586 research outputs found

    Understanding policy volatility in Sudan:

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    "In this paper we present the findings of a qualitative investigation into some dimensions and implications of policy volatility in the realms of natural resource (NR) governance and devolution in contemporary Sudan, with particular reference to Greater Kordofan. Our goal is to map out some aspects of the interplay between volatility, disempowerment processes affecting both state agents and the rural population, and certain problems of governance that are characteristic but not unique to Sudan. In particular, we argue that volatility is a dimension of poor governance worthy of investigation in its own right, as it is a primary ingredient of what we may call a “self-disempowering state,” where adaptive learning in policy processes is impeded and successful devolution faces particularly complex obstacles. The policy domain that we consider for analysis includes laws, regulations and policies enacted under the label of “Decentralization, Land Allocation and Land Use,” as well as large development projects supporting the decentralization or devolution of NR management to local communities in the region." from Authors' AbstractPolicy Volatility, Devolution, Communities, Governance, Rural population., Decentralization, Natural resource management, Land allocation, Land use, Greater Kordofan,

    Prevalence and Risk Factors of Obesity among Elderly attending Geriatric Outpatient Clinics in Mansoura City

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    Obesity is a major public health problem affecting all ages in both developed and developing countries. It is considered the fifth leading risk factor for deaths all over the world as about 2.8 million people die due to obesity each year directly or indirectly.  Obesity in elderly is considered one of the most serious public health challenges for all over the world. It is a complex; multifactorial disease arises from the interactions between genetic, environmental and behavioral factors together with other factors results in energy imbalance and promotes excessive fat deposition. Aim: to Determine Prevalence and Risk Factors of Obesity among Elderly attending Geriatric Outpatient Clinics in Mansoura City. Method: Descriptive, analytical, cross sectional hospital based research design was used. The study carried out on 126 elderly attending Geriatric outpatient clinics in the specialized medical hospital and general hospital in Mansoura City. Data was collected using 3 tools, socio-demographic and clinical data structured interview sheet, Health promoting Lifestyle profile II (HPLPII), Body Mass Index. Results: The results indicate that the prevalence of obesity among elderly attending Geriatric Outpatient Clinics in Mansoura City was 33.3% and there was significant relation between positive family history of obesity, unhealthy lifestyle as poor nutritional habits, and lack of physical activity, poor stress management and obesity. Conclusion: Increase awareness about obesity and healthy lifestyle is essential for elderly to prevent obesity and its complications. Keywords: Obesity, Elderly, Risk Factors, prevalence, Lifestyl

    Molecular epidemiology of antibiotic-associated diarrhoea due to Clostridium difficile and clostridium perfringens in Ain Shams University Hospitals

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    Background: As we are living in the era of antibiotic overuse, antibiotic associated diarrhea (AAD) is considered now a distinct health problem with a need for more attention. Aim of the Study: was to perform a highly specific detection and definition of pathogenic Clostridium perfringens and Clostridium difficile related AAD in children compared to adults and geriatircs. Patients and Methods: One hundred and fifty patients diagnosed for AAD were included in this study (50 children, 50 adults and 50 geriatric patients). All of them were subjected to full medical history including complete therapeutic history of antibiotics and collection of stool sample during the attack for detection of Clostridium perfringenes enterotoxin (CPEnt) and Clostridium difficile cytotoxin by (EIA) kit. PCR detection of Clostridium perfringenes cpe gene (Coding gene for CPEnt) was performed as well. Results: Results showed that prevalence of Clostridium difficile cytotoxin was 24% while Clostridium perfringenes enterotoxin was 12% as detected by EIA in faecal specimens as a whole. Detection of cpe gene by PCR was positive in 16% of all cases. Children (OR: 4.2, 95% CI: 1.3-14.8, P_0.01) and geriatric patients (OR: 3.4, 95% CI: 1.2-13.5, P_0.02) were significantly more prone to Clostridium difficile AAD compared to adults. Also, childhood was a significant risk for Clostridium perfringens AAD (OR: 2.1, 95% CI: 0.54-7.4, P_0.04). In Conclusion: children and geriatric patients are more vulnerable to develop AAD with antibiotic abuse compared to adults. Abbreviations: AAD=Antibiotic associated diarrhea, CI=Confidence interval, ELISA=Enzyme-linked immunosorbent assay, OR=Odd ratio, PCR=Polymerase chain reaction. Keywords: Antibiotic-associated diarrhea, children, Clostridium perfringens, Clostridium difficile. Egypt. J. Hum. Genet Vol. 8 (2) 2007: pp. 121-13

    Descriptive Epidemiology of Hemophilia and Other Coagulation Disorders in Mansoura, Egypt: Retrospective Analysis.

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    Hemophilia represent the most severe inherited bleeding disorder (INB), it’s thought to affect inviduals from all geographical areas in equal frequency. In Egypt which has a population of approximately (80million) consanguineous marriage are frequent, therefore autosomal recessive coagulation disorders reach a higher prevalence than in many other countries

    Effect of subchronic intake of green tea extract on liver of albino rat histomorphometric, ultrastructural and biochemical study

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    Background: There are conflicting reports on the effect of green tea extract (GTE) on the liver of animals. Some studies failed to show any adverse hepatic effects following administration of GTE to mice, rats, and dogs. Others reported severe hepatic necrosis, resulting in death in female Swiss-Webster mice following its administration. The aim of the study was to examine the subchronic toxicity of GTE on the liver of the adult male albino rats. Materials and methods: Forty male adult Wistar albino rats were used in the study. The rats were divided into four groups; group I (control), group II (low-dose green tea), group III (medium-dose green tea) and group IV (high-dose green tea). Histological, biochemical and histomorphometric analyses were done. Results: Mild hepatic affections were observed in group II. The affections were severe in groups III and IV. The central veins and hepatic sinusoids were congested. The hepatocytes were degenerated. Hypertrophy of the hepatic arteries, dilation of the bile ducts and cellular infiltration were clearly observed in the last two groups. Mild degenerative changes were observed in the hepatocytes in rat’s group II; the cytoplasm was rarefied and vacuolated. Some mitochondria were ruptured. The blood sinusoids were congested. The rough endoplasmic retinaculum was fragmented in group III. More degenerative changes were observed in group IV; the hepatic architectures were lost with disruption of cell membranes. Most of the cell organelles were degenerated and most of mitochondria were ballooned. As compared to that of the control groups: the total serum protein values in groups II, III and IV showed a statistically significant decrease (12%, 20% and 21%, respectively), the mean area per cent of collagen fibres in groups III and IV increased 5 and 7 folds. Conclusions: Subchronic administration of GTE resulted in structural and functional affection of the rats’ liver. The dose of 250 mg/kg/day seemed to be safe, while the doses of 500 mg/kg/day and 1000 mg/kg/day had deleterious effect being more evident in the latter dose

    Role of serum allograft inflammatory factor-1 (AIF-1) in Egyptian type 2 diabetic patients

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    Background. Diabetes mellitus (DM) is a powerful and independent risk factor for cardiovascular disease. The atherosclerosis process in diabetes is indistinguishable from that of the nondiabetic population, but it begins earlier and is often more extensive and more severe. AIF-1 promotes chemotaxis, spreading and migration of macrophages and vascular smooth muscle cells (VSMCs) which suggest a role of AIF-1 in the atherosclerotic plaque formation. Thus, this study determines the role of AIF-1 in the Egyptian type 2 diabetic patients. Results. The level of AIF-1 was significantly higher in the type 2 diabetic group when compared to the control group (p = 0.000). In type 2 diabetic patients group, there was a significant positive correlation between CIMT and AIF-1 (r = 0.468, p = 0.000). In addition to the positive correlation between CIMT and AIF-1, CIMT in regression model analysis was significantly positive contributing to the outcome variable (AIF-1) (p < 0.05), denoting the possible role of elevated serum AIF-1 level in atherosclerotic process with further studies on larger scale needed

    Effect of FSW Parameters on The Microstructure and Mechanical Properties of T-joints between Dissimilar Al-Alloys

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    The main purpose of this research is to develop T-joints between the aluminum AA 2024-T4 and AA 7075-T6 using friction stir welding.  The effect of tool geometries, tool traveling speed, and rotational rate in the welded T-joints were investigated and discussed. Three different tools were used with different shoulder to pin ratios 3.28, 3.36, and 4.31. After optimization, the best tool dimension has used with the different rotational and welding speeds. Three tool traverse speeds of 50, 75, and 100 mm/min were used. Two rotation rates of 800 rpm and 1000 rpm were applied. After FSW, at a number of the above FSW parameters' combinations, macrostructure and microstructure analyses were done using optical microscopy. In order to have an insight into the mechanical properties, hardness measurements and tensile testing were carried out. Using small shoulder to pin ratio produced visually unacceptable T-joint. Opposite happened by using the tool with 4.31 of shoulder to pin ratio. Furthermore, the results showed sound T-welds with no obvious defects at high rotational rate of 1000 rpm with the two used traveling speeds. Asymmetric temperature distribution was observed between the two sides, advance side (AS) and retreating side (RS

    Optimization of CNFET Parameters for High Performance Digital Circuits

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    The Carbon Nanotube Field Effect Transistor (CNFET) is one of the most promising candidates to become successor of silicon CMOS in the near future because of its better electrostatics and higher mobility. The CNFET has many parameters such as operating voltage, number of tubes, pitch, nanotube diameter, dielectric constant, and contact materials which determine the digital circuit performance. This paper presents a study that investigates the effect of different CNFET parameters on performance and proposes a new CNFET design methodology to optimize performance characteristics such as current driving capability, delay, power consumption, and area for digital circuits. We investigate and conceptually explain the performance measures at 32 nm technologies for pure-CNFET, hybrid MOS-CNFET, and CMOS configurations. In our proposed design methodology, the power delay product (PDP) of the optimized CNFET is about 68%, 63%, and 79% less than that of the nonoptimized CNFET, hybrid MOS-CNFET, and CMOS circuits, respectively. Therefore, the proposed CNFET design is a strong candidate to implement high performance digital circuits
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