153 research outputs found

    Leveraging the Power of Peer Groups for Refugee Integration

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    Refugee integration, one long-term solution to the large number of people fleeing their home countries, constitutes a challenge for both refugees and host societies. ICT and especially online peer groups seem promising to support this process. Building on literature demonstrating the societal benefits of peer groups, this paper proposes a novel peer-group-based approach to address refugee integration and introduces both an online and offline realization. A randomized field experiment in cooperation with public (refugee) services and a non-governmental organization makes it possible to expand existing research by quantitatively demonstrating societal benefits of online peer groups and ICT for refugee integration. Further, this paper is the first to assess the effectiveness of online and offline peer groups in one experimental setup comparatively. Results show that peer groups provide substantial value with respect to the integration domains social bridges, social bonds, rights and citizenship as well as safety and stability. While the outcome of the various integration domains differs for online and offline peer groups, participants’ adoption rates were higher for online peer groups

    Determination of Bulk Magnetic Volume Properties by Neutron Dark-Field Imaging

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    For the production of high-class electrical steel grades a deeper understanding of the magnetic domain interaction with induced mechanical stresses is strongly required. This holds for non-oriented (NO) as well as grain-oriented (GO) steels. In the case of non-oriented steels the magnetic property degeneration after punching or laser cutting is essential for selecting correct obstructing material grades and designing efficient electrical machines. Until now these effects stay undiscovered due to the lack of adequate investigation methods that reveal local bulk information on processed laminations. Here we show how the use of a non-destructive testing method based on a neutron grating interferometry providing the dark-field image contrast delivers spatially-resolved transmission information about the local bulk domain arrangement and domain wall density. With the help of this technique it is possible to visualize magnetization processes within the NO laminations. Different representative manufacturing techniques are compared in terms of magnetic flux density deterioration such as punching, mechanically cutting by guillotine as well as laser fusion cutting using industrial high power laser beam sources. For GO steel laminations the method is applicable on the one hand to visualize the internal domain structure without being hindered by the coating layer. On the other hand, we can show the influence of the coating layer onto the underlying domain structure

    Forschungsprojekte mit der Praxis entwickeln: Ergebnisse des Projektentwicklungsprozesses der Innovationsgruppe ginkoo

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    Organic farming actors need to handle more complex innovation processes to develop locally adapted and globally relevant solutions for challenges such as agricultural-biodiversity and relationship between farmers and producers. For a coordinating management of such innovation processes, management tools that exceed classical innovation management techniques, are required if sustainable solutions are to be achieved. Developing relevant knowledge requires a transdisciplinary approach to bridge the gap between science and practice. This paper presents our process and the resulting concept of the transdisciplinary innovation group ginkoo for one of two case studies. It aims at developing a research concept that integrates the practical context such that ground for using the research findings after the end of funding has been laid

    The fine-scale structure of the trade wind cumuli over Barbados – An introduction to the CARRIBA project

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    The CARRIBA (Cloud, Aerosol, Radiation and tuRbulence in the trade wInd regime over BArbados) project, focused on high resolution and collocated measurements of thermodynamic, turbulent, microphysical, and radiative properties of trade wind cumuli over Barbados, is introduced. The project is based on two one-month field campaigns in November 2010 (climatic wet season) and April 2011 (climatic dry season). Observations are based on helicopter-borne and ground-based measurements in an area of 100 km2 off the coast of Barbados. CARRIBA is accompanied by long-term observations at the Barbados Cloud Observatory located at the East coast of Barbados since early in 2010 and which provides a longer-term context for the CARRIBA measurements. The deployed instrumentation and sampling strategy are presented together with a classification of the meteorological conditions. The two campaigns were influenced by different air masses advected from the Caribbean area, the Atlantic Ocean, and the African continent which led to distinct aerosol conditions. Pristine conditions with low aerosol particle number concentrations of ∌100 cm3 were alternating with periods influenced by Saharan dust or aerosol from biomass burning resulting in comparably high number concentrations of ∌ 500 cm3. The biomass burning aerosol was originating from both the Caribbean area and Africa. The shallow cumulus clouds responded to the different aerosol conditions with a wide range of mean droplet sizes and number concentrations. Two days with different aerosol and cloud microphysical properties but almost identical meteorological conditions have been analyzed in detail. The differences in the droplet number concentration and droplet sizes appear not to show any significant change for turbulent cloud mixing, but the relative roles of droplet inertia and sedimentation in initiating coalescence, as well as the cloud reflectivity, do change substantially. © Author(s) 2013

    Prostate-specific antigen testing in Tyrol, Austria: prostate cancer mortality reduction was supported by an update with mortality data up to 2008

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    Objectives: The objective of this study was to update an in-depth analysis of the time trend for prostate cancer (PCA) mortality in the population of Tyrol by 5 years, namely to 2008. In Tyrol, prostate-specific antigen (PSA) tests were introduced in 1988/89; more than three-quarters of all men in the age group 45–74 had at least one PSA test in the past decade. Methods: We applied the same model as in a previous publication, i.e., an age-period-cohort model using Poisson regression, to the mortality data covering more than three decades from 1970 to 2008. Results: For Tyrol from 2004 to 2008 in the age group 60+ period terms show a significant reduction in prostate cancer mortality with a risk ratio of 0.70 (95% confidence interval 0.57, 0.87) for Tyrol, and for Austria excluding Tyrol a moderate reduction with a risk ratio of 0.92 (95% confidence interval 0.87, 0.97), each compared to the mortality rate in the period 1989–1993. Conclusions: This update strengthens our previously published results, namely that PSA testing offered to a population at no charge can reduce prostate cancer mortality. The extent of mortality reduction is in line with that reported in the other recent publications. However, our data do not permit us to fully assess the harms associated with PCA screening, and no recommendation for PSA screening can be made without a careful evaluation of overdiagnosis and overtreatment

    The fine-scale structure of the trade wind cumuli over Barbados – An introduction to the CARRIBA project

    Get PDF
    The CARRIBA (Cloud, Aerosol, Radiation and tuRbulence in the trade wInd regime over BArbados) project, focused on high resolution and collocated measurements of thermodynamic, turbulent, microphysical, and radiative properties of trade wind cumuli over Barbados, is introduced. The project is based on two one-month field campaigns in November 2010 (climatic wet season) and April 2011 (climatic dry season). Observations are based on helicopter-borne and ground-based measurements in an area of 100 km2 off the coast of Barbados. CARRIBA is accompanied by long-term observations at the Barbados Cloud Observatory located at the East coast of Barbados since early in 2010 and which provides a longer-term context for the CARRIBA measurements. The deployed instrumentation and sampling strategy are presented together with a classification of the meteorological conditions. The two campaigns were influenced by different air masses advected from the Caribbean area, the Atlantic Ocean, and the African continent which led to distinct aerosol conditions. Pristine conditions with low aerosol particle number concentrations of ∌100 cm3 were alternating with periods influenced by Saharan dust or aerosol from biomass burning resulting in comparably high number concentrations of ∌ 500 cm3. The biomass burning aerosol was originating from both the Caribbean area and Africa. The shallow cumulus clouds responded to the different aerosol conditions with a wide range of mean droplet sizes and number concentrations. Two days with different aerosol and cloud microphysical properties but almost identical meteorological conditions have been analyzed in detail. The differences in the droplet number concentration and droplet sizes appear not to show any significant change for turbulent cloud mixing, but the relative roles of droplet inertia and sedimentation in initiating coalescence, as well as the cloud reflectivity, do change substantially

    Strangeness production in proton-proton and proton-nucleus collisions

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    In these lectures we discuss the investigation of the strange meson production in proton-proton (pppp) and in proton-nucleus (pApA) reactions within an effective Lagrangian model. The kaon production proceeds mainly via the excitations of N∗N^*(1650), N∗N^*(1710), and N∗N^*(1720) resonant intermediate nucleonic states, in the collision of two initial state nucleons. Therefore, the strangeness production is expected to provide information about the resonances lying at higher excitation energies. For beam energies very close to the kaon production threshold the hyperon-proton final state interaction effects are quite important. Thus, these studies provide a check on the models of hyperon-nucleon interactions. The in-medium production of kaons show strong sensitivity to the self energies of the intermediate mesons.Comment: 16 pages, 9 figures, Talk presented in the workshop on Hadron Physics, Puri, India, March 7-17,200

    B cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B cell lymphoma in mice

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    The adaptor protein MYD88 is critical to relay activation of Toll-like receptor signaling to NF-{kappa}B activation.MYD88 mutations, particularly the p.L265P mutation, have been described in numerous distinct B cell malignancies, including diffuse large B cell lymphoma (DLBCL). 29% of activated B cell (ABC)-type DLBCL, which is characterized by constitutive activation of the NF-{kappa}B pathway, carry the p.L265P mutation. In addition, ABC-DLBCL frequently displays focal copy number gains affecting BCL2. Here, we generated a novel mouse model, in which Cre-mediated recombination, specifically in B cells, leads to the conditional expression of Myd88(p.L252P)(the orthologous position of the human MYD88(p.L265P) mutation) from the endogenous locus. These animals develop a lympho-proliferative disease, and occasional transformation into clonal lymphomas. The clonal disease displays morphological and immunophenotypical characteristics of ABC-DLBCL. Lymphomagenesis can be accelerated by crossing in a further novel allele, which mediates conditional overexpression ofBCL2 Cross-validation experiments in human DLBCL samples revealed that bothMYD88andCD79Bmutations are substantially enriched in ABC-DLBCL, compared to germinal center B cell DLBCL. Furthermore, analyses of human DLBCL genome sequencing data confirmed that BCL2 amplifications frequently co-occur with MYD88 mutations, further validating our approach. Lastly,in silicoexperiments revealed that particularly MYD88-mutant ABC-DLBCL cells display an actionable addiction to BCL2. Altogether, we generated a novel autochthonous mouse model of ABC-DLBCL, which could be used as a preclinical platform for the development and validation of novel therapeutic approaches for the treatment of ABC-DLBCL

    Role of N*(1650) in the near threshold pp --> p Lambda K+ and pp --> p Sigma0 K+ reactions

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    We investigate the pp --> p Lambda K+ and pp --> p Sigma0 K+ reactions at beam energies near their thresholds within an effective Lagrangian model, where the strangeness production proceeds via the excitation of N*(1650), N*(1710), and N*(1720) baryonic resonances. It is found that the N∗N^*(1650) resonance dominates both these reactions at near threshold energies. The contributions from this resonance together with the final state interaction among the outgoing particles are able to explain the observed beam energy dependence of the ratio of the cross sections of the two reactions in the near threshold region.Comment: Revised version, Fig. 4 is updated with the revised data, to appear in Phys. Rev. C (Rapid Communications
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