Luteinizing hormone concentrations in healthy horses and horses with trigeminal-mediated headshaking over an 8-hour period.

BackgroundTrigeminal-mediated headshaking results from a low threshold for firing of the trigeminal nerve. A seasonal component has been implicated in onset of clinical signs, which occur during the spring and summer months. Geldings are overrepresented in the affected population and hormonal differences as compared to a healthy control population of geldings might contribute to headshaking.Objective/hypothesisTo assess concentrations of luteinizing hormone (LH) over an 8-hour period in gelded healthy controls and horses affected with headshaking. Our hypothesis was that geldings with seasonal headshaking would have higher concentrations of LH over an 8-hour period compared to control horses during the summer when affected horses manifested headshaking.AnimalsTwelve geldings (6 controls and 6 affected).MethodsProspective controlled trial. Blood samples were drawn every 15 minutes over an 8-hour time period during summer from all horses to measure circulating LH concentrations by using a radioimmunoassay for equine LH. All affected horses were actively affected by headshaking at the time of sample collection.ResultsNo statistically significant differences in LH concentrations were found throughout the study period in headshakers as compared to control horses. Time had no significant effect, but a slight decrease in LH concentrations was observed for all horses. The main limitation of the study was the low number of horses.Conclusions and clinical importanceHorses affected with headshaking did not have significant differences in circulating LH during the late summer as compared to control horses

Search for direct production of charginos, neutralinos and sleptons in final states with two leptons and missing transverse momentum in pp collisions at √s = 8TeV with the ATLAS detector

Searches for the electroweak production of charginos, neutralinos and sleptons in final states characterized by the presence of two leptons (electrons and muons) and missing transverse momentum are performed using 20.3 fb−1 of proton-proton collision data at s√ = 8 TeV recorded with the ATLAS experiment at the Large Hadron Collider. No significant excess beyond Standard Model expectations is observed. Limits are set on the masses of the lightest chargino, next-to-lightest neutralino and sleptons for different lightest-neutralino mass hypotheses in simplified models. Results are also interpreted in various scenarios of the phenomenological Minimal Supersymmetric Standard Model

Measurement of the production of a W boson in association with a charm quark in pp collisions at √s = 7 TeV with the ATLAS detector

The production of a W boson in association with a single charm quark is studied using 4.6 fb−1 of pp collision data at s√ = 7 TeV collected with the ATLAS detector at the Large Hadron Collider. In events in which a W boson decays to an electron or muon, the charm quark is tagged either by its semileptonic decay to a muon or by the presence of a charmed meson. The integrated and differential cross sections as a function of the pseudorapidity of the lepton from the W-boson decay are measured. Results are compared to the predictions of next-to-leading-order QCD calculations obtained from various parton distribution function parameterisations. The ratio of the strange-to-down sea-quark distributions is determined to be 0.96+0.26−0.30 at Q 2 = 1.9 GeV2, which supports the hypothesis of an SU(3)-symmetric composition of the light-quark sea. Additionally, the cross-section ratio σ(W + +c¯¯)/σ(W − + c) is compared to the predictions obtained using parton distribution function parameterisations with different assumptions about the s−s¯¯¯ quark asymmetry

Seismic Hazard and Ground Motion Characterization at the Itoiz Dam (Northern Spain).

This paper presents a new hazard-consistent ground motion characterization of the Itoiz dam site, located in Northern Spain. Firstly, we propose a methodology with different approximation levels to the expected ground motion at the dam site. Secondly, we apply this methodology taking into account the particular characteristics of the site and of the dam. Hazard calculations were performed following the Probabilistic Seismic Hazard Assessment method using a logic tree, which accounts for different seismic source zonings and different ground-motion attenuation relationships. The study was done in terms of peak ground acceleration and several spectral accelerations of periods coinciding with the fundamental vibration periods of the dam. In order to estimate these ground motions we consider two different dam conditions: when the dam is empty (T = 0.1 s) and when it is filled with water to its maximum capacity (T = 0.22 s). Additionally, seismic hazard analysis is done for two return periods: 975 years, related to the project earthquake, and 4,975 years, identified with an extreme event. Soil conditions were also taken into account at the site of the dam. Through the proposed methodology we deal with different forms of characterizing ground motion at the study site. In a first step, we obtain the uniform hazard response spectra for the two return periods. In a second step, a disaggregation analysis is done in order to obtain the controlling earthquakes that can affect the dam. Subsequently, we characterize the ground motion at the dam site in terms of specific response spectra for target motions defined by the expected values SA (T) of T = 0.1 and 0.22 s for the return periods of 975 and 4,975 years, respectively. Finally, synthetic acceleration time histories for earthquake events matching the controlling parameters are generated using the discrete wave-number method and subsequently analyzed. Because of the short relative distances between the controlling earthquakes and the dam site we considered finite sources in these computations. We conclude that directivity effects should be taken into account as an important variable in this kind of studies for ground motion characteristics

Caracterización del movimiento fuerte en el emplazamiento de la presa de Itoiz

Se presenta en este trabajo una nueva caracterización del movimiento del suelo en la presa de Itoiz, consistente con la peligrosidad sísmica del emplazamiento. En primer lugar, proponemos una metodología con tres niveles de aproximación al movimiento esperado, que es después aplicada considerando las características particulares de la presa y su emplazamiento. Los cálculos de peligrosidad se realizan siguiendo la línea metodológica conocida como PSHA, con un método probabilista zonificado y formulando un árbol lógico que combina diferentes zonificaciones sísmicas y modelos de movimiento fuerte. La peligrosidad se representa en términos de la aceleración pico PGA y de las aceleraciones espectrales para periodos coincidentes con los de vibración de la presa, considerando dos estados de la misma correspondientes a presa vacía (T=0.1s) y presa con capacidad máxima de llenado (T=0.22 s). Se caracterizan los correspondientes movimientos para dos periodos de retorno, 975 años y 4975 años, asociados al sismo de proyecto y al sismo extremo, respectivamente. El efecto de sitio en el emplazamiento de la presa también fue tenido en cuenta. La metodología propuesta conduce a caracterizar el movimiento con tres niveles de detalle. En una primera etapa se obtienen los espectros de respuesta uniforme (UHS) para los dos niveles de movimiento referidos. Seguidamente se desarrolla un análisis de desagregación para obtener los sismos de control que previsiblemente pueden afectar mas a la presa. Estos se identifican como los que más contribuyen a los movimientos objeto dados por las aceleraciones espectrales de los dos periodos característicos, SA (0,1 s) y SA (0.22 s) y para los dos periodos de retorno de 975 y 4975 años asociados a lo sismos de proyecto y extremo. De ahí se obtienen los espectros de respuesta específicos para las cuatro combinaciones resultantes. Finalmente, se realiza una simulación del movimiento en el dominio del tiempo, obteniendo acelerogramas sintéticos mediante el método de número de onda discreto. Las simulaciones se realizaron considerando fuentes finitas en diferentes posiciones y evaluando el efecto de la directividad en las posibles fuentes consideradas. Se concluye destacando la importancia del efecto de directividad, en la caracterización del emplazamiento de la presa