14 research outputs found
Retrospective Comparison of Non-Skin-Sparing Mastectomy and Skin-Sparing Mastectomy with Immediate Breast Reconstruction
Background. We compared Skin-sparing mastectomy (SSM) with immediate breast reconstruction and Non-skin-sparing mastectomy (NSSM), various types of incision in SSM.
Method. Records of 202 consecutive breast cancer patients were reviewed retrospectively. Also in the SSM, three types of skin incision were used. Type A was a periareolar incision with a lateral extension, type B was a periareolar incision and axillary incision, and type C included straight incisions, a small elliptical incision (base line of nipple) within areolar complex and axillary incision.
Results. Seventy-three SSMs and 129 NSSMs were performed. The mean follow-up was 30.0 (SSM) and 41.1 (NSSM) months. Respective values for the two groups were: mean age 47.0 and 57; seven-year cumulative local disease-free survival 92.1% and 95.2%; post operative skin necrosis 4.1% and 3.1%. In the SSM, average areolar diameter in type A & B was 35.4 mm, 43.0 mm in type C and postoperative nipple-areolar plasty was performed 61% in type A & B, 17% in type C, respectively.
Conclusion. SSM for early breast cancer is associated with low morbidity and oncological safety that are as good as those of NSSM. Also in SSM, Type C is far superior as regards cost and cosmetic outcomes
Initial experience with contrast-enhanced ultrasonography in follow up assessment of small breast cancer treated by cryoablation
BackgroundCryoablation (CA) is a nonsurgical focal therapy for small tumours. To detect residual or relapsed tumour after CA of renal cancer, contrast-enhanced imaging is generally used to identify tumour blood flow, but no definitive criteria are established for such follow-up after CA of breast cancer.AimsThe aim of this study was to compare the usefulness of contrast-enhanced ultrasonography (CEUS) and magnetic resonance (MR) imaging for assessing residual tumours and local relapse following CA of small breast cancers.Methods We enrolled 4 patients treated by CA at our institution between January 2015 and December 2016 for luminal A breast cancer with maximum tumour size of 1.5cm and neither distant metastasis nor metastatic findings in sentinel lymph node biopsy, who underwent CEUS and MR imaging before CA. In addition to our standard postoperative follow-up for breast cancer, these patients underwent CEUS every 3 months and MR imaging every 6 months after CA.Results Six months after CA, no patient showed enhancement at the lesion site on MR imaging, but there were two with continued enhancement on CEUS. They underwent vacuum-assisted breast biopsy under US guidance followed by histopathological examination of tissue that identified no malignancy.ConclusionOur findings of focal enhancement within ablated breast tissue in CEUS after CA is likely attributable to the much higher sensitivity of CEUS to that of other modalities to even slight vascularization. Further investigation in more patients is needed to clarify the utility of CEUS to detect residual or relapsed tumour after CA of small breast cancer
Clinical comparison of four types of skin incisions for skin-sparing mastectomy and immediate breast reconstruction
Discovery of a spiral-host episodic radio-galaxy
We report the discovery of a unique radio galaxy at z=0.137, which could
possibly be the second spiral-host large radio galaxy and also the second
triple-double episodic radio galaxy. The host galaxy shows signs of recent star
formation in the UV but is optically red and is the brightest galaxy of a
possible cluster. The outer relic radio lobes of this galaxy, separated by ~1
Mpc, show evidence of spectral flattening and a high fraction of linear
polarisation. We interpret that these relic lobes have experienced
re-acceleration of particles and compression of the magnetic field due to
shocks in the cluster outskirts. From the morphology of the relics and galaxy
distribution, we argue that re-acceleration is unlikely to be due to a
cluster-cluster merger and suggest the possibility of accretion shocks. The
source was identified from SDSS, GALEX, NVSS and FIRST survey data but we also
present follow up optical observations with the Lulin telescope and 325 MHz low
frequency radio observations with the GMRT. We briefly discuss the scientific
potential of this example in understanding the evolution of galaxies and
clusters by accretion, mergers, star formation, and AGN feedback.Comment: Accepted for publication in MNRAS Letter
Initial experience with contrast-enhanced ultrasonography in follow up assessment of small breast cancer treated by cryoablation
Background
Cryoablation (CA) is a nonsurgical focal therapy for small
tumours. To detect residual or relapsed tumour after CA of
renal cancer, contrast - enhanced imaging is generally used to identify tumour blood flow, but no definitive criteria are established for such follow-up after CA of breast cancer.
Aims
The aim of this study was to compare the usefulness
of contrast-enhanced ultrasonography (CEUS) and magnetic resonance (MR) imaging for assessing residual
tumours and local relapse following CA of small breast cancers.
Methods
We enrolled 4 patients treated by CA at our institution
between January 2015 and December 2016 for luminal A
breast cancer with maximum tumour size of 1.5cm and
neither distant metastasis nor metastatic findings in
sentinel lymph node biopsy, who underwent CEUS and MR imaging before CA. In addition to our standard postoperative follow-up for breast cancer, these patients underwent CEUS every 3 months and MR imaging every 6 months after CA.
Results
Six months after CA, no patient showed enhancement at the
lesion site on MR imaging, but there were two with
continued enhancement on CEUS. They underwent vacuum
-assisted breast biopsy under US guidance followed by histopathological examination of tissue that identified no
malignancy.
Conclusion
Our findings of focal enhancement within ablated breast
tissue in CEUS after CA is likely attributable to the much
higher sensitivity of CEUS to that of other modalities to even
slight vascularization. Further investigation in more patients
is needed to clarify the utility of CEUS to detect residual or relapsed tumour after CA of small breast cancer