Water Scarcity and Virtual Water Trade in the Mediterranean

Virtual water trade refers to the implicit content of water in the production of goods and services. When trade is undertaken, there is an implicit exchange of water. Furthermore, when water gets scarce, water intensive goods become more expensive to produce and the economy compensates through higher water imports.This paper is about applying the concept of virtual water to the problem of future water scarcity in the Mediterranean area, also induced by the climate change. The aim is assessing to what extent water trade is a viable adaptation option to the problem of water scarcity. To this end, a computable general equilibrium model is extended with satellite data on sectoral water consumption, and used to assess future scenarios of water availability.It is found that virtual trade may curb the negative effect of water scarcity, yet the consequences in terms of income and welfare remain quite significant, especially for some regions.Computable General Equilibrium Models, Water, Virtual Water, Water Scarcity, Climate Change

UNDULY ENHANCED RESPONSE TO TOLVAPTAN IN A WOMAN SHOWING SYNDROME OF INAPPROPRIATE ANTIDIURETIC HORMONE SECRETION: AN INVESTIGATION OF POSSIBLE CAUSES

Objective: To investigate possible causes of an excessive response to tolvaptan in a woman with syndrome of inappropriate antidiuretic hormone secretion (SIADH). Methods: A 32-year-old woman was admitted to our cardiologic unit 3 months after delivery for hypertension and severe hyponatremia (120 mEq/L). Two hyponatremic episodes had already been documented in her medical history. SIADH was diagnosed and treatment with tolvaptan, an arginine vasopressin (AVP) antagonist, was instituted. After the first 15-mg dose, excessive polyuria (1 L/ hour) and a rapid increase in serum sodium (13 mEq/L in 8 hours) occurred, so that therapy was stopped and restarted 2 days later at a reduced dose (5 mg). This level was effective and well tolerated. To explore the possible pharmacokinetic and pharmacodynamic mechanisms underlying the patient\u2019s hyperresponsiveness, the following tests were carried out: (1) in vivo phenotyping of CYP3A4 activity, the cytochrome responsible for tolvaptan metabolism, with two probe drugs (omeprazole and dextromethorphan); and (2) search for mutations in genes involved in AVP signaling (AVP, V2R, AQP2, OXT)

genetic parameters of two methods of scoring cow fighting ability

In this study, two different methods of scoring were implemented and compared in reason to assign a correct phenotypic value to cow fighting ability, and the variance components of the trait were estimated. Moreover, it was investigated the correlation of the estimated breeding values (EBVs) for fighting with the EBVs for the linear type traits muscularity. A scoring method mainly based on position (PS) and a method considering opponents' performances (CPS) were compared and used in genetic analyses. A correlation of 0.75 between EBVs associated to PS and CPS was obtained, and ANOVAs considering alternatively PS and CPS indicated almost the same magnitude of the different sources of variation included (R2=0.50 and 0.52 for PS and CPS, respectively). Heritability estimates with the REML method were 0.099 (S.E.=0.005) for PS and 0.034 (S.E.=0.007) for CPS. Pearson and Spearman correlations between both indexes and ranks were no significant. Finally, an evaluation of the fitness of the two models revealed that PS is the better system for scoring, although CPS was designed to account also for the opponents

Exploring manual asymmetries during grasping: a dynamic causal modeling approach

Recording of neural activity during grasping actions in macaques showed that grasp-related sensorimotor transformations are accomplished in a circuit constituted by the anterior part of the intraparietal sulcus (AIP), the ventral (F5) and the dorsal (F2) region of the premotor area. In humans, neuroimaging studies have revealed the existence of a similar circuit, involving the putative homolog of macaque areas AIP, F5 and F2. These studies have mainly considered grasping movements performed with the right dominant hand and only a few studies have measured brain activity associated with a movement performed with the left non-dominant hand. As a consequence of this gap, how the brain controls for grasping movement performed with the dominant and the non-dominant hand still represents an open question. A functional resonance imaging experiment (fMRI) has been conducted, and effective connectivity (Dynamic Causal Modelling, DCM) was used to assess how connectivity among grasping-related areas is modulated by hand (i.e., left and right) during the execution of grasping movements towards a small object requiring precision grasping. Results underlined boosted inter-hemispheric couplings between dorsal premotor cortices during the execution of movements performed with the left rather than the right dominant hand. More specifically, they suggest that the dorsal premotor cortices may play a fundamental role in monitoring the configuration of fingers when grasping movements are performed by either the right and the left hand. This role becomes particularly evident when the hand less-skilled (i.e., the left hand) to perform such action is utilized. The results are discussed in light of recent theories put forward to explain how parieto-frontal connectivity is modulated by the execution of prehensile movements

The cost of participation: An analysis of the financial dimensions of participatory budgets in Portugal

Participatory budgeting (PB) is a democratic innovation that allows citizens to deliberate about a share of the public budget. Portugal was one of the most influent countries in this field in the last decade, as PB was implemented at multiple levels. However, few studies have made in-depth research on the financial dimensions of PB, which raises interest as to whether and how citizens' voice has had a significant impact on policy-making. To fill in this gap, this article considers the financial asset of local, regional, and national PBs in Portugal up to the disruption of the COVID-19 pandemic. Our methodological approach relies on both quantitative data analyzed through Geographical Information Systems and descriptive statistics, and qualitative data retrieved from document analysis. Findings are discussed through four different stages of dissemination in the country, and show that despite significant advancements in this field, impacts in the financial dimensions lay behind expectations.info:eu-repo/semantics/publishedVersio

An intelligent curve warning system for powered two wheel vehicles

This article illustrates a novel Curve Warning system for motorcycles which has been developed in the SAFERIDER project (www.saferider-eu.org) of the 7th EU FP, among other Advanced Rider Assistance Systems. The Curve Warning function (CW) described here follows a holistic approach, which combines road geometry, motorcycle dynamics, rider input and riding styles. The warning strategy is based on the correction of longitudinal dynamics derived from a previewed ideal manoeuvre (reference manoeuvre) continuously computed from the actual state of the vehicle. Under normal driving conditions the reference manoeuvre matches the rider's and no correction is needed and no warning is given. But if large differences between actual and ideal accelerations are found the rider is warned to decelerate or brake. As soon as the correct value of deceleration is achieved the warning disappears, improving system acceptability. Warnings are given to the rider via an HMI, which uses a haptic accelerator throttle, a vibrating glove and helmet, and a visual display

Genetic correlations of fighting ability with somatic cells and longevity in cattle.

The success in competitions may be stressful for animals and costly in terms of immune functions and longevity. Focusing on Aosta Chestnut and Aosta Black Pied cattle, selected for their fighting ability in traditional competitions, this study investigated the genetic relationships of fighting ability with udder health traits (somatic cell score and two threshold traits for somatic cells), longevity (length of productive life and number of calvings) and test-day milk, fat and protein yield. Herdbook information and phenotypic records that have been routinely collected for breeding programs in 16 years were used for the abovementioned traits. Data belonged to 9328 cows and 19 283 animals in pedigree. Single-trait animal model analyses were run using a Gibbs sampling algorithm to estimate the variance components of traits, and bivariate analyses were then performed to estimate the genetic correlations. Moderate positive genetic correlations (ra) were found for fighting ability with somatic cell score (ra=0.255), suggesting that greater fighting ability is genetically related to a detriment in udder health, in agreement with the theory. The high positive genetic correlation between fighting ability and longevity (average ra=0.669) suggests that the economic importance of fighting ability (the winning cows get an higher price at selling) had probably masked the true genetic covariances. The genetic correlation between milk yield traits and fighting ability showed large intervals, but the negative values (average ra=-0.121) agreed with previous research. This study is one of the few empirical studies on genetic correlations for the competitive success v. immune functions and longevity traits. The knowledge of the genetic correlations among productive and functional traits of interest, including fighting ability, is important in animal breeding for a sustainable genetic improvement