Of less known literary work of Ivan Golub before the 1990s

Kronologija objavljivanja književnih djela svećenika, književnika i znanstvenika Ivana Goluba sugerira da se, osim rijetkih izuzetaka iz ranijeg razdoblja, književnim stvaralaštvom intenzivnije počeo baviti tek 1990-ih godina. No, kada u obzir uzmemo do danas uglavnom nepoznata njegova djela koja su nastala znatno prije, ali su objavljena tek 1990-ih godina, i to vjerojatno prije svega zahvaljujući slomu komunističkog društveno-političkog poretka koji je do tada proskribirao književnost kršćanskog nadahnuća, postaje jasno da se Golub književnim stvaralaštvom u kontinuitetu i otprilike jednakim intenzitetom ustvari bavio još od 1970-ih pa sve do danas.The order in which literary works by Ivan Golub, a Croatian priest, author and scientist, were published suggests, with some rare exceptions early on, that he started writing intensely only after the 1990s. However, we should take into consideration his works that are mostly unknown today and were created well before, but published only in the 1990s. That is probably because of the collapse of the communist socio-political order, which had prohibited literature of Christian inspiration up until then. It then becomes clear that Golub has been writing with the same intensity ever since the 1970s and to this day

Hydrolytic stability in hemilabile metal–organic frameworks

Highly porous metal–organic frameworks (MOFs), which have undergone exciting developments over the past few decades, show promise for a wide range of applications. However, many studies indicate that they suffer from significant stability issues, especially with respect to their interactions with water, which severely limits their practical potential. Here we demonstrate how the presence of ‘sacrificial’ bonds in the coordination environment of its metal centres (referred to as hemilability) endows a dehydrated copper-based MOF with good hydrolytic stability. On exposure to water, in contrast to the indiscriminate breaking of coordination bonds that typically results in structure degradation, it is non-structural weak interactions between the MOF’s copper paddlewheel clusters that are broken and the framework recovers its as-synthesized, hydrated structure. This MOF retained its structural integrity even after contact with water for one year, whereas HKUST-1, a compositionally similar material that lacks these sacrificial bonds, loses its crystallinity in less than a day under the same conditions

Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study.

Background: Acute illness, existing co-morbidities and surgical stress response can all contribute to postoperative acute kidney injury (AKI) in patients undergoing major gastrointestinal surgery. The aim of this study was prospectively to develop a pragmatic prognostic model to stratify patients according to risk of developing AKI after major gastrointestinal surgery. Methods: This prospective multicentre cohort study included consecutive adults undergoing elective or emergency gastrointestinal resection, liver resection or stoma reversal in 2-week blocks over a continuous 3-month period. The primary outcome was the rate of AKI within 7 days of surgery. Bootstrap stability was used to select clinically plausible risk factors into the model. Internal model validation was carried out by bootstrap validation. Results: A total of 4544 patients were included across 173 centres in the UK and Ireland. The overall rate of AKI was 14·2 per cent (646 of 4544) and the 30-day mortality rate was 1·8 per cent (84 of 4544). Stage 1 AKI was significantly associated with 30-day mortality (unadjusted odds ratio 7·61, 95 per cent c.i. 4·49 to 12·90; P < 0·001), with increasing odds of death with each AKI stage. Six variables were selected for inclusion in the prognostic model: age, sex, ASA grade, preoperative estimated glomerular filtration rate, planned open surgery and preoperative use of either an angiotensin-converting enzyme inhibitor or an angiotensin receptor blocker. Internal validation demonstrated good model discrimination (c-statistic 0·65). Discussion: Following major gastrointestinal surgery, AKI occurred in one in seven patients. This preoperative prognostic model identified patients at high risk of postoperative AKI. Validation in an independent data set is required to ensure generalizability