Possible Constraints on the Time Variation of the Fine Structure Constant from Cosmic Microwave Background Data

The formation of the cosmic microwave background radiation (CMBR) provides a very powerful probe of the early universe at the epoch of recombination. Specifically, it is possible to constrain the variation of fundamental physical constants in the early universe. We have calculated the effect of a varying electromagnetic coupling constant (\alpha) on the CMBR and find that new satellite experiments should provide a tight constraint on the value of \alpha at recombination which is complementary to existing constraints. An estimate of the obtainable precision is |\dot{\alpha}/\alpha| \leq 7 x 10^{-13} y^{-1} in a realistic experiment.Comment: 5 pages, 3 postscript figures, matches version to appear in Phys. Rev.

Constraining fundamental constants of physics with quasar absorption line systems

We summarize the attempts by our group and others to derive constraints on variations of fundamental constants over cosmic time using quasar absorption lines. Most upper limits reside in the range 0.5-1.5x10-5 at the 3sigma level over a redshift range of approximately 0.5-2.5 for the fine-structure constant, alpha, the proton-to-electron mass ratio, mu, and a combination of the proton gyromagnetic factor and the two previous constants, gp(alpha^2/mu)^nu, for only one claimed variation of alpha. It is therefore very important to perform new measurements to improve the sensitivity of the numerous methods to at least <0.1x10-5 which should be possible in the next few years. Future instrumentations on ELTs in the optical and/or ALMA, EVLA and SKA pathfinders in the radio will undoutedly boost this field by allowing to reach much better signal-to-noise ratios at higher spectral resolution and to perform measurements on molecules in the ISM of high redshift galaxies.Comment: 11 pages, 3 figure

Search for varying constants of nature from astronomical observation of molecules

The status of searches for possible variation in the constants of nature from astronomical observation of molecules is reviewed, focusing on the dimensionless constant representing the proton-electron mass ratio $\mu=m_p/m_e$. The optical detection of H$_2$ and CO molecules with large ground-based telescopes (as the ESO-VLT and the Keck telescopes), as well as the detection of H$_2$ with the Cosmic Origins Spectrograph aboard the Hubble Space Telescope is discussed in the context of varying constants, and in connection to different theoretical scenarios. Radio astronomy provides an alternative search strategy bearing the advantage that molecules as NH$_3$ (ammonia) and CH$_3$OH (methanol) can be used, which are much more sensitive to a varying $\mu$ than diatomic molecules. Current constraints are $|\Delta\mu/\mu| < 5 \times 10^{-6}$ for redshift $z=2.0-4.2$, corresponding to look-back times of 10-12.5 Gyrs, and $|\Delta\mu/\mu| < 1.5 \times 10^{-7}$ for $z=0.88$, corresponding to half the age of the Universe (both at 3$\sigma$ statistical significance). Existing bottlenecks and prospects for future improvement with novel instrumentation are discussed.Comment: Contribution to Workshop "High Performance Clocks in Space" at the International Space Science Institute, Bern 201

X-Ray Synchrotron Emission from 10-100 TeV Cosmic-Ray Electrons in the Supernova Remnant SN 1006

We present the results of a joint spectral analysis of RXTE PCA, ASCA SIS, and ROSAT PSPC data of the supernova remnant SN 1006. This work represents the first attempt to model both the thermal and nonthermal X-ray emission over the entire X-ray energy band from 0.12 to 17 keV. The thermal flux is described by a nonequilibrium ionization model with an electron temperature kT = 0.6 keV, an ionization timescale n0t = 9 x 10^9 s / cm^3, and a relative elemental abundance of silicon that is 10-18 times larger than the solar abundance. The nonthermal X-ray spectrum is described by a broken power law model with low- and high-energy photon indices Gamma_1 = 2.1 and Gamma_2 = 3.0, respectively. Since the nonthermal X-ray spectrum steepens with increasing energy, the results of the present analysis corroborate previous claims that the nonthermal X-ray emission is produced by synchrotron radiation. We argue that the magnetic field strength is significantly larger than previous estimates of about 1 x 10^-5 G and arbitrarily use a value of 4 x 10^-5 G to estimate the parameters of the cosmic-ray electron, proton, and helium spectra of the remnant. The results for the ratio of the number densities of protons and electrons (R = 160 at 1 GeV), the total energy in cosmic rays (E_cr = 1 x 10^50 ergs), and the spectral index of the electrons at 1 GeV (Gamma_e = 2.14 +/- 0.12) are consistent with the hypothesis that Galactic cosmic rays are accelerated predominantly in the shocks of supernova remnants. Yet, the remnant may or may not accelerate nuclei to energies as high as the energy of the "knee," depending on the reason why the maximum energy of the electrons is only 10 TeV.Comment: 41 pages, 9 figures, accepted for publication in ApJ in Septembe

The fundamental constants and their variation: observational status and theoretical motivations

This article describes the various experimental bounds on the variation of the fundamental constants of nature. After a discussion on the role of fundamental constants, of their definition and link with metrology, the various constraints on the variation of the fine structure constant, the gravitational, weak and strong interactions couplings and the electron to proton mass ratio are reviewed. This review aims (1) to provide the basics of each measurement, (2) to show as clearly as possible why it constrains a given constant and (3) to point out the underlying hypotheses. Such an investigation is of importance to compare the different results, particularly in view of understanding the recent claims of the detections of a variation of the fine structure constant and of the electron to proton mass ratio in quasar absorption spectra. The theoretical models leading to the prediction of such variation are also reviewed, including Kaluza-Klein theories, string theories and other alternative theories and cosmological implications of these results are discussed. The links with the tests of general relativity are emphasized.Comment: 56 pages, l7 figures, submitted to Rev. Mod. Phy

Universal health coverage from multiple perspectives: a synthesis of conceptual literature and global debates

Background: There is an emerging global consensus on the importance of universal health coverage (UHC), but no unanimity on the conceptual definition and scope of UHC, whether UHC is achievable or not, how to move towards it, common indicators for measuring its progress, and its long-term sustainability. This has resulted in various interpretations of the concept, emanating from different disciplinary perspectives. This paper discusses the various dimensions of UHC emerging from these interpretations and argues for the need to pay attention to the complex interactions across the various components of a health system in the pursuit of UHC as a legal human rights issue. Discussion: The literature presents UHC as a multi-dimensional concept, operationalized in terms of universal population coverage, universal financial protection, and universal access to quality health care, anchored on the basis of health care as an international legal obligation grounded in international human rights laws. As a legal concept, UHC implies the existence of a legal framework that mandates national governments to provide health care to all residents while compelling the international community to support poor nations in implementing this right. As a humanitarian social concept, UHC aims at achieving universal population coverage by enrolling all residents into health-related social security systems and securing equitable entitlements to the benefits from the health system for all. As a health economics concept, UHC guarantees financial protection by providing a shield against the catastrophic and impoverishing consequences of out-of-pocket expenditure, through the implementation of pooled prepaid financing systems. As a public health concept, UHC has attracted several controversies regarding which services should be covered: comprehensive services vs. minimum basic package, and priority disease-specific interventions vs. primary health care. Summary: As a multi-dimensional concept, grounded in international human rights laws, the move towards UHC in LMICs requires all states to effectively recognize the right to health in their national constitutions. It also requires a human rights-focused integrated approach to health service delivery that recognizes the health system as a complex phenomenon with interlinked functional units whose effective interaction are essential to reach the equilibrium called UHC