16 research outputs found
Developing physical activity interventions for children with a visual impairment:lessons from the First Steps initiative
Children with a visual impairment are less active than their sighted peers. Yet they are born with the potential to match their sighted peers’ motor skill competency and levels of physical fitness. Environmental barriers are one of the main causes of inequities. This paper provides insight on these issues, drawing upon a physical activity intervention called ‘First Steps’, a British Blind Sport initiative that aimed to get more children with a visual impairment more active.Physical activity packs were delivered to 53 children aged 5-15 years old with a visual impairment. Of these participants, 62% had additional impairments or medical conditions. A mixed-methods approach was used to gather participants’ experiences of physical activity prior to receiving this pack and canvas opinion on how the pack changed their activity levels. The findings revealed inequitable experiences of physical activity. The First Steps pack made considerable progress in developing children’s physical activity levels. Participants’ motor skills, social interactions and confidence improved. Organisations working with this population might look to adopt a similar concept. Recommendations for those wishing to do so are provided.<br/
Employability and graduate outcomes for sports students with widening participation characteristics – an analysis of a data derived from 2000-2015
The advent of the Teaching Excellence Framework has placed increased focus on graduate outcomes, widening participation and learning gain within the Higher Education sector. However, it is acknowledged that there is an ‘unequal playing field’ with regard to graduate employment with socio-economic background viewed as the primary determinant of the graduate’s future (UUK, 2016). The authors conducted a study tracking career trajectories for those students graduating from an Abertay sports degree programme in the time period 2000-2015. These programmes were originally only offered as advanced entry routes for students with further education awards enabling them to extend their qualifications and access graduate employment. The programmes have evolved over the study period and now offer a range of entry points. This presentation will consider employability outcomes for those completing studies from ‘first in family homes’, from lower socioeconomic households, and for those who enrolled with a further education qualification
An investigation into the comparative learning gain and ‘value added’ for students from widening participation and non-widening participation groups:a case study from sports degrees
Increasingly universities are expected to demonstrate the impact of students’ higher education experiences; learning gain is one of the metrics that can evidence this. The Scottish Funding Council (SFC) agrees Widening Participation (WP) objectives with the universities with an implicit expectation that Scottish higher education institutions (HEIs) work within their communities to enable those who could benefit from a university education to enrol. The Abertay sport programmes have historically supported students from diverse backgrounds. This case study focuses specifically on the graduate outcomes of WP and non-WP students graduating from these programmes in the years 2000–2015. An e-mail survey and departmental database of graduate destinations were linked with the student record. Analysis confirmed that those from WP backgrounds were equally as likely to gain a good degree as their non-WP counterparts and to be in graduate and/or sports employment. Longitudinal graduate outcomes are considered in the context of pedagogic strategy
Tracking career destinations of sports graduates 2000-2015:a longitudinal exploration of destinations and preparedness for the workplace
The advent of the TEF means that universities will be expected to evidence the impact of curriculum interactions on graduate destinations and social mobility. Over a third of sport employees are graduates but little data charts their career journeys. Key objectives: • track all Abertay sport graduates from the programmes’ inception • compare Honours and non-Honours graduates’ destination data • examine career trajectories • explore preparedness for the workplace • utilise demographic data to contextualise findings. 452 graduates were e-mailed.123 responded to the survey, 84% being in identifiable graduate level jobs. Across time, increasing proportions of students were Honours' graduates. Social class, gender and disability did not impact on this but articulation from FE was a significant factor (χ2 =84.68, p<0.01). Very few respondents (n=13) felt that their degree had not equipped them for working life. 'Placement' and 'research methods skills' were of most benefit in preparing for the workplace
The student journey:student as researcher and postgraduate skill development
This case study provides a reflective account of the experiences of a student researcher recruited to a project exploring the career journeys of sports graduates from 2000-2015. While a final year undergraduate sport student, the lead author was employed to collect and organise the output for a funded employability transitions project. This article considers the methodology and some of the output from the project, but more specifically focuses on personal skill development and the student’s preparedness for the transition to postgraduate study. The paper provides an overview of what motivated the student to become involved in the project and her early expectations of what being a research assistant would entail. It also charts the evolution of skills across the duration of the project and how these have transferred to her current status as a postgraduate research student. The personal account is contextualised to literature regarding the requirements of postgraduate study and work regarding students as partners, with the reader invited to consider opportunities in their own institutions for this type of development activity, with the aim being to ease transition to this level of study
Counselling trajectories:what happens after graduation?
A comprehensive report on the provision of training in Counselling and Psychotherapy (Hulme and Rutton, 2013) proposed that one of the main areas for future research is investigation in to what happens to counselling students following qualification. This study, carried out in 2016, investigated the career trajectories of Abertay counselling students and looked to evaluate their career pathway once qualified. Additionally, the study looked to explore the links between course content and employability with a view to ensuring that the programme is relevant and continues to meet industry needs. Some key findings will be presented within this poster
The Immune Landscape of Undifferentiated Pleomorphic Sarcoma
INTRODUCTION: Undifferentiated pleomorphic sarcoma (UPS) can be associated with a relatively dense immune infiltration. Immune checkpoint inhibitors (anti-PD1, anti-PDL1, and anti-CTLA4) are effective in 20% of UPS patients. We characterize the immune microenvironment of UPS and its association with oncologic outcomes.
MATERIAL AND METHODS: Surgically resected UPS samples were stained by immunohistochemistry (IHC) for the following: tumor-associated immune cells (CD3, CD8, CD163, CD20), immune checkpoints (stimulatory: OX40, ICOS; inhibitory: PD-L1, LAG3, IDO1, PD1), and the adenosine pathway (CD73, CD39). Sections were reviewed for the presence of lymphoid aggregates (LA). Clinical data were retrospectively obtained for all samples. The Wilcoxon rank-sum and Kruskal-Wallis tests were used to compare distributions. Correlations between biomarkers were measured by Spearman correlation. Univariate and multivariate Cox models were used to identify biomarkers associated with overall survival (OS) and disease-free survival (DFS). Unsupervised clustering was performed, and Kaplan-Meier curves and log-rank tests used for comparison of OS and DFS between immune clusters.
RESULTS: Samples analyzed (n=105) included 46 primary tumors, 34 local recurrences, and 25 metastases. LA were found in 23% (n=10/43), 17% (n=4/24), and 30% (n=7/23) of primary, recurrent, and metastatic samples, respectively. In primary UPS, CD73 expression was significantly higher after preoperative radiation therapy (p=0.009). CD39 expression was significantly correlated with PD1 expression (primary: p=0.002, recurrent: p=0.004, metastatic: p=0.001), PD-L1 expression (primary: p=0.009), and CD3+ cell densities (primary: p=0.016, recurrent: p=0.043, metastatic: p=0.028). In recurrent tumors, there was a strong correlation between CD39 and CD73 (p=0.015), and both were also correlated with CD163+ cell densities (CD39 p=0.013; CD73 p\u3c0.001). In multivariate analyses, higher densities of CD3+ and CD8+ cells (Cox Hazard Ratio [HR]=0.33; p=0.010) were independently associated with OS (CD3+, HR=0.19, p\u3c0.001; CD8+, HR= 0.33, p=0.010) and DFS (CD3+, HR=0.34, p=0.018; CD8+, HR=0.34, p= 0.014). Unsupervised clustering of IHC values revealed three immunologically distinct clusters: immune high, intermediate, and low. In primary tumors, these clusters were significantly associated with OS (log-rank p\u3c0.0001) and DFS (p\u3c0.001).
CONCLUSION: We identified three immunologically distinct clusters of UPS Associated with OS and DFS. Our data support further investigations of combination anti-PD-1/PD-L1 and adenosine pathway inhibitors in UPS