ANALISIS PERFORMANSI ALGORITMA QOS AWARE RESOURCE ALLOCATION UNTUK SISTEM KOMUNIKASI DEVICE TO DEVICE

Perkembangan teknologi Information and Communication Technology (ICT) yang semakin cepat membuat komunikasi kini bisa semakin lebih mudah, cepat, dan efektif diiringi dengan peningkatan jumlah pengguna seluler yang menyebabkan kepadatan trafik komunikasi dalam jaringan seluler juga semakin meningkat. Untuk mengatasi kepadatan trafik komunikasi dalam jaringan seluler tersebut, Tugas Akhir ini mengusulkan penggunaan sistem komunikasi Device-to Device (D2D). Komunikasi D2D ialah salah satu fitur dalam teknologi 5G yang membuat komunikasi dapat dilakukan langsung antara dua pengguna ponsel tanpa melalui evolved Node B (eNB) sehingga bisa menurunkan kepadatan trafik komunikasi, meningkatkan efisiensi energi, dan meningkatkan spectral efficiency. Namun, penggunaan sistem komunikasi ini mempunyai kelemahan yaitu timbulnya interferensi terhadap komunikasi telepon seluler dari Base Transceiver Station (BTS). Tugas Akhir ini melakukan pemodelan dan analisis menggunakan algoritma heuristik QoS-Aware Resource Allocation (QARA) untuk mengalokasi kanal dan pemilihan mode komunikasi agar dapat,meningkatkan throughput untuk pengguna komunikasi D2D, dan menjamin QoS dari pengguna komunikasi selular dan komunikasi D2D. Hasil akhir dari penelitian ini adalah Algoritma QoS Aware Resource Allocation (QARA) terbukti dapat digunakan untuk mengalokasikan kanal dan meminimalisasi interferensi. Hal ini ditandai dengan hasil analisis yang menghasilkan parameter performansi yang lebih baik pada hal sum rate, spectral efficiency, throughput,dan energy efficiency. . Kata Kunci: Device-to-Device (D2D), QoS-Aware Resource Allocation (QARA) algorithm, Signal to Interference plus Noise Ratio (SINR), Throughpu

Technological innovations in mental healthcare: harnessing the digital revolution

Digital technology has the potential to transform mental healthcare by connecting patients, services and health data in new ways. Digital online and mobile applications can offer patients greater access to information and services and enhance clinical management and early intervention through access to real-time patient data. However, substantial gaps exist in the evidence base underlying these technologies. Greater patient and clinician involvement is needed to evaluate digital technologies and ensure they target unmet needs, maintain public trust and improve clinical outcomes

Differential effects of polyphenols on proliferation and apoptosis in human myeloid and lymphoid leukemia cell lines.

Background: Mortality rates for leukemia are high despite considerable improvements in treatment. Since polyphenols exert pro-apoptotic effects in solid tumors, our study investigated the effects of polyphenols in haematological malignancies. The effect of eight polyphenols (quercetin, chrysin, apigenin, emodin, aloe-emodin, rhein, cis-stilbene and trans-stilbene) were studied on cell proliferation, cell cycle and apoptosis in four lymphoid and four myeloid leukemic cells lines, together with normal haematopoietic control cells. Methods: Cellular proliferation was measured by CellTiter-Glo® luminescent assay; and cell cycle arrest was assessed using flow cytometry of propidium iodide stained cells. Apoptosis was investigated by caspase-3 activity assay using flow cytometry and apoptotic morphology was confirmed by Hoescht 33342 staining. Results: Emodin, quercetin, and cis-stilbene were the most effective polyphenols at decreasing cell viability (IC50 values of 5-22 µM, 8-33 µM, and 25-85 µM respectively) and inducing apoptosis (AP50 values (the concentration which 50% of cells undergo apoptosis) of 2-27 µM, 19-50 µM, and 8-50 µM respectively). Generally, lymphoid cell lines were more sensitive to polyphenol treatment compared to myeloid cell lines, however the most resistant myeloid (KG-1a and K562) cell lines were still found to respond to emodin and quercetin treatment at low micromolar levels. Non-tumor cells were less sensitive to all polyphenols compared to the leukemia cells. Conclusions: These findings suggest that polyphenols have anti-tumor activity against leukemia cells with differential effects. Importantly, the differential sensitivity of emodin, quercetin, and cis-stilbene between leukemia and normal cells suggests that polyphenols are potential therapeutic agents for leukemia

Fabrication of low-cost, large-area prototype Si(Li) detectors for the GAPS experiment

A Si(Li) detector fabrication procedure has been developed with the aim of satisfying the unique requirements of the GAPS (General Antiparticle Spectrometer) experiment. Si(Li) detectors are particularly well-suited to the GAPS detection scheme, in which several planes of detectors act as the target to slow and capture an incoming antiparticle into an exotic atom, as well as the spectrometer and tracker to measure the resulting decay X-rays and annihilation products. These detectors must provide the absorption depth, energy resolution, tracking efficiency, and active area necessary for this technique, all within the significant temperature, power, and cost constraints of an Antarctic long-duration balloon flight. We report here on the fabrication and performance of prototype 2"-diameter, 1-1.25 mm-thick, single-strip Si(Li) detectors that provide the necessary X-ray energy resolution of $\sim$4 keV for a cost per unit area that is far below that of previously-acquired commercial detectors. This fabrication procedure is currently being optimized for the 4"-diameter, 2.5 mm-thick, multi-strip geometry that will be used for the GAPS flight detectors.Comment: Accepted for publication at Nuclear Instrumentation and Methods A, 12 pages, 11 figure

Effect of flow rate, flow direction, and silica addition on the performance of membrane and the corrosion behavior of Pt-Ru/C catalyst in PEMFC

a b s t r a c t In order to evaluate the performance of Proton Exchange Membrane Fuel Cell (PEMFC) with an active area of 25 cm 2 , several variables were studied (flow pattern, flow rate, degradation in the Pt-Ru/C catalyst). Polarization curves revealed that the electrochemical reaction on both sides of the fuel cell is under the effect of mass transfer and the values of the cell voltage, current density, and power density were inversely proportional with the increase of the hydrogen and oxygen flow rates for both flow patterns (counter current and cocurrent) and clear corrosion phenomenon was observed on the surface of the Pt-Ru/C catalyst before and after exposure to the hydrogen and oxygen. On the other hand and in order to increase the performance of Nafion membrane, SiO 2 particles were introduced to the Nafion polymeric matrix using sol-gel method to form composites. The surface morphology of the Nafion-SiO 2 composite membrane was investigated and compared with the existing commercial Nafion membrane. It was found that water uptake of the Nafion-silica composite membrane as a function of temperature is higher than that of the existing commercial Nafion membrane

Conference Rubric Development for STEM Librarians’ Publications

Librarians within the Engineering Libraries Division (ELD) annually publish conference papers for the American Society for Engineering Education (ASEE). The existing ASEE rubric was not sufficient for our members, so we developed a new rubric as a charged committee for this task. We briefly discuss the sparse literature in this area, focusing on the use of rubrics and the rationale behind them. Due to this lack of literature, our committee primarily utilized additional sources such as rubrics found from other professional organizations in STEM and library fields. Our rubric is designed to encourage substantive feedback and growth of authors during the process, while clarifying the expectations for submissions. This rubric consists of overall guidance and specific needs, with flexibility for the different research methods and applications expected (i.e. work-in-progress/completed research, quantitative/qualitative, etc.). We implemented this rubric successfully for the 2021 conference cycle, but will further refine it as needed, based on feedback following future conferences. With scarce literature on conference peer review, we hope by sharing our work, others may also consider and improve their organizations’ processes

Maintenance of intervention effects: long-term outcomes for participants in a group talk-therapy trial in the Democratic Republic of Congo

Abstract Background Despite the growth of psychotherapy trials in low- and middle-income countries, there have been limited follow-up studies of more than 2 years. This study follows up female sexual violence survivors approximately 6 years after completing a 12-session group cognitive processing therapy (CPT) program in the eastern Democratic Republic of Congo. Methods Baseline trial data were collected in December 2010 from 134 women in 7 study villages randomly allocated to CPT. Study women were over 18 years, reported personally experiencing or witnessing sexual violence, and reported elevated depression, anxiety and/or posttraumatic stress symptoms. Women were followed up (1) post-treatment (6-months after baseline); (2) 6 months later; (3) 12 months later; and (4) in March 2017 (6.3 years after baseline). At the long-term follow-up, 103 women (77%) in 6 of 7 CPT villages were re-assessed; one village was not visited due to ongoing insecurity. Results We found strong continued intervention effects; nearly all women maintained treatment impacts over the first two years; at long-term follow-up, approximately half continued to maintain low symptom scores. Relapse rates for probable PTSD and probable depression and anxiety were 20%. Conclusions This study extends prior research to show that treatment impacts can be maintained for several years despite experiences of ongoing trauma. The women described continuing to meet with the women in their therapy group and using the skills they learned in the psychotherapy, providing evidence of the potential for these programs to provide valuable social supports and skills that people use as they continue to face adversity

A practical Java tool for small-molecule compound appraisal

The increased use of small-molecule compound screening by new users from a variety of different academic backgrounds calls for adequate software to administer, appraise, analyse and exchange information obtained from screening experiments. While software and spreadsheet solutions exist, there is a need for software that can be easily deployed and is convenient to use.The Java application cApp addresses this need and aids in the handling and storage of information on small-molecule compounds. The software is intended for the appraisal of compounds with respect to their physico-chemical properties, analysis in relation to adherence to likeness rules as well as recognition of pan-assay interference components and cross-linking with identical entries in the PubChem Compound Database. Results are displayed in a tabular form in a graphical interface, but can also be written in an HTML or PDF format. The output of data in ASCII format allows for further processing of data using other suitable programs. Other features include similarity searches against user-provided compound libraries and the PubChem Compound Database, as well as compound clustering based on a MaxMin algorithm.cApp is a personal database solution for small-molecule compounds which can handle all major chemical formats. Being a standalone software, it has no other dependency than the Java virtual machine and is thus conveniently deployed. It streamlines the analysis of molecules with respect to physico-chemical properties and drug discovery criteria; cApp is distributed under the GNU Affero General Public License version 3 and available from http://www.structuralchemistry.org/pcsb/. To download cApp, users will be asked for their name, institution and email address. A detailed manual can also be downloaded from this site, and online tutorials are available at http://www.structuralchemistry.org/pcsb/capp.php