Чинники ефективності антикризового управління суб'єктами господарювання в економіці України

У статті розглядаються проблеми формування підходів організації антикризового управління суб'єктами господарювання в економіці України. На ґрунті вітчизняного та зарубіжного досвіду й результатів власних досліджень автора запропоновано психологічний тип антикризового менеджера. (The article is devoted to the problems of forming of approaches of organization of anticrisis management by the subjects of menage in the economy of Ukraine. On the base of domestic and foreign experience and results of own researches of author the psychological type of anticrisis manager is offered.

Aggregation-Induced Fabrication of Fluorescent Organic Nanorings: Selective Biosensing of Cysteine and Application to Molecular Logic Gate

Self-aggregation behavior in aqueous medium of four naphthalimide derivatives has exhibited substitution-dependent, unusual, aggregation induced emission enhancement (AIEE) phenomena. Absorption, emission, and time-resolved study initially indicated the formation of J-type fluorescent organic nanoaggregates (FONs). Simultaneous applications of infrared spectroscopy, theoretical studies, and dynamic light scattering (DLS) measurements explored the underlying mechanism of such substitution-selective aggregation of a chloro-naphthalimide organic molecule. Furthermore, transmission electron microscopy (TEM) visually confirmed the formation of ring like FONs with average size of 7.5–9.5 nm. Additionally, naphthalimide FONs also exhibited selective and specific cysteine amino acid sensing property. The specific behavior of NPCl aggregation toward amino acids was also employed as a molecular logic gate in information technology (IT)

Soft-Templated Room Temperature Fabrication of Nanoscale Lanthanum Phosphate: Synthesis, Photoluminescence, and Energy-Transfer Behavior

We herein report a simple and effective soft template mediated synthesis protocol for the room temperature preparation of highly crystalline cerium (Ce³⁺) and terbium (Tb³⁺) doped lanthanum phosphate (LaPO₄) nanorods (NRs) and nanoflowers. Anionic surfactant sodium bis­(2-ethylhexyl) sulfosuccinate (AOT)/<i>n</i>-alkane soft template was chosen since it forms stable reverse micelles (RMs). Transmission electron microscopy (TEM) analysis corroborated successful formation of LaPO₄:Ce³⁺,Tb³⁺ NRs having different aspect ratios (ranging from 2.8:1 to 7.6:1) under varying reaction conditions. The crystalline nature of the nanomaterials (NMs) was ascertained by X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), and small-area electron diffraction (SAED) studies. Energy-dispersive X-ray (EDX) and Fourier transform infrared (FTIR) spectroscopy further verified the elemental existence of the desirably synthesized nanostructures. Experimental results from thermogravimetric-differential thermal analysis (TG-DTA) revealed thermal stability of the NRs up to 800 °C. The prepared NRs exhibit strong yellowish-green photoluminescence (PL) at 544 nm (⁵D₄ → ⁷F₅) when excited at 270 nm. Furthermore, time-resolved decay analysis along with steady-state PL measurements indicated an efficient energy transfer (ET) phenomenon between Ce³⁺ and Tb³⁺ ions doped in LaPO₄ (LAP) host matrix

Understanding the Effect of Single Cysteine Mutations on Gold Nanoclusters as Studied by Spectroscopy and Density Functional Theory Modeling

Fluorescent metal nanoclusters have generated considerable excitement in nanobiotechnology, particularly in the applications of biolabeling, targeted delivery, and biological sensing. The present work is an experimental and computational study that aims to understand the effects of protein environment on the synthesis and electronic properties of gold nanoclusters. MPT63, a drug target of <i>Mycobacterium tuberculosis</i>, was used as the template protein to synthesize, for the first time, gold nanoclusters at a low micromolar concentration of the protein. Two single cysteine mutants of MPT63, namely, MPT63Gly20Cys (mutant I) and MPT63Gly40Cys (mutant II) were employed for this study. The experimental results show that cysteine residues positioned in two different regions of the protein induce varying electronic states of the nanoclusters depending on the surrounding amino acids. A mixture of five-atom and eight-atom clusters was generated for each mutant, and the former was found to be predominant in both cases. Computational studies, including density functional theory (DFT), frontier molecular orbital (FMO), and natural bond orbital (NBO) calculations, validated the experimental observations. The as-prepared protein-stabilized nanoclusters were found to have applications in the imaging of live cells