45 research outputs found

    Progressive regression of left ventricular hypertrophy two years after bariatric surgery.

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    BACKGROUND: Obesity is a systemic disorder associated with an increase in left ventricular mass and premature death and disability from cardiovascular disease. Although bariatric surgery reverses many of the hormonal and hemodynamic derangements, the long-term collective effects on body composition and left ventricular mass have not been considered before. We hypothesized that the decrease in fat mass and lean mass after weight loss surgery is associated with a decrease in left ventricular mass. METHODS: Fifteen severely obese women (mean body mass index [BMI]: 46.7+/-1.7 kg/m(2)) with medically controlled hypertension underwent bariatric surgery. Left ventricular mass and plasma markers of systemic metabolism, together with body mass index (BMI), waist and hip circumferences, body composition (fat mass and lean mass), and resting energy expenditure were measured at 0, 3, 9, 12, and 24 months. RESULTS: Left ventricular mass continued to decrease linearly over the entire period of observation, while rates of weight loss, loss of lean mass, loss of fat mass, and resting energy expenditure all plateaued at 9 [corrected] months (P \u3c.001 for all). Parameters of systemic metabolism normalized by 9 months, and showed no further change at 24 months after surgery. CONCLUSIONS: Even though parameters of obesity, including BMI and body composition, plateau, the benefits of bariatric surgery on systemic metabolism and left ventricular mass are sustained. We propose that the progressive decrease of left ventricular mass after weight loss surgery is regulated by neurohumoral factors, and may contribute to improved long-term survival

    Caracol, Belize, and Changing Perceptions of Ancient Maya Society

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    Expanding opportunities for online shoppers with disabilities

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    The Internet promises many opportunities for consumers who shop online. While prior studies identify problems with online access for persons with disabilities, research has not examined whether consumers with disabilities shop online similarly to persons who are not disabled. The study attempts to fill this gap in two unique ways. First, this paper specifically considers the frequency of online shopping, the amount spent, and reasons for shopping online among both disabled and non-disabled persons. In addition, the study groups persons with disabilities into six major categories according to disability type rather than aggregating into one general category. Telephone surveys of 1053 persons reveal both differences and similarities that suggest opportunities for improving online access and developing a richer understanding of the online shopping motivations and needs of persons with disabilities.Internet Online retailing Disability

    Getting Fit, Staying Fit: Developing Lean and Responsive Organisations

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