236 research outputs found

    Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex Determination

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    The boygirl (byg) mouse mutant reveals that MAP3K4-mediated signaling is necessary for normal SRY expression and testis specification in the developing mouse gonad

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

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    The production of tt‾ , W+bb‾ and W+cc‾ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓν , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of ttt\overline{t}, W+bbW+b\overline{b} and W+ccW+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays WνW\rightarrow\ell\nu, where \ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    Measurement of the B0s→μ+μ− Branching Fraction and Effective Lifetime and Search for B0→μ+μ− Decays

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    A search for the rare decays Bs0→μ+μ- and B0→μ+μ- is performed at the LHCb experiment using data collected in pp collisions corresponding to a total integrated luminosity of 4.4  fb-1. An excess of Bs0→μ+μ- decays is observed with a significance of 7.8 standard deviations, representing the first observation of this decay in a single experiment. The branching fraction is measured to be B(Bs0→μ+μ-)=(3.0±0.6-0.2+0.3)×10-9, where the first uncertainty is statistical and the second systematic. The first measurement of the Bs0→μ+μ- effective lifetime, τ(Bs0→μ+μ-)=2.04±0.44±0.05  ps, is reported. No significant excess of B0→μ+μ- decays is found, and a 95% confidence level upper limit, B(B0→μ+μ-)<3.4×10-10, is determined. All results are in agreement with the standard model expectations.A search for the rare decays Bs0μ+μB^0_s\to\mu^+\mu^- and B0μ+μB^0\to\mu^+\mu^- is performed at the LHCb experiment using data collected in pppp collisions corresponding to a total integrated luminosity of 4.4 fb1^{-1}. An excess of Bs0μ+μB^0_s\to\mu^+\mu^- decays is observed with a significance of 7.8 standard deviations, representing the first observation of this decay in a single experiment. The branching fraction is measured to be B(Bs0μ+μ)=(3.0±0.60.2+0.3)×109{\cal B}(B^0_s\to\mu^+\mu^-)=\left(3.0\pm 0.6^{+0.3}_{-0.2}\right)\times 10^{-9}, where the first uncertainty is statistical and the second systematic. The first measurement of the Bs0μ+μB^0_s\to\mu^+\mu^- effective lifetime, τ(Bs0μ+μ)=2.04±0.44±0.05\tau(B^0_s\to\mu^+\mu^-)=2.04\pm 0.44\pm 0.05 ps, is reported. No significant excess of B0μ+μB^0\to\mu^+\mu^- decays is found and a 95 % confidence level upper limit, B(B0μ+μ)<3.4×1010{\cal B}(B^0\to\mu^+\mu^-)<3.4\times 10^{-10}, is determined. All results are in agreement with the Standard Model expectations

    Study of the rare B-s(0) and B-0 decays into the pi(+) pi(-) mu(+) mu(-) final state

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    A search for the rare decays Bs0π+πμ+μB_s^0 \to \pi^+\pi^-\mu^+\mu^- and B0π+πμ+μB^0 \to \pi^+\pi^-\mu^+\mu^- is performed in a data set corresponding to an integrated luminosity of 3.0 fb1^{-1} collected by the LHCb detector in proton-proton collisions at centre-of-mass energies of 7 and 8 TeV. Decay candidates with pion pairs that have invariant mass in the range 0.5-1.3 GeV/c2c^2 and with muon pairs that do not originate from a resonance are considered. The first observation of the decay Bs0π+πμ+μB_s^0 \to \pi^+\pi^-\mu^+\mu^- and the first evidence of the decay B0π+πμ+μB^0 \to \pi^+\pi^-\mu^+\mu^- are obtained and the branching fractions are measured to be B(Bs0π+πμ+μ)=(8.6±1.5(stat)±0.7(syst)±0.7(norm))×108\mathcal{B}(B_s^0 \to \pi^+\pi^-\mu^+\mu^-)=(8.6\pm 1.5\,({\rm stat}) \pm 0.7\,({\rm syst})\pm 0.7\,({\rm norm}))\times 10^{-8} and B(B0π+πμ+μ)=(2.11±0.51(stat)±0.15(syst)±0.16(norm))×108\mathcal{B}(B^0 \to \pi^+\pi^-\mu^+\mu^-)=(2.11\pm 0.51\,({\rm stat}) \pm 0.15\,({\rm syst})\pm 0.16\,({\rm norm}) )\times 10^{-8}, where the third uncertainty is due to the branching fraction of the decay B0J/ψ(μ+μ)K(890)0(K+π)B^0\to J/\psi(\to \mu^+\mu^-)K^*(890)^0(\to K^+\pi^-), used as a normalisation.A search for the rare decays Bs0→π+π−μ+μ− and B0→π+π−μ+μ− is performed in a data set corresponding to an integrated luminosity of 3.0 fb−1 collected by the LHCb detector in proton–proton collisions at centre-of-mass energies of 7 and 8 TeV . Decay candidates with pion pairs that have invariant mass in the range 0.5–1.3 GeV/c2 and with muon pairs that do not originate from a resonance are considered. The first observation of the decay Bs0→π+π−μ+μ− and the first evidence of the decay B0→π+π−μ+μ− are obtained and the branching fractions, restricted to the dipion-mass range considered, are measured to be B(Bs0→π+π−μ+μ−)=(8.6±1.5 (stat)±0.7 (syst)±0.7(norm))×10−8 and B(B0→π+π−μ+μ−)=(2.11±0.51(stat)±0.15(syst)±0.16(norm))×10−8 , where the third uncertainty is due to the branching fraction of the decay B0→J/ψ(→μ+μ−)K⁎(892)0(→K+π−) , used as a normalisation.A search for the rare decays Bs0→π+π−μ+μ− and B0→π+π−μ+μ− is performed in a data set corresponding to an integrated luminosity of 3.0 fb−1 collected by the LHCb detector in proton–proton collisions at centre-of-mass energies of 7 and 8 TeV . Decay candidates with pion pairs that have invariant mass in the range 0.5–1.3 GeV/c2 and with muon pairs that do not originate from a resonance are considered. The first observation of the decay Bs0→π+π−μ+μ− and the first evidence of the decay B0→π+π−μ+μ− are obtained and the branching fractions, restricted to the dipion-mass range considered, are measured to be B(Bs0→π+π−μ+μ−)=(8.6±1.5 (stat)±0.7 (syst)±0.7(norm))×10−8 and B(B0→π+π−μ+μ−)=(2.11±0.51(stat)±0.15(syst)±0.16(norm))×10−8 , where the third uncertainty is due to the branching fraction of the decay B0→J/ψ(→μ+μ−)K⁎(892)0(→K+π−) , used as a normalisation.A search for the rare decays Bs0π+πμ+μB_s^0 \to \pi^+\pi^-\mu^+\mu^- and B0π+πμ+μB^0 \to \pi^+\pi^-\mu^+\mu^- is performed in a data set corresponding to an integrated luminosity of 3.0 fb1^{-1} collected by the LHCb detector in proton-proton collisions at centre-of-mass energies of 7 and 8 TeV. Decay candidates with pion pairs that have invariant mass in the range 0.5-1.3 GeV/c2c^2 and with muon pairs that do not originate from a resonance are considered. The first observation of the decay Bs0π+πμ+μB_s^0 \to \pi^+\pi^-\mu^+\mu^- and the first evidence of the decay B0π+πμ+μB^0 \to \pi^+\pi^-\mu^+\mu^- are obtained and the branching fractions, restricted to the dipion-mass range considered, are measured to be B(Bs0π+πμ+μ)=(8.6±1.5(stat)±0.7(syst)±0.7(norm))×108\mathcal{B}(B_s^0 \to \pi^+\pi^-\mu^+\mu^-)=(8.6\pm 1.5\,({\rm stat}) \pm 0.7\,({\rm syst})\pm 0.7\,({\rm norm}))\times 10^{-8} and B(B0π+πμ+μ)=(2.11±0.51(stat)±0.15(syst)±0.16(norm))×108\mathcal{B}(B^0 \to \pi^+\pi^-\mu^+\mu^-)=(2.11\pm 0.51\,({\rm stat}) \pm 0.15\,({\rm syst})\pm 0.16\,({\rm norm}) )\times 10^{-8}, where the third uncertainty is due to the branching fraction of the decay B0J/ψ(μ+μ)K(890)0(K+π)B^0\to J/\psi(\to \mu^+\mu^-)K^*(890)^0(\to K^+\pi^-), used as a normalisation

    Measurement of the (eta c)(1S) production cross-section in proton-proton collisions via the decay (eta c)(1S) -&gt; p(p)over-bar

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    Observation of the B0 → ρ0ρ0 decay from an amplitude analysis of B0 → (π+π−)(π+π−) decays

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    Proton–proton collision data recorded in 2011 and 2012 by the LHCb experiment, corresponding to an integrated luminosity of 3.0 fb−1 , are analysed to search for the charmless B0→ρ0ρ0 decay. More than 600 B0→(π+π−)(π+π−) signal decays are selected and used to perform an amplitude analysis, under the assumption of no CP violation in the decay, from which the B0→ρ0ρ0 decay is observed for the first time with 7.1 standard deviations significance. The fraction of B0→ρ0ρ0 decays yielding a longitudinally polarised final state is measured to be fL=0.745−0.058+0.048(stat)±0.034(syst) . The B0→ρ0ρ0 branching fraction, using the B0→ϕK⁎(892)0 decay as reference, is also reported as B(B0→ρ0ρ0)=(0.94±0.17(stat)±0.09(syst)±0.06(BF))×10−6

    Angular analysis of the B-0 -&gt; K*(0) e(+) e(-) decay in the low-q(2) region

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    An angular analysis of the B0K0e+eB^0 \rightarrow K^{*0} e^+ e^- decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 {\mbox{fb}^{-1}}, collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2q^2) interval between 0.002 and 1.120GeV2 ⁣/c4{\mathrm{\,Ge\kern -0.1em V^2\!/}c^4}. The angular observables FLF_{\mathrm{L}} and ATReA_{\mathrm{T}}^{\mathrm{Re}} which are related to the K0K^{*0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL=0.16±0.06±0.03F_{\mathrm{L}}= 0.16 \pm 0.06 \pm0.03 and ATRe=0.10±0.18±0.05A_{\mathrm{T}}^{\mathrm{Re}} = 0.10 \pm 0.18 \pm 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)A_{\mathrm{T}}^{(2)} and ATImA_{\mathrm{T}}^{\mathrm{Im}} which are sensitive to the photon polarisation in this q2q^2 range, are found to be AT(2)=0.23±0.23±0.05A_{\mathrm{T}}^{(2)} = -0.23 \pm 0.23 \pm 0.05 and ATIm=0.14±0.22±0.05A_{\mathrm{T}}^{\mathrm{Im}} =0.14 \pm 0.22 \pm 0.05. The results are consistent with Standard Model predictions.An angular analysis of the B0^{0} → K^{*}^{0} e+^{+} e^{−} decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 fb1^{−1}, collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2^{2}) interval between 0.002 and 1.120 GeV2^{2} /c4^{4}. The angular observables FL_{L} and ATRe_{T}^{Re} which are related to the K^{*}^{0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL_{L} = 0.16 ± 0.06 ± 0.03 and ATRe_{T}^{Re}  = 0.10 ± 0.18 ± 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)_{T}^{(2)} and ATIm_{T}^{Im} which are sensitive to the photon polarisation in this q2^{2} range, are found to be AT(2)_{T}^{(2)}  = − 0.23 ± 0.23 ± 0.05 and ATIm_{T}^{Im}  = 0.14 ± 0.22 ± 0.05. The results are consistent with Standard Model predictions.An angular analysis of the B0K0e+eB^0 \rightarrow K^{*0} e^+ e^- decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 {\mbox{fb}^{-1}}, collected by the LHCb experiment in pppp collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared (q2q^2) interval between 0.002 and 1.120GeV2 ⁣/c4{\mathrm{\,Ge\kern -0.1em V^2\!/}c^4}. The angular observables FLF_{\mathrm{L}} and ATReA_{\mathrm{T}}^{\mathrm{Re}} which are related to the K0K^{*0} polarisation and to the lepton forward-backward asymmetry, are measured to be FL=0.16±0.06±0.03F_{\mathrm{L}}= 0.16 \pm 0.06 \pm0.03 and ATRe=0.10±0.18±0.05A_{\mathrm{T}}^{\mathrm{Re}} = 0.10 \pm 0.18 \pm 0.05, where the first uncertainty is statistical and the second systematic. The angular observables AT(2)A_{\mathrm{T}}^{(2)} and ATImA_{\mathrm{T}}^{\mathrm{Im}} which are sensitive to the photon polarisation in this q2q^2 range, are found to be AT(2)=0.23±0.23±0.05A_{\mathrm{T}}^{(2)} = -0.23 \pm 0.23 \pm 0.05 and ATIm=0.14±0.22±0.05A_{\mathrm{T}}^{\mathrm{Im}} =0.14 \pm 0.22 \pm 0.05. The results are consistent with Standard Model predictions

    Search for the lepton flavour violating decay tau(-) -&gt; mu(-)mu(+)mu(-)

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    A search for the lepton flavour violating decay τμμ+μ\tau^-\rightarrow\mu^-\mu^+\mu^- is performed with the LHCb experiment. The data sample corresponds to an integrated luminosity of 1.0 fb1^{−1} of proton-proton collisions at a centre-of-mass energy of 7 TeV and 2.0 fb1^{−1} at 8 TeV. No evidence is found for a signal, and a limit is set at 90% confidence level on the branching fraction, B(τμμ+μ)<4.6×108\mathcal{B}(\tau^-\rightarrow\mu^-\mu^+\mu^-)<4.6\times10^{−8}.A search for the lepton flavour violating decay τ^{−} → μ^{−} μ+^{+} μ^{−} is performed with the LHCb experiment. The data sample corresponds to an integrated luminosity of 1.0 fb1^{−1} of proton-proton collisions at a centre-of-mass energy of 7 TeV and 2.0 fb1^{−1} at 8 TeV. No evidence is found for a signal, and a limit is set at 90% confidence level on the branching fraction, B(τμμ+μ)<4.6×108 \mathrm{\mathcal{B}}\left({\tau}^{-}\to {\mu}^{-}{\mu}^{+}{\mu}^{-}\right)<4.6\times {10}^{-8} .A search for the lepton flavour violating decay τμμ+μ\tau^-\to \mu^-\mu^+\mu^- is performed with the LHCb experiment. The data sample corresponds to an integrated luminosity of 1.0fb11.0\mathrm{\,fb}^{-1} of proton-proton collisions at a centre-of-mass energy of 7TeV7\mathrm{\,Te\kern -0.1em V} and 2.0fb12.0\mathrm{\,fb}^{-1} at 8TeV8\mathrm{\,Te\kern -0.1em V}. No evidence is found for a signal, and a limit is set at 90%90\% confidence level on the branching fraction, B(τμμ+μ)<4.6×108\mathcal{B}(\tau^-\to \mu^-\mu^+\mu^-) < 4.6 \times 10^{-8}

    Measurement of the CP-violating phase β\beta in B0J/ψπ+πB^0\rightarrow J/\psi \pi^+\pi^- decays and limits on penguin effects

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    Time-dependent CP violation is measured in the B0J/ψπ+πB^0\rightarrow J/\psi\pi^+\pi^- channel for each π+π\pi^+\pi^- resonant final state using data collected with an integrated luminosity of 3.0 fb1^{-1} in pppp collisions using the LHCb detector. The final state with the largest rate, J/ψρ0(770)J/\psi\rho^0(770), is used to measure the CP-violating angle 2βeff2\beta^{\rm eff} to be (41.7±9.66.3+2.8)(41.7\pm 9.6_{-6.3}^{+2.8})^{\circ}. This result can be used to limit the size of penguin amplitude contributions to CP violation measurements in, for example, Bs0J/ψϕB_s^0\rightarrow J/\psi\phi decays. Assuming approximate SU(3) flavour symmetry and neglecting higher order diagrams, the shift in the CP-violating phase ϕs\phi_s is limited to be within the interval [1.05-1.05^\circ, +1.181.18^\circ] at 95% confidence level. Changes to the limit due to SU(3) symmetry breaking effects are also discussed.Time-dependent CP violation is measured in the B(−−−)0→J/ψπ+π− channel for each π+π− resonant final state using data collected with an integrated luminosity of 3.0 fb −1 in pp collisions using the LHCb detector. The final state with the largest rate, J/ψρ0(770) , is used to measure the CP -violating angle 2βeff to be (41.7±9.6−6.3+2.8)° . This result can be used to limit the size of penguin amplitude contributions to CP violation measurements in, for example, B(−−−)s0→J/ψϕ decays. Assuming approximate SU(3) flavour symmetry and neglecting higher order diagrams, the shift in the CP -violating phase ϕs is limited to be within the interval [ −1.05°,+1.18° ] at 95% confidence level. Changes to the limit due to SU(3) symmetry breaking effects are also discussed.Time-dependent CP violation is measured in the B0J/ψπ+πB^0\rightarrow J/\psi\pi^+\pi^- channel for each π+π\pi^+\pi^- resonant final state using data collected with an integrated luminosity of 3.0 fb1^{-1} in pppp collisions using the LHCb detector. The final state with the largest rate, J/ψρ0(770)J/\psi\rho^0(770), is used to measure the CP-violating angle 2βeff2\beta^{\rm eff} to be (41.7±9.66.3+2.8)(41.7\pm 9.6_{-6.3}^{+2.8})^{\circ}. This result can be used to limit the size of penguin amplitude contributions to CP violation measurements in, for example, Bs0J/ψϕB_s^0\rightarrow J/\psi\phi decays. Assuming approximate SU(3) flavour symmetry and neglecting higher order diagrams, the shift in the CP-violating phase ϕs\phi_s is limited to be within the interval [1.05-1.05^\circ, +1.181.18^\circ] at 95% confidence level. Changes to the limit due to SU(3) symmetry breaking effects are also discussed.Time-dependent CP violation is measured in the B0→J/ψπ+π− channel for each π+π− resonant final state using data collected with an integrated luminosity of 3.0 fb −1 in pp collisions using the LHCb detector. The final state with the largest rate, J/ψρ0(770) , is used to measure the CP -violating angle 2βeff to be (41.7±9.6−6.3+2.8)° . This result can be used to limit the size of penguin amplitude contributions to CP violation measurements in, for example, Bs0→J/ψϕ decays. Assuming approximate SU(3) flavour symmetry and neglecting higher order diagrams, the shift in the CP -violating phase ϕs is limited to be within the interval [ −1.05°,+1.18° ] at 95% confidence level. Changes to the limit due to SU(3) symmetry breaking effects are also discussed
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