159 research outputs found
Determinants of Employee Satisfaction: a case study of Banking Sector in Lahore, Pakistan
The contributing role of financial institutions towards stabilization and growth of an economy cannot be overlooked. Employees play a pivotal role in achieving organizational goals. Gaining employee satisfaction and commitment is a gnawing concern facing banking industry of Pakistan. This paper aims to investigate the impact of factors such as work ā family balance, perceived job security and person-environment fit on employee satisfaction in the banking sector of Lahore, Pakistan. Using systematic random sampling technique, a sample of 252 employees from various banks was surveyed using a structured and standardized questionnaire. Correlation and regression techniques were applied to analyze the data. The results supported the study hypotheses, revealing that work-family balance, perceived job security and person-environment fit had impact of employee satisfaction in the banking sector. Keywords: Employee Satisfaction, Work-Family Balance, Perceived Job Security, Person-Environment Fi
Determinants of Employee Satisfaction: A Case Study of Banking Sector in Lahore, Pakistan
The contributing role of financial institutions towards stabilization and growth of an economy cannot be overlooked. Employees play a pivotal role in achieving organizational goals. Gaining employee satisfaction and commitment is a gnawing concern facing banking industry of Pakistan. This paper aims to investigate the impact of factors such as work ā family balance, perceived job security and Person-Environment (P.E) Fit on employee satisfaction in the banking sector of Lahore, Pakistan. Using systematic random sampling technique, a sample of 252 employees from various banks was surveyed using a structured and standardized questionnaire. Correlation and regression techniques were applied to analyze the data. The results supported the study hypotheses, revealing that work-family balance, perceived job security and person-environment fit had impact of employee satisfaction in the banking sector. Keywords: Employee Satisfaction, Work-Family Balance, Perceived Job Security, Person-Environment Fi
DETERMINANTS OF ORGANIC FOOD PURCHASE BEHAVIOR: A MEDIATION ANALYSIS
The adoption of sustainable practices is an imperative and urgent need for economies. The food manufacturing processes and the consumption patterns have an impact on the individuals and the atmosphere. This study has been conducted with the aim to understand the determinants of organic food purchase behavior. For that purpose, this study hypothesized the mediation effects of attitudes towards buying organic food between organic food purchase behavior and four consumers’ personal factors, green marketing practices and price barriers. The research was carried out in the developing economy of Islamic Republic of Pakistan. Convenience Sampling was used as the sampling technique. For this research, the respondents were 260 consumers of organic foods from the city of Lahore, Pakistan. The technique applied on this study was Process Hayes. The results of the data suggested that attitude towards buying organic food has positive significant mediations between organic food purchase behavior and all of the dependent variables. Keywords: Environmental Concerns; Organic Food Purchase Behavior; Green Marketinghttps://doi.org/10.56249/ijbr.03.01.2
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BRAF V600E-Positive Multisite Langerhans Cell Histiocytosis in a Preterm Neonate
Hemorrhagic pustules with a āblueberry muffinā appearance accompanied by respiratory failure in a neonate present a challenging differential diagnosis that includes infections and neoplasms. We present a case of multiorgan, multisite Langerhans cell histiocytosis (LCH), positive for the oncogenic BRAF V600E mutation, in a preterm neonate. Infants with LCH pose a diagnostic challenge due to their heterogeneous presentations. This case is unusual in that the newborn presented with severe multiorgan involvement. Due to the rare incidence, wide spectrum of clinical manifestations, and high mortality rate, clinicians must maintain a high index of suspicion for LCH
Results from the centers for disease control and prevention's predict the 2013-2014 Influenza Season Challenge
Background: Early insights into the timing of the start, peak, and intensity of the influenza season could be useful in planning influenza prevention and control activities. To encourage development and innovation in influenza forecasting, the Centers for Disease Control and Prevention (CDC) organized a challenge to predict the 2013-14 Unites States influenza season. Methods: Challenge contestants were asked to forecast the start, peak, and intensity of the 2013-2014 influenza season at the national level and at any or all Health and Human Services (HHS) region level(s). The challenge ran from December 1, 2013-March 27, 2014; contestants were required to submit 9 biweekly forecasts at the national level to be eligible. The selection of the winner was based on expert evaluation of the methodology used to make the prediction and the accuracy of the prediction as judged against the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet). Results: Nine teams submitted 13 forecasts for all required milestones. The first forecast was due on December 2, 2013; 3/13 forecasts received correctly predicted the start of the influenza season within one week, 1/13 predicted the peak within 1 week, 3/13 predicted the peak ILINet percentage within 1 %, and 4/13 predicted the season duration within 1 week. For the prediction due on December 19, 2013, the number of forecasts that correctly forecasted the peak week increased to 2/13, the peak percentage to 6/13, and the duration of the season to 6/13. As the season progressed, the forecasts became more stable and were closer to the season milestones. Conclusion: Forecasting has become technically feasible, but further efforts are needed to improve forecast accuracy so that policy makers can reliably use these predictions. CDC and challenge contestants plan to build upon the methods developed during this contest to improve the accuracy of influenza forecasts. Ā© 2016 The Author(s)
Graphene Based Functional Hybrids: Design and Technological Applications
Because of the versatile chemical, physical, and electrical properties, graphene as well as its nanocomposites are regarded as the backbone of engineering and scientific innovation. Different physical and chemical methods are used to create sustainable carbon materials. Furthermore, fabrication methods are employed in order to produce the composites, which are of constituents with desirable properties. Because of their biocompatibility, graphene nanomaterials have enormous potential for improving biology and drug delivery. The proposed chapter provides a variety of fabrication methods for sustainable graphene composites and highlights various applications of graphene. Furthermore, graphene nanocomposites are promising multifunctional materials with improved tensile strength and elastic modulus. Despite some challenges and the fact that carbon nanotube/polymer composites are sometimes better in some specific performance, graphene nanocomposites may have a wide range of potential applications due to their outstanding properties and the low cost of graphene. Because these graphene composites have a controllable porous structure, a large surface area, high conductivity, high temperature stability, excellent anti-corrosion properties, and composite compatibility, they can be used in energy storage as electrocatalysts, electro-conductive additives, intercalation hosts, and an ideal substrate for active materials. Meanwhile, the chapter summaries the graphene nanocomposites requirements for technological innovation and scientific applied research
Profiling estrogen, progesterone, and androgen receptors in colorectal cancer in relation to gender, menopausal status, clinical stage, and tumour sidedness
BackgroundAlthough estrogen (ERĪ±/ERĪ²), progesterone (PGR), and androgen (AR) receptors are pathologically altered in colorectal cancer (CRC), their simultaneous expression within the same cohort of patients was not previously measured.MethodsERĪ±/ERĪ²/PGR/AR proteins were measured in archived paired normal and malignant colon specimens (n =120 patients) by immunohistochemistry, and results were analyzed by gender, age (ā¤50 vs. ā„60 years), clinical stages (early-stage I/II vs. late-stage III/IV), and anatomical location (right; RSCs vs. left; LSCs). Effects of 17Ī²-estradiol (E2), progesterone (P4), and testosterone alone or combined with the specific blockers of ERĪ± (MPP dihydrochloride), ERĪ² (PHTPP), PGR (mifepristone), and AR (bicalutamide) on cell cycle and apoptosis were also measured in the SW480 male and HT29 female CRC cell lines. ResultsERĪ± and AR proteins increased, whilst ERĪ² and PGR declined markedly in malignant specimens. Moreover, male neoplastic tissues showed highest AR expression, whilst ERĪ² and PGR weakest alongside ERĪ± strongest expression was seen in cancerous tissues from women aged ā„60 years. Late-stage neoplasms also revealed maximal alterations in the expression of sex steroid receptors. By tumor location, LSCs disclosed significant elevations in ERĪ± with marked declines in PGR compared with RSCs, and ERĪ± strongest alongside PGR weakest expression was detected in advanced LSCs from women aged ā„60 years. Late-stage LSCs from females aged ā„60 years also showed weakest ERĪ² and strongest AR expression. In contrast, male RSC and LSC tissues exhibited equal ERĪ² and AR expression in all clinical stages. ERĪ± and AR proteins also correlated positively, whereas ERĪ² and PGR inversely, with tumor characteristics. Concomitantly, E2 and P4 monotherapies triggered cell cycle arrest and apoptosis in the SW480 and HT29 cells, and while pre-treatment with ERĪ±-blocker enhanced the effects of E2, ERĪ²-blocker and PGR-blocker suppressed the E2 and P4 anti-cancer actions, respectively. In contrast, treatment with the AR-blocker induced apoptosis, whilst co-treatment with testosterone hindered the effects. ConclusionsThis study advocates that protein expression of sex steroid receptors in malignant tissues could represent prognostic markers, as well as hormonal therapy could provide an alternative strategy against CRC, and their efficacies could be dependent on gender, clinical stage, and tumor location
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