A CASE STUDY ON HYPOLIPIDEMIC EFFECT OF A RICE BASED MIX FORTIFIED WITH TERMINALIA ARJUNA,TRIGONELLA FOENUM- GRAECUM AND CINNAMOMUM VERUM

A case study is done to observe the effect of a traditional Assamese breakfast item, namely Sandohguri fortified with Vigna radiate, Terminalia arjuna, Trigonella foenum- graecum and Cinnamomum verum to incorporate hypolipidemic property. As per the nutritive value analysis, 100g of the fortified mix contains 74.75g carbohydrates, 12.92g protein, 1.07g fat (saturated fatty acids 0.30%, monounsaturated fatty acids 0.41% and polyunsaturated fatty acids 0.44%) and 7.13g dietary fibre. Main nutrients with antioxidant properties in the mix are Vitamin A (29.8 IU), Vitamin E (0.57 mg) , Vitamin C (0.16 mg), Selenium (11.2mcg ), Copper (193.4 mcg), Zinc (529.2 mcg), Iron (2531mcg) and Manganese (810.7 mcg). A hyperlipidemic patient without any other medical complications is identified and prescribed to have 90 to 100g of the mix with water/milk and sugar twice daily. A little life style modification with 30 minutes walk is also advised. The patients lipid profile is checked twice within two months from the day of using the mix. The results show an increase in high density lipoprotein (HDL) and reduction in triglyceride, cholesterol, very low density lipoproteins (VLDL)and low density lipoproteins (LDL). Furthermore, the mix is found to be helpful in minimizing various risk factors of Cardio Vascular Diseases, such as hyperlipidemia, atherosclerosis-index, body weight, body mass index and waist hip ratio

DEVELOPMENT AND NUTRITIVE VALUE ANALYSIS OF A HERBAL HYPOLIPIDEMIC HEALTH MIX

Human lifestyle development is related to different physiological or social lifestyle disorders, and hyperlipidemia is one of them which requires rapid attention. Present study is carried out to fortify a traditional Assamese breakfast item Sandoh guri (roasted parboiled rice powder) with green gram Dal, Arjuna, cinnamon and fenugreek to put in hypolipidemic property into it. All ingredients are washed, sundried, roasted and powdered. Powdered parboiled rice, green gram Dal, Arjuna, cinnamon and fenugreek are mixed together in proportion of 70:30:2:2:2.  The proximate composition of the mix and values of a few micronutrients in the mix are found out through standard biochemical methods and calculations using standard nutritive value of ingredients present. Per 100 grams of the mix contain 74.75 g carbohydrates, 12.92 g protein, 1.07 g fat (0.45 g saturated, 0.4 g monounsaturated and 0.51 g polyunsaturated fatty acids) and 7.13 g dietary fibre.  Main nutrients with antioxidant properties in the mix are vitamin A (29.8 IU), vitamin E (0.57 mg), vitamin C (0.16 mg), selenium (11.2 mcg), copper (193.4 mcg), zinc (529.2 mcg), iron (2531 mcg) and manganese (810.7 mcg) .The nutritive value analysis verifies that this developed health mix is a much better breakfast alternative for a hyperlipidemic person  compared  to any other commonly used breakfast food items

Clinical Evaluation of Angamardaprashamana Mahakashaya and Kativasti in the Management of Lumbar Spondylosis (Katigraha)

Lumbar spondylosis is a degenerative disease where degeneration occurs in lumbar vertebrae, intervertebral disc and in intervertebral joints, characterized by loss of hydration of disc followed by formation of osteophytes and transdiscal bridging. It involves the entire joint including the nearby muscles, underlying bone, ligament, disk and give rise to symptoms of Lumbar spondylosis. Katigraha is a Vataja nanatatmaja vyadhi mentioned by Sharangadhar and Shodala. As per Acharya Shodala, Vata situated in Asthi of Kati region, increased due to various Nidana (causes) and produce symptoms of vitiated Vata as Shula (pain), Pangutwa (disability) both the lower limbs known as Katigraha. Hence for treatment of lumbar spondylosis is correlated and treatment given according to Chikitsa modalities of Katigraha (Vatavyadhi Chikitsa). To evaluate the efficacy of Angamardaprashamana Mahakashaya and Kativasti in the management of lumbar spondylosis clinically a open, random, clinical trial is carried out on 100 patients in one group, as intervention Angamardaprashamana Mahakashaya Churna (powder form) is given orally and Kativasti (a type of sudation therapy) on lumbar region is given externally. Follow up taken in every 20th day upto 60 days. After treatment for statistical analysis of data paired t test is done and data shows highly significant result and shows remarkable changes in signs and symptoms. But its result of radiological changes are found not significant statistically. The relief % is analysis by using Oswestry Disability Index which shows 91% respond to treatment and 74% got major improvements. Thus, the study says that trial drug and therapy have capacity to improve lumbar spondylosis (Katigraha) significantl

Evaluate the Efficacy of Kshara Basti and Sunthi-Guduchi Churna in Amavata (Rheumatoid Arthritis)- A Clinical Study

Amavata is a Rasa Pradosaja Vikara with two major pathogenic factors Ama and Vata, which mainly affect Sandhi followed by Asthi and Majja. The symptoms of Amavata are identical to Rheumatoid Arthritis, a chronic inflammatory polyarthritis affecting multiple systems. The symptoms of Amavata are identical to rheumatism, which include rheumatoid arthritis and rheumatic fever. It is observed that rheumatism is an autoimmune disorder, which is among the collagen disorders having strong and significant parlance with Amavata. Various drug trials were already carried out on Amavata, yet there is a lacuna in the management of Amavata. Hence, in the present clinical study, 100 patients were selected for Open Random trial and applied Kshara basti followed by oral Sunthi- Guduchi churna for 2 month for the management of Amavata. In disease active stage of Amavata synovial stromal-immune cell interactions lead to reciprocal metabolic changes that again potentiate the inflammatory response. Here we can understand the metabolic and cellular pathology during active stage of disease. Hence, metabolic reprogramming could represent a new therapeutic strategy for patients with RA, where our Basti therapy followed by Rasayana must have a great role. For the study collected data was distributed according to age, sex and Prakruti, and a paired t-test was applied for the clinical assessment of the subjective and objective parameters of Kshara basti followed by Sunthi guduchi churna in Amavata management and it has shown significant reduction in the Sandhi shool according to VAS scale (t >23.42 at the 0.001% level), Sandhi sotha (t >24.35 , at the 0.001% level), Sandhi Stabdhata (t >20.58 at the 0.001% level), CDAI score (t >27.11 at the 0.001% level ) ANA score (t >53.23, at the 0.001% level), and for 1st 15 days ESR changes is not significant at t <1.00 but after completion of treatment significant results was observed. By analysing statistical data with paired t test it reveals that 58% had major improvement followed by 37% had minor improvement and 5% of patients who had no improvement

Abstracts of National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020

This book presents the abstracts of the papers presented to the Online National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020 (RDMPMC-2020) held on 26th and 27th August 2020 organized by the Department of Metallurgical and Materials Science in Association with the Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, India. Conference Title: National Conference on Research and Developments in Material Processing, Modelling and Characterization 2020Conference Acronym: RDMPMC-2020Conference Date: 26–27 August 2020Conference Location: Online (Virtual Mode)Conference Organizer: Department of Metallurgical and Materials Engineering, National Institute of Technology JamshedpurCo-organizer: Department of Production and Industrial Engineering, National Institute of Technology Jamshedpur, Jharkhand, IndiaConference Sponsor: TEQIP-