Preliminary EoS for core-collapse supernova simulations with the QMC model

In this work we present the preliminary results of a complete equation of state (EoS) for core-collapse supernova simulations. We treat uniform matter made of nucleons using the the quark-meson coupling (QMC) model. We show a table with a variety of thermodynamic quantities, which covers the proton fraction range $Y_{p}=0-0.65$ with the linear grid spacing $\Delta Y_{p}=0.01$ ($66$ points) and the density range $\rho_{B}=10^{14}-10^{16}$g.cm$^{-3}$ with the logarithmic grid spacing $\Delta log_{10}(\rho_{B}/[$g.cm$^{-3}])=0.1$ ($21$ points). This preliminary study is performed at zero temperature and our results are compared with the widely used EoS already available in the literature

Parameterized Complexity of Equitable Coloring

A graph on $n$ vertices is equitably $k$-colorable if it is $k$-colorable and every color is used either $\left\lfloor n/k \right\rfloor$ or $\left\lceil n/k \right\rceil$ times. Such a problem appears to be considerably harder than vertex coloring, being $\mathsf{NP\text{-}Complete}$ even for cographs and interval graphs. In this work, we prove that it is $\mathsf{W[1]\text{-}Hard}$ for block graphs and for disjoint union of split graphs when parameterized by the number of colors; and $\mathsf{W[1]\text{-}Hard}$ for $K_{1,4}$-free interval graphs when parameterized by treewidth, number of colors and maximum degree, generalizing a result by Fellows et al. (2014) through a much simpler reduction. Using a previous result due to Dominique de Werra (1985), we establish a dichotomy for the complexity of equitable coloring of chordal graphs based on the size of the largest induced star. Finally, we show that \textsc{equitable coloring} is $\mathsf{FPT}$ when parameterized by the treewidth of the complement graph

Isospin Constraints on the Parametric Coupling Model for Nuclear Matter

We make use of isospin constraints to study the parametric coupling model and the properties of asymmetric nuclear matter. Besides the usual constraints for nuclear matter - effective nucleon mass and the incompressibility at saturation density - and the neutron star constraints - maximum mass and radius - we have studied the properties related with the symmetry energy. These properties have constrained to a small range the parameters of the model. We have applied our results to study the thermodynamic instabilities in the liquid-gas phase transition as well as the neutron star configurations.Comment: 11 pages, 10 figure

Demarcation of local neighborhoods to study relations between contextual factors and health

<p>Abstract</p> <p>Background</p> <p>Several studies have highlighted the importance of collective social factors for population health. One of the major challenges is an adequate definition of the spatial units of analysis which present properties potentially related to the target outcomes. Political and administrative divisions of urban areas are the most commonly used definition, although they suffer limitations in their ability to fully express the neighborhoods as social and spatial units.</p> <p>Objective</p> <p>This study presents a proposal for defining the boundaries of local neighborhoods in Rio de Janeiro city. Local neighborhoods are constructed by means of aggregation of contiguous census tracts which are homogeneous regarding socioeconomic indicators.</p> <p>Methodology</p> <p>Local neighborhoods were created using the SKATER method (TerraView software). Criteria used for socioeconomic homogeneity were based on four census tract indicators (income, education, persons per household, and percentage of population in the 0-4-year age bracket) considering a minimum population of 5,000 people living in each local neighborhood. The process took into account the geographic boundaries between administrative neighborhoods (a political-administrative division larger than a local neighborhood, but smaller than a borough) and natural geographic barriers.</p> <p>Results</p> <p>The original 8,145 census tracts were collapsed into 794 local neighborhoods, distributed along 158 administrative neighborhoods. Local neighborhoods contained a mean of 10 census tracts, and there were an average of five local neighborhoods per administrative neighborhood.</p> <p>The local neighborhood units demarcated in this study are less socioeconomically heterogeneous than the administrative neighborhoods and provide a means for decreasing the well-known statistical variability of indicators based on census tracts. The local neighborhoods were able to distinguish between different areas within administrative neighborhoods, particularly in relation to squatter settlements.</p> <p>Conclusion</p> <p>Although the literature on neighborhood and health is increasing, little attention has been paid to criteria for demarcating neighborhoods. The proposed method is well-structured, available in open-access software, and easily reproducible, so we expect that new experiments will be conducted to evaluate its potential use in other settings. The method is thus a potentially important contribution to research on intra-urban differentials, particularly concerning contextual factors and their implications for different health outcomes.</p

DNA and chromosomal damage in Senegalese sole (Solea senegalensis) as side effects of ozone-based water treatment - contribution to optimization of fish-farming practices

The progressive growth of aquaculture implicates a dependence on large water amounts, which are submitted to disinfection processes, namely ozonation. Considering the importance of genomic integrity, it is critical to improve the knowledge on ozone-related genotoxic hazard to organisms reared in recirculating aquaculture systems (RAS) applying ozonation. Therefore, genetic damage induced by ozone exposure in the Senegalese sole (Solea senegalensis) was assessed, combining the comet and the erythrocytic nuclear abnormalities (ENA) assays, reflecting different damage levels, i.e. DNA and chromosomal damage, respectively. Fish were subjected to a daily 6-h ozone (0.15 mg L-1) exposure, repeated for 3 consecutive days, simulating a short-term event of overozonation. To assess the temporal impact of the previous event, the progression of damage was evaluated 7 days later, following transference to ozone-free water or to 0.07 mg L-1 ozone, a routinely adopted level in RAS. Both endpoints pointed to the ozone genotoxic potential, displaying DNA oxidation as a possible mechanism of damage. Overall, the present findings pointed out the genotoxic hazard of ozone to fish, highlighting the importance of these types of studies and contributing to improve aquaculture practices, namely in RAS systems. These early genotoxic signals may be a prelude to negative repercussions on fish health, which may affect the aquaculture productivity. The present findings recommend precautions in relation to accidental or intentional overozonation in fish-farming, even when short-term events are considered. The strategies to mitigate the impact of ozonation in S. senegalensis may include a dietary extra supplementation of antioxidants (regularly, or punctually in cases of overozonation).publishe

Papel da imunofenotipagem por citometria de fluxo no diagnóstico diferencial das pancitopenias e das linfocitoses

A imunofenotipagem por citometria de fluxo (CMF) é atualmente uma ferramenta indispensável para o diagnóstico hematopatológico. Nos últimos anos muitos progressos foram alcançados em instrumentação, novos anticorpos e fluorocromos e programas de análise. Consequentemente, houve um grande avanço no conhecimento da patogênese das neoplasias hematológicas e novos marcadores diagnósticos e prognósticos foram descritos. Revisamos aqui a contribuição destas novas técnicas no diagnóstico diferencial de pacientes com bi- ou pancitopenia e linfocitose. São apresentados os achados mais frequentes e as dificuldades na interpretação dos resultados. Além disto, a importância do uso concomitante de um conjunto de outras técnicas diagnósticas é demonstrada