42 research outputs found

    Tecnología vs. Comercio : una aplicación de fairness

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    Este trabajo se propone estudiar la percepción de fairness de los efectos de la tecnología y el comercio en el mercado laboral. El objetivo es generar evidencia acerca de la aceptabilidad de parte de los agentes económicos de un set de situaciones generadas por ambos fenómenos, para estudiar si efectivamente la percepción de fairness varía entre ambas situaciones. ¿Es el desempleo causado por apertura comercial considerado más aceptable o más inaceptable que el desempleo causado por el cambio tecnológico? Esa es la pregunta crucial de nuestra investigación

    The interplay between partisanship, forecasted COVID-19 deaths, and support for preventive policies

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    The COVID-19 pandemic is a global crisis that has forced governments around the world to implement large-scale interventions such as school closures and national lockdowns. Previous research has shown that partisanship plays a major role in explaining public attitudes towards these policies and beliefs about the intensity of the crisis. However, it remains unclear whether and how partisan differences in policy support relate to partisan gaps in beliefs about the number of deaths that the pandemic will cause. Do individuals who forecast fewer COVID-19 deaths show less agreement with preventive measures? How does partisanship correlate with people’s beliefs about the intensity of the crisis and their support for COVID-19 policies? Here, we sought to answer these questions by performing a behavioral experiment in Argentina (Experiment 1, N = 640) and three quasi-replication studies in Uruguay (Experiment 2, N = 372), Brazil (Experiment 3, N = 353) and the United States (Experiment 4, N = 630). In all settings, participants forecasted the number of COVID-19 deaths in their country after considering either a high or low number, and then rated their agreement with a series of interventions. This anchoring procedure, which experimentally induced a large variability in the forecasted number of deaths, did not modify policy preferences. Instead, each experiment provided evidence that partisanship was a key indicator of the optimism of forecasts and the degree of support for COVID-19 policies. Remarkably, we found that the number of forecasted deaths was robustly uncorrelated with participants’ agreement with preventive measures designed to prevent those deaths. We discuss these empirical observations in the light of recently proposed theories of tribal partisan behavior. Moreover, we argue that these results may inform policy making as they suggest that even the most effective communication strategy focused on alerting the public about the severity of the pandemic would probably not translate into greater support for COVID-19 preventive measures.Fil: Freira Polleri, Maria Lucia. Universidad Torcuato Di Tella. Escuela de Negocios; ArgentinaFil: Sartorio, Marco. Universidad Torcuato Di Tella. Escuela de Negocios; ArgentinaFil: Boruchowicz, Cynthia. Banco Interamericano de Desarrollo.; Estados UnidosFil: Lopez Boo, Florencia. Banco Interamericano de Desarrollo.; Estados UnidosFil: Navajas Ahumada, Joaquin Mariano. Universidad Torcuato Di Tella. Escuela de Negocios; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

    GH Responsiveness to Combined GH-Releasing Hormone and Arginine Administration in Obese Patients with Fibromyalgia Syndrome

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    Reportedly, fibromyalgia (FM) is frequently associated with reduced IGF-1 levels and GH hyporesponsiveness to different GH stimulation tests. Since there is a high prevalence of obesity in FM, and obesity itself is characterized by hyposomatotropism, the aim of this study was to assess IGF-1 levels and GH responsiveness in sixteen severely obese women suffering from FM, who, subdivided into two subgroups on the basis of their age-dependent IGF-1 values (> or <−2 SDS), underwent the combined GHRH plus arginine test. Four out of 16 obese women with FM (25%) had low IGF-1 SDS values, 2 cases of this subgroup (12.5%) failing also to normally respond to the test. Among patients with normal GH responses, 4 showed a delayed GH peak. The subgroup with low IGF-1 SDS values had higher BMI than that with normal IGF-1 SDS. GH peak and area under the curve were not correlated with CRP, ESR, or tender point score, while significant correlations were found with fat-free mass and fat mass. In conclusion, this study shows the existence of a high prevalence of GH-IGF-1 dysfunction in patients with both FM and obesity, presumably as a consequence of the obese rather than fibromyalgic condition

    Hypogonadotropic hypogonadism and pituitary hypoplasia as recurrent features in Ulnar-Mammary syndrome

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    Ulnar-mammary syndrome (UMS) is characterized by ulnar defects, and nipple or apocrine gland hypoplasia, caused by TBX3 haploinsufficiency. Signs of hypogonadism were repeatedly reported, but the mechanisms remain elusive. We aim to assess the origin of hypogonadism in two families with UMS. UMS was suspected in two unrelated probands referred to an academic center with delayed puberty because of the evident ulnar ray and breast defects in their parents. Clinical, biochemical and genetic investigations proved the existence of congenital normosmic IHH (nIHH) associated with pituitary hypoplasia in the two probands who were heterozygous for novel TBX3 pathogenic variants. The mutations co-segregated with delayed puberty, midline defects (nose, teeth and tongue anomalies) and other variable features of UMS in the two families (absent axillary hairs and nipple hypoplasia, asymmetrical features including unilateral ulnar or renal abnormalities). The combined analysis of these findings and of the previous UMS reports showed delayed puberty and other signs of hypogonadism in 79 and 37% of UMS males, respectively. Proband 1 was followed up to adulthood with persistence of nIHH. In conclusion, UMS should be suspected in patients with delayed puberty and midline defects, including pituitary hypoplasia, in the presence of mild cues for TBX3 mutation, even in the absence of limb malformations. In addition, TBX3 should be included among candidate genes for congenital nIHH

    Are Patients with Polycystic Ovarian Syndrome Ideal Candidates for Oocyte Donation?

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    Background. The use of donated oocytes for in vitro fertilization treatment in patients with ovarian failure is universally recognized. But would patients with polycystic ovarian syndrome (PCOS) be a good choice for egg donation programs? Objective. Comparing the pregnancy rates of egg receptors from donor patients diagnosed with PCOS to receptors from donors without PCOS. Design. Retrospective cohort study. Methods. A total of 234 patients who had undergone egg reception program were separated into two groups: Group I, receptors from PCOS donors ( = 36); Group II, receptors from donors without PCOS ( = 198). Medical records were reviewed and the fertilization, implantation, and pregnancy rates were calculated. Results. PCOS patients had an average of 3.23 more oocytes retrieved, but there were no differences in the number of mature oocytes that were used for donation between the groups. We also observed that the number of transferred embryos was also not significantly different, as well as the fertilization and implantation rates. The clinical pregnancy rates were not significantly different: 28% and 26% in Group I and Group II, respectively. Conclusions. Women with PCOS should not be excluded from egg donation programs

    Preliminary Assessment of Radiolysis for the Cooling Water System in the Rotating Target of {SORGENTINA}-{RF}

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    The SORGENTINA-RF project aims at developing a 14 MeV fusion neutron source featuring an emission rate in the order of 5-7 x 10(13) s(-1). The plant relies on a metallic water-cooled rotating target and a deuterium (50%) and tritium (50%) ion beam. Beyond the main focus of medical radioisotope production, the source may represent a multi-purpose neutron facility by implementing a series of neutron-based techniques. Among the different engineering and technological issues to be addressed, the production of incondensable gases and corrosion product into the rotating target deserves a dedicated investigation. In this study, a preliminary analysis is carried out, considering the general layout of the target and the present choice of the target material

    The continuity of effect of schizophrenia polygenic risk score and patterns of cannabis use on transdiagnostic symptom dimensions at first-episode psychosis: findings from the EU-GEI study

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    Abstract: Diagnostic categories do not completely reflect the heterogeneous expression of psychosis. Using data from the EU-GEI study, we evaluated the impact of schizophrenia polygenic risk score (SZ-PRS) and patterns of cannabis use on the transdiagnostic expression of psychosis. We analysed first-episode psychosis patients (FEP) and controls, generating transdiagnostic dimensions of psychotic symptoms and experiences using item response bi-factor modelling. Linear regression was used to test the associations between these dimensions and SZ-PRS, as well as the combined effect of SZ-PRS and cannabis use on the dimensions of positive psychotic symptoms and experiences. We found associations between SZ-PRS and (1) both negative (B = 0.18; 95%CI 0.03–0.33) and positive (B = 0.19; 95%CI 0.03–0.35) symptom dimensions in 617 FEP patients, regardless of their categorical diagnosis; and (2) all the psychotic experience dimensions in 979 controls. We did not observe associations between SZ-PRS and the general and affective dimensions in FEP. Daily and current cannabis use were associated with the positive dimensions in FEP (B = 0.31; 95%CI 0.11–0.52) and in controls (B = 0.26; 95%CI 0.06–0.46), over and above SZ-PRS. We provide evidence that genetic liability to schizophrenia and cannabis use map onto transdiagnostic symptom dimensions, supporting the validity and utility of the dimensional representation of psychosis. In our sample, genetic liability to schizophrenia correlated with more severe psychosis presentation, and cannabis use conferred risk to positive symptomatology beyond the genetic risk. Our findings support the hypothesis that psychotic experiences in the general population have similar genetic substrates as clinical disorders

    Machina Tecnologia dell'antica Roma. Catalogo della Mostra, Roma Museo della Civiltà Romana

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    Tecnologia nella Roma antica; studio analitico dei diversi saperi tecnici e artigianali sulla base monumenti e oggietti archeologici, contesti, cultura materiali e ricostruzion

    El trabajo se transforma: Implicancias de la automatización y el comercio en el mercado laboral

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    El experimento muestra que en toda la región la pérdida del empleo por la apertura comercial es menos aceptable que el desempleo ocasionado por el avance de las tecnologías. El 46% de los participantes considera aceptable prohibir la importación de ropa para preservar el empleo, mientras que solo el 33% aceptaría prohibir el uso de tecnologías con este fin. · Si se introduce al gobierno como responsable de las medidas que generarían pérdidas de empleo, el nivel de aceptación de las tecnologías y de la apertura comercial se equipara. · El estudio corrobora que, debido al sesgo de contabilidad mental, las personas suelen ser irracionales para categorizar el uso del dinero. Por ejemplo, la mayoría considera más aceptable recibir un curso de capacitación de 300 dólares que recibir un bonus por ese mismo monto.Fil: Sartorio, Marco. Universidad Torcuato Di Tella; ArgentinaFil: Navajas Ahumada, Joaquin Mariano. Universidad Torcuato Di Tella; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin
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