Textual affinity of Origen\u27s gospel text in his commentary and homilies on Luke

https://place.asburyseminary.edu/ecommonsatsdissertations/2057/thumbnail.jp

Issues for Earthquake Disaster Prevention Awareness and Earthquake Disaster Prevention Education of Students Who Want to Become Childcare Workers

　保育者志望学生を対象に，保育における地震防災に関する意識や子どもへの地震防災教育の実践に関する課題等について質問紙調査を行った。その結果，実習経験の有無に関わらず，保育職に就く前に地震防災について理解しておく必要性について強く認識している傾向があることが分かった。また，実習経験の有無で差異が生じる意識もあることが確認できた。地震防災教育を実践する上での教育内容や自身の課題については，実習経験のない学生は，一般論的な内容で具体性に欠け，幅広い視点で防災教育を捉えていることが分かった。一方，実習経験のある学生は，保育現場の状況や子どもの発達過程を考慮した保育者としての視点や願いの表れた課題を持っている傾向があることが示唆された

Backflow and dissipation during the quantum decay of a metastable Fermi liquid

The particle current in a metastable Fermi liquid against a first-order phase transition is calculated at zero temperature. During fluctuations of a droplet of the stable phase, in accordance with the conservation law, not only does an unperturbed current arise from the continuity at the boundary, but a backflow is induced by the density response. Quasiparticles carrying these currents are scattered by the boundary, yielding a dissipative backflow around the droplet. An energy of the hydrodynamic mass flow of the liquid and a friction force exerted on the droplet by the quasiparticles have been obtained in terms of a potential of their interaction with the droplet.Comment: 5 pages (REVTeX), to be published in Phys. Rev.

22510 IMPROVEMENT OF THE DAMPING CONSTANTS FOR SEISMIC DESIGN OF PIPING SYSTEM FOR NPP

ABSTRACT The present design damping constants for nuclear power plant (NPP)'s piping system in Japan were developed through discussion among expert researchers, electric utilities and power plant manufactures. They are standardized in "Technical guidelines for seismic design of Nuclear Power Plants" (JEAG 4601-1991 Supplemental Edition). But some of the damping constants are too conservative because of a lack of experimental data. To improve this excessive conservatism, piping systems supported by U-bolts were chosen and U-bolt support element test and piping model excitation test were performed to obtain proper damping constants. The damping mechanism consists of damping due to piping materials, damping due to fluid interaction, damping due to plastic deformation of piping and supports, and damping due to friction and collision between piping and supports. Because the damping due to friction and collision was considered to be dominant, we focused our effort on formulating these phenomena by a physical model. The validity of damping estimation method was confirmed by comparing data that was obtained from the elemental tests and the actual scale piping model test. New design damping constants were decided from the damping estimations for piping systems in an actual plant. From now on, we will use the new design damping constants for U-bolt support piping systems, which were proposed from this study, as a standard in the Japanese piping seismic design

Cystic Lymphangioma of the Pancreas with Spontaneous Rupture: Report of a Case

Lymphangioma is a benign and congenital malformation of the lymphatic system. Most lymphangiomas are preferentially located in the head and neck region. The abdominal organs are uncommon sites of origin. Several cases of lymphangioma in abdominal organs were reported, however, the pancreas is one of the rarest origins. Generally, intra-abdominal lymphangioma is asymptomatic and found incidentally, but in some cases, the patient complains of abdominal distension or a palpable mass. We describe the case of a 38-year-old male who presented with sudden-onset upper abdominal pain. Rupture of a cystic tumor of the pancreatic head was suspected, based on the findings of computed tomography, magnetic resonance imaging and endoscopic ultrasonography. Subtotal stomach-preserving pancreaticoduodenectomy was undertaken. The tumor, which was 4 × 4.5 × 8 cm in size, was pathologically diagnosed as a cystic lymphangioma. In conclusion, pancreatic lymphangioma is mostly asymptomatic, a ruptured case causing ‘acute abdomen’ has never been reported. Since lymphangioma is benign, it could be observed with accurate diagnosis. The surgical indication would be limited to cases of symptomatic lymphangiomas

Clinical Validation of a Multiplex Kit for RAS Mutations in Colorectal Cancer: Results of the RASKET (RAS KEy Testing) Prospective, Multicenter Study

AbstractBackgroundRAS (KRAS and NRAS) testing is required to predict anti-epidermal growth factor receptor (EGFR) treatment efficacy in metastatic colorectal cancer (CRC). Although direct sequencing (DS) with manual microdissection (MMD) is widely used, a diagnostic kit providing rapid detections of RAS mutations would be clinically beneficial. We evaluated the MEBGENTM RASKET KIT (RASKET KIT), a multiplex assay using PCR-reverse sequence specific oligonucleotide and xMAP® technology to concurrently detect exon 2, 3, and 4 RAS mutations in a short turnaround time (4.5h/96-specimens).MethodsFormalin-fixed paraffin-embedded (FFPE) tissues were obtained from 308 consenting patients with histologically-confirmed CRC at six hospitals in Japan. For the RASKET KIT, we used only 50–100ng DNA from each FFPE specimen not processed by MMD. The primary endpoint was the concordance rate between RAS mutations identified with the RASKET KIT and two reference assays (DS with MMD and TheraScreen® K-RAS Mutation Kit). As the secondary endpoints, we evaluated the concordance rate between DS and the RASKET KIT for RAS mutations in the wild-type KRAS exon 2 population and the genotyping performance of the RASKET KIT compared with DS.FindingsAmong 307 analyzable specimens, the reference assays detected 140 (45.6%, 140/307) RAS mutations: 111 KRAS exon 2 and 29 other (minor) RAS mutations. The RASKET KIT detected 143 (46.6%, 143/307) mutations: 114 KRAS exon 2 and 29 minor RAS mutations. The between-method concordance rate was 96.7% (297/307) (95% CI: 94.1–98.4%). Minor RAS mutations were detected in 15.7% (30/191) of the wild-type KRAS exon 2 population (n=191); the concordance rate was 98.4% (188/191) (95% CI: 95.5–99.7%). The concordance rate of RAS genotyping was 100% (139/139) (95% CI: 97–100%).InterpretationThe RASKET KIT provides rapid and precise detections of RAS mutations and consequently, quicker and more effective anti-EGFR therapy for CRC (Study ID: UMIN000011784).FundingMedical & Biological Laboratories Co., Ltd. (MBL). MBL had roles in study design, data collection, data analysis, and writing of the report for the study