jmodeltest.org: selection of nucleotide substitution models on the cloud

This is a pre-copyedited, author-produced version of an article accepted for publication in Bioinformatics following peer review. The version of record Jose Manuel Santorum, Diego Darriba, Guillermo L. Taboada, David Posada; jmodeltest.org: selection of nucleotide substitution models on the cloud, Bioinformatics, Volume 30, Issue 9, 1 May 2014, Pages 1310–1311, https://doi.org/10.1093/bioinformatics/btu032[Abstract] The selection of models of nucleotide substitution is one of the major steps of modern phylogenetic analysis. Different tools exist to accomplish this task, among which jModelTest 2 (jMT2) is one of the most popular. Still, to deal with large DNA alignments with hundreds or thousands of loci, users of jMT2 need to have access to High Performance Computing clusters, including installation and configuration capabilities, conditions not always met. Here we present jmodeltest.org, a novel web server for the transparent execution of jMT2 across different platforms and for a wide range of users. Its main benefit is straightforward execution, avoiding any configuration/execution issues, and reducing significantly in most cases the time required to complete the analysis. Availability and implementation:jmodeltest.org is accessible using modern browsers, such as Firefox, Chrome, Opera, Safari and IE from http://jmodeltest.org. User registration is not mandatory, but users wanting to have additional functionalities, like access to previous analyses, have the possibility of opening a user account.European Research Council; 2007-Stg 203161- PHYGENOMMinisterio de Ciencia e Innovación; TIN2010-1673