Hospital volume and mortality after transjugular intrahepatic portosystemic shunt creation in the United States

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141487/1/hep29354-sup-0001-suppinfo1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141487/2/hep29354_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141487/3/hep29354.pd

eBay users form stable groups of common interest

Market segmentation of an online auction site is studied by analyzing the users' bidding behavior. The distribution of user activity is investigated and a network of bidders connected by common interest in individual articles is constructed. The network's cluster structure corresponds to the main user groups according to common interest, exhibiting hierarchy and overlap. Key feature of the analysis is its independence of any similarity measure between the articles offered on eBay, as such a measure would only introduce bias in the analysis. Results are compared to null models based on random networks and clusters are validated and interpreted using the taxonomic classifications of eBay categories. We find clear-cut and coherent interest profiles for the bidders in each cluster. The interest profiles of bidder groups are compared to the classification of articles actually bought by these users during the time span 6-9 months after the initial grouping. The interest profiles discovered remain stable, indicating typical interest profiles in society. Our results show how network theory can be applied successfully to problems of market segmentation and sociological milieu studies with sparse, high dimensional data.Comment: Major revision of the manuscript. Methodological improvements and inclusion of analysis of temporal development of user interests. 19 pages, 12 figures, 5 table

PinnerSage: Multi-Modal User Embedding Framework for Recommendations at Pinterest

Latent user representations are widely adopted in the tech industry for powering personalized recommender systems. Most prior work infers a single high dimensional embedding to represent a user, which is a good starting point but falls short in delivering a full understanding of the user's interests. In this work, we introduce PinnerSage, an end-to-end recommender system that represents each user via multi-modal embeddings and leverages this rich representation of users to provides high quality personalized recommendations. PinnerSage achieves this by clustering users' actions into conceptually coherent clusters with the help of a hierarchical clustering method (Ward) and summarizes the clusters via representative pins (Medoids) for efficiency and interpretability. PinnerSage is deployed in production at Pinterest and we outline the several design decisions that makes it run seamlessly at a very large scale. We conduct several offline and online A/B experiments to show that our method significantly outperforms single embedding methods.Comment: 10 pages, 7 figure

Young Muslim women's experiences of Islam and physical education in Greece and Britain: a comparative study

Previous research suggests that Muslim women can experience particular problems when taking physical education (PE) lessons, for example with dress codes, mixed-teaching and exercise during Ramadan; and they can face restrictions in extra-curricular activities for cultural and religious reasons. The area is under-researched and there is little evidence of comparative studies that explore similarities and differences in cross-national experiences, which is the aim of this paper. Two studies conducted in Greece and Britain that explored the views of Muslim women on school experiences of physical education are compared. Both studies focused on diaspora communities, Greek Turkish girls and British Asian women, living in predominantly non-Muslim countries. Growing concerns about global divisions between 'Muslims and the West' make this a particularly pertinent study. Qualitative data were collected by interviews with 24 Greek Muslim women, and 20 British Muslim women. \ud <P> \ud Physical education has national curriculum status and a similar rationale in both countries but with different cultures of formality and tradition, which impacted on pupils' experiences. Data suggested that Greek and British groups held positive views towards physical education but were restricted on their participation in extra-curricular activities. For the British women religious identity and consciousness of Islamic requirements were more evident than for the Greek women. Differences in stages of acculturation, historical and socio-cultural contexts contributed to less problematic encounters with physical education for Greek Muslims who appeared more closely assimilated into the dominant culture

Purification and medium optimization of α-amylase from Bacillus subtilis 168

α-Amylase was first time isolated and purified from Bacillus subtilis 168 (1A1). Purified α-amylase fraction showed a single protein band with a molecular weight of 55 kD. Chemical characterization of the purified α-amylase revealed optimum amylolytic activity at 37°C and pH 7.0 using starch as substrate. It was stable at pH 5.0 to 9.0 and at temperatures 25–70°C. Culture conditions were optimized by using statistics-based experimental designs to enhanced α-amylase (EC.3.2.1.1) production. A two level fractional factorial Plackett-Burman design was used for the preliminary screening significant media components and conditions. Response surface methodology (RSM) involving a 24 full-factorial central composite design (CCD) and a second-order polynomial equation was then employed to identify the relationship between the α-amylase yield and the four significant variables. Optimal levels of the significant variables for the maximum α-amylase yield were starch 2.55 g/l, yeast extract 8.4 g/l, sodium chloride 8.1% and 48 h of incubation. Mean value of α-amylase yield was 639.7 IU/ml, which was in excellent agreement with the predicted value (633.5 IU/ml).Key words: Bacillus, α-amylase, optimization, Plackett-Burman design, response surface methodology

A comparison of atmospheric composition using the Carbon Bond and Regional Atmospheric Chemistry Mechanisms

We incorporate the recently developed Regional Atmospheric Chemistry Mechanism (version 2, RACM2) into the Community Multiscale Air Quality modeling system for comparison with the existing 2005 Carbon Bond mechanism with updated toluene chemistry (CB05TU). Compared to CB05TU, RACM2 enhances the domain-wide monthly mean hydroxyl radical concentrations by 46% and nitric acid by 26%. However, it reduces hydrogen peroxide by 2%, peroxyacetic acid by 94%, methyl hydrogen peroxide by 19%, peroxyacetyl nitrate by 40%, and organic nitrate by 41%. RACM2 enhances ozone compared to CB05TU at all ambient levels. Although it exhibited greater overestimates at lower observed concentrations, it displayed an improved performance at higher observed concentrations. The RACM2 ozone predictions are also supported by increased ozone production efficiency that agrees better with observations. Compared to CB05TU, RACM2 enhances the domain-wide monthly mean sulfate by 10%, nitrate by 6%, ammonium by 10%, anthropogenic secondary organic aerosols by 42%, biogenic secondary organic aerosols by 5%, and in-cloud secondary organic aerosols by 7%. Increased inorganic and organic aerosols with RACM2 agree better with observed data. Any air pollution control strategies developed using the two mechanisms do not differ appreciably

Development of real-time density feedback control on MAST-U in L-mode

In this paper we report on the development and demonstration of density feedback control for MAST-U. Sinusoidal perturbations are used to measure the frequency response from a deuterium gas valve (actuator) to line-integrated core electron density measured by the interferometer (sensor). In the frequency range relevant for control design, only two system-identification experiments were needed to regress a first-order dynamic model. This control-oriented model informs the offline design of a proportional integral controller with the established loop-shaping controller design method. After offline verification of the controller implementation, control is demonstrated by experimentally tracking a staircase reference for the line-integrated electron density. This paper demonstrates the efficiency of controller design using system-identification and loop-shaping, providing reliable density control for MAST-U.</p

Challenges and Prospects of Sustainable Groundwater

Abstract In Pakistan, on-demand availability of groundwater has transformed the concept of low and uncertain crop yields into more assured crop production. Increased crop yields has resulted in food security and improved rural livelihoods. However, this growth has also led to problems of overdraft, falling watertables and degradation of groundwater quality, and yields generally remain well below potential levels. Over the last three decades, Pakistan has tried several direct and indirect management strategies for groundwater management. However the success has been limited. This paper argues that techno-institutional approaches such as introducing water rights, direct or indirect pricing and permit systems are fraught with difficulties in Pakistan due to its high population density and multitude of tiny users. Therefore there is a need to develop frameworks and management tools that are best suited to Pakistani needs. Pakistan should follow both supply and demand management approaches. For demand management, adoption of water conservation technologies, revision of existing cropping patterns and exploration of alternate water resources should be encouraged. For supply management, implementation of the groundwater regulatory frameworks developed by Provincial Irrigation and Drainage Authorities (PIDAs) and introduction of institutional reforms to enhance effective coordination between different organizations responsible for the management of groundwater resources should be given priority