Gluon propagator in diffractive scattering

In this work, we perform a comparison of the employ of distinct gluon propagators with the experimental data in diffractive processes, $pp$ elastic scattering and light meson photo-production. The gluon propagators are calculated through non-perturbative methods, being justified their use in this class of events, due to the smallness of the momentum transfer. Our results are not able to select the best choice for the modified gluon propagator among the analyzed ones, showing that the application of this procedure in this class of high energy processes, although giving a reasonable fit to the experimental data, should be taken with same caution.Comment: 14 pages, 4 figures, accepted for publication in Int. J. Mod. Phys. A (uses ws-ijmpa.cls). Authors correcte

DNA aberrations in urinary bladder cancer detected by flow cytometry and FISH

Detection of molecular alterations is of potential significance for diagnosis and prognosis in bladder cancer. Fluorescence in situ hybridization (FISH) allows visualization and quantitation of genes and chromosomes on a cell by cell level and can easily be applied to urinary cells. To evaluate the sensitivity of FISH for detection of DNA aberrations in bladder cancer, formalin-fixed tissues of 293 tumors were examined by FISH and flow cytometry (FCM). Centromere probes for the chromosomes X, Y, 1, 7, 9, and 17 were used for FISH analysis. FISH was more sensitive for detection of quantitative DNA aberrations than FCM. An aberration of at least one chromosome was found in 107 of 108 tumors (99%), which were tetraploid, aneuploid, or multiploid, and in 29 of 49 tumors (59%), which were diploid, by FCM. The frequency of FISH aberrations showed greater differences between pTa (47%) and pT1 tumors (85%;P<0.0001) than between stages pT1 and pT2-4 (98%). The marked genetic difference between pTa and pT1 tumors argues against the concept of grouping pTa and pT1 tumors together as "superficial bladder cancer.” The frequency of tumors with chromosomal aberrations detected by FISH increased with the number of chromosomes examined. Aneusomy was seen in 68% of grade 1 tumors examined for ≥4 chromosomes, suggesting that the cytological diagnosis of bladder cancer recurrences could be substantially improved by FIS