly(isoprene-co-styrene) (P(I-co-S)) (9200 g mol-1 [less-than-or-equal] Mn [less-than-or-equal] 50 000 g mol-1{,} 1.22 [less-than-or-equal] D [less-than-or-equal] 1.36){,} a chain transfer agent (CTA{,} 3-((2-bromo-2-methylpropanoyl)oxy)propyl 2-(((dodecylthio)carbonothioyl)thio)-2-methylpropanoate) carrying a bromine group was employed{,} ready for subsequent cyclopentadienyl (Cp) transformation. For the preparation of the polar block{,} triethylene glycol methyl ether acrylate (TEGA) was polymerized (6600 g mol-1 [less-than-or-equal] Mn [less-than-or-equal] 35 000 g mol-1{,} 1.12 [less-than-or-equal] D [less-than-or-equal] 1.30) using a RAFT agent carrying a phosphoryl Z-group{,} which is able to undergo hetero Diels-Alder (HDA) ligation with Cp moieties. Both building blocks were conjugated at ambient temperature in the presence of ZnCl2 as catalyst yielding the amphiphilic block copolymer P(I-co-S)-b-PTEGA (16 000 g mol-1 [less-than-or-equal] Mn [less-than-or-equal] 68 000 g mol-1{,} 1.15 [less-than-or-equal] D [less-than-or-equal] 1.32). To investigate the bonding/debonding capability of the HDA linkage{,} high temperature nuclear magnetic resonance (HT-NMR) spectroscopy{,} high temperature dynamic light scattering (HT-DLS) and high temperature size exclusion chromatography (HT-SEC) were carried out{,} evidencing that efficiently switchable amphiphilic block copolymers were generated (>4 cycles)
First atom lifetime and scattering length measurements
The results of a search for hydrogen-like atoms consisting of
mesons are presented. Evidence for atom production
by 24 GeV/c protons from CERN PS interacting with a nickel target has been seen
in terms of characteristic pairs from their breakup in the same target
() and from Coulomb final state interaction (). Using
these results the analysis yields a first value for the atom lifetime
of fs and a first model-independent measurement of
the S-wave isospin-odd scattering length
( for isospin ).Comment: 14 pages, 8 figure
Bevacizumab continuation versus no continuation after first-line chemotherapy plus bevacizumab in patients with metastatic colorectal cancer: a randomized phase III non-inferiority trial (SAKK 41/06)
In this trial, stopping bevacizumab after completion of induction chemotherapy was associated with a shorter time to progression, but no statistically significant difference in overall survival compared with the bevacizumab continuation strategy. Non-inferiority could not be demonstrated. Treatment costs are substantially higher for continuous bevacizumab treatmen
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