Programación metabólica de la eficiencia alimentaria en corderos: efecto de la restricción de alimento en la etapa de lactancia y mecanismos moleculares implicados = Metabolic programming of lamb feed efficiency: effect of feed restriction during the suckling period and molecular mechanisms involved

228 p.El objetivo general de este trabajo electoral es estudiar el efecto de una restricción moderada de alimento durante la lactancia sobre la eficiencia alimentaria de corderos en la etapa posdestete (cebo y recría), así como los mecanismos moleculares subyacentes que intervienen en el proceso

Discovering HIV related information by means of association rules and machine learning

Acquired immunodeficiency syndrome (AIDS) is still one of the main health problems worldwide. It is therefore essential to keep making progress in improving the prognosis and quality of life of affected patients. One way to advance along this pathway is to uncover connections between other disorders associated with HIV/AIDS-so that they can be anticipated and possibly mitigated. We propose to achieve this by using Association Rules (ARs). They allow us to represent the dependencies between a number of diseases and other specific diseases. However, classical techniques systematically generate every AR meeting some minimal conditions on data frequency, hence generating a vast amount of uninteresting ARs, which need to be filtered out. The lack of manually annotated ARs has favored unsupervised filtering, even though they produce limited results. In this paper, we propose a semi-supervised system, able to identify relevant ARs among HIV-related diseases with a minimal amount of annotated training data. Our system has been able to extract a good number of relationships between HIV-related diseases that have been previously detected in the literature but are scattered and are often little known. Furthermore, a number of plausible new relationships have shown up which deserve further investigation by qualified medical experts