MUSALI - A DIVINE HERB WITH ITS MEDICINAL USES

Musali is one of the reputed drug mentioned in the ancient books of Ayurveda and Siddha. It is good for all round development of health Musali is called as Divine Medicine for its medicinal qualities. Musali is also called Talamuli, Suvaha, Talamulika, Deerghakandika, Talapatri in Ayurveda. Acharya Charaka describe Musali in the treatment of respiratory disorders. Sushruta mentioned it in the treatment of Urolithiasis and in the treatment of Chronic obstructive pulmonary disease. In Rajnighantu it has been described as sweet, cooling, mucilaginous, increase Kapha and reduces Pitta daha (burning sensation), act as stimulant, gives strength. It is one of the important Rasayana drugs of Ayurvedic Materia Medica for vigour and vitality. It is an important ingredient of many Ayurvedic preparation and is considered to have aphrodisiac, immunostimulant, hepatoprotective, antioxidant, anticancer and antidiabetic activities. Hence the present study include its general introduction its type, Ayuredic literature, pharmacological activities and variable uses of Musali in several disease.&nbsp

A R&D productivity model to achieve self-sustainability for public funded/CSIR R&D laboratories, India

Purpose – The paper develops a model for enhancing R&D productivity for Indian public funded laboratories. The paper utilizes the productivity data of five Council of Scientific and Industrial Research (CSIR) laboratories for analysis and to form the constructs of the model. Design/methodology/approach – The weighted average method was employed for analyzing the rankings of survey respondents pertaining to the significant measures enhancing R&D involvement of researchers and significant non-R&D jobs. The authors have proposed a model of productivity. Various individual, organizational and environmental constructs related to the researchers working in the CSIR laboratories have been outlined that can enhance R&D productivity of researchers in Indian R&D laboratories. Partial Least Squares-Structural Equation Modeling (PLS-SEM) was used to find the predictability of the productivity model. Findings – The organizational factors have a crucial role in enhancing the R&D outputs of CSIR laboratories. The R&D productivity of researchers can be improved through implementing the constructs of the proposed model of productivity. Research limitations/implications – The R&D productivity model can be adapted by the R&D laboratories to enhance researchers’ R&D involvement, increased R&D outputs and achieving self-sustenance in long run. Practical implications – The R&D laboratories can initiate exercises to explore the most relevant factors and measures to enhance R&D productivity of their researchers. The constructs of the model can function as a guideline to introduce the most preferable research policies in the laboratory for overall mutual growth of laboratory and the researchers. Originality/value – Hardly any studies have been found that have focused on finding the measures of enhancing R&D involvement of researchers and the influence of significant time-intensive jobs on researchers’ productivity. Keywords R&D productivity model, CSIR, Mandays-involvement, Non –R&D jobs Paper type Research pape

A PRECIOUS HERB - GMELINA ARBOREA LINN. W.S.R TO ITS MEDICINAL USES AND PHARMACOLOGICAL ACTIVITY

Traditional medicines play an important role in health services around the globe. About three quarter of the world population relies on plants and plant product for health care. Gmelina arborea Linn. an important medicinal plant is one of the most widely cultivated species of the family Verbenaceae. It is commonly known as Gambhari,  the term actually used by tribal people of Bihar. It is one of the herb mentioned in all ancient literature of Ayurveda in diseases like ulcer, diarrhoea, thirst, anaemia, leprosy, vaginal discharge, piles, fever and varieties of ailments. It is highly valued from the immemorial because of its vast medicinal properties. Gambhari is a fast growing deciduous tree occurring naturally throughout greater part of India at altitudes up to 1,500 meters. It is an essential component of Dashamula dravya (group of ten roots) and has been used for its valuable medicinal properties like Medhya (Intellect power), Keshya (Hair tonic) and Rasayana (Rejuvenator). Acharya Charaka mentioned Gambhari in Sothahara, Dahaprasamana, Virecanopaga mahakasaya and also explain its fruit as best among Rakta-Sangrahaka and Raktapittahara. The roots,  fruits and the leaves of Gambhari have great medicinal value therefore traditionally it was widely used as anthelmintic, antimicrobial, anti-diabetic, anti-aging, analgesic, diuretic, hepato-protective and antiepileptic agent. The present article provides all necessary information regarding its classical literature, general introduction, medicinal uses of its roots, leaves, flowers, fruit, bark, and pharmacological studies conducted till date

Aligning Individual and Organizational R&D Goals for Self-Sustainability: Investigating Preferences of Researchers in Selected CSIR-Laboratories, India

This paper intends to explore the measure for aligning the goals of researchers towards achieving organizational R&D targets. The paper also explores the significance and ordering of R&D outputs and the factors that influence generation of R&D outputs, from the perspective of researchers working in the Indian public sector organizations. Data was collected in five Indian R&D laboratories and Weighted Average Method; Spearman Correlation Coefficient and Rank Regression were utilized for the analysis. The findings indicated that various groups of researchers prefer to target different R&D outputs and not all the factors are considered as equally significant in influencing the generation of R&D outputs. Further, the R&D organization should include preferred real factors while policy making for achieving collaborative efforts towards fulfilling organizational objectives. The set of selected R&D outputs and influencing factors were also ordered according to the average rankings given by the researchers. The findings can help R&D managers to identify the expectations of the researchers and include their preferences in R&D Planning. The study could be extended to a larger dataset of researchers working in other government as well as private R&D organizations. Hardly any studies were found that explored the preferences of researchers with respect to R&D outputs and influencing factors with respect to the Indian public sector R&D laboratories. Author Accepted Manuscript (AAM) Version License Emerald allows authors to deposit their AAM under the Creative Commons Attribution Non-commercial International Licence 4.0 (CC BY-NC 4.0). To do this, the deposit must clearly state that the AAM is deposited under this licence and that any reuse is allowed in accordance with the terms outlined by the licence. To reuse the AAM for commercial purposes, permission should be sought by contacting [email protected]. For the sake of clarity, commercial usage would be considered as, but not limited to: o Copying or downloading AAMs for further distribution for a fee; o Any use of the AAM in conjunction with advertising; o Any use of the AAM by for promotional purposes by for-profit organisations; o Any use that would confer monetary reward, commercial gain or commercial exploitation. Final Published Version is available at: DOI (10.1108/IJPPM-12-2019-0556) Citation Kumari, B., Sahney, S. and Madhukar, A. (2021), "Aligning individual and organizational R&D goals for self-sustainability: investigating preferences of researchers in selected CSIR laboratories, India", International Journal of Productivity and Performance Management, Vol. ahead-of-print No. ahead-of-print. https://doi.org/10.1108/IJPPM-12-2019-055

Structural, dielectric, and optical studies of magnetoelectric Bi2Fe4O9

Multiferroic means the co-existence of two or more ferroic order property, such as ferroelectricity, ferromagnetism and/or ferroelasticity. Most of the mutiferroic materials have very low transition temperature but Bi2Fe4O9 have transition temperature which is near to the room temperature. Bi2Fe4O9 is a type II multiferroic, so it has very strong magnetoelectric coupling. Bi2Fe4O9 has a pentagonal symmetric structure. Bi2Fe4O9 was sintered at 850oC for 12 hours. Then characterizations were done to study different structural, dielectric and optical properties of Bi2Fe4O9

True broad ligament fibroid mimicking ovarian mass in a postmenopausal woman

Fibroids are benign smooth muscle tumors. Large fibroids are known to arise from the uterus, but occasionally from the broad ligament.  Here, we report a case of true broad ligament fibroid which is rare and difficult to diagnose in a 57 year old postmenopausal women with a large mass of 24 weeks size gravid uterus. Patient presented with pain lower abdomen and mass in abdomen with no other co-morbidity. This broad ligament fibroid was mimicking as ovarian tumor on ultrasonography and MRI as left ovary was not visualised separately, thus leading to diagnostic dilemma of ovarian malignancy. Mass resection with total abdominal hysterectomy and bilateral salpingo-oopherectomy was performed. No local or distant metastasis observed, and Histopathology showed true broad ligament fibroid of left side weighing 3.57 kilograms

A COMPREHENSIVE REVIEW OF WOODFORDIA FLORIBUNDA SALISB.

Indian medicinal plants are the essence of Ayurveda and Ayurvedic treatments. When used judicially and clocking with the basic principles they produce miraculous effects. Fire flamed Bush (Woodfordia floribunda salisb), commonly called as Dhavari, Dhataki, belongs to the family Lythraceae. It is an important medicinal plant of tropical and subtropical India. Dhataki is a deciduous shrub, usually with a much fluted stem, spreading branches, 1-3 m high, rarely up to 7 m, commonly occurring throughout North India, ascending to an altitude of 1,500 m in the Himalayas, but rather scarce in South India. Acharya Charak quoted it among the fermenting agents (Asava yoni) and described under Purisasangrahniya, Mutravirajaniya and Sandhaniya group of drugs. The reported pharmacological activities of Woodfordia floribunda salisb. are antitumor activity, DNA inhibitory activity, immunomodulatory activity, antioxidant activities, antihyperglycemic activity, anti- inflammatory and analgesic properties, antimicrobial activity, hepatoprotective activity, etc. Dhataki is one of the major ingredient of many important formulations used in Ayurvedic system of medicine such as Dhatakyadi taila, Dhatakyadi curna, Pusyanuga curna, Brhat Gangadhara curna, Arvindasava. So this review paper is an attempt of the author to provide details of this medicinal plant Dhataki about its classical references, synonyms, botanical description, phytochemical and pharmacological activity and classical medicinal uses

Formulation of biocomposite of ultrasonication mediated cellulose and lignin nanofibers for biomedical applications

135-142Current study deals with the synthesis of bio-composites using nanofibres of lignin and cellulose embedded in pectin. Nanofibres of lignin and cellulose were generated through ultrasonication in varying doses and polymerized with pectin in order to formulate biocomposite through atomic transfer radical polymerization technique. The average size of the cellulose and lignin nanofibers formed were of 7.38 nm and 262.1 nm, respectively on ultra-sonicating it (50% amplitude, 2 sec on and off pulses at 30 ºC) for 15 min. Biocomposite was characterized through TGA analysis, which shows thermal degradation start after 100 ºC and at 761ºC about 60% of weight loss was observed, which proved its high thermostability. Scanning electron microscopy study concluded that surface of the biocomposite was smooth and homogenous. The structural analysis using FTIR illustrated ester bond formation between the hydroxyl group of lignin and cellulose with the carboxyl groups of pectin molecules while polymerization, which imparted it thermal stability and strength. On further analysis, biocomposite has shown distinct antioxidant property, negligible cell cytotoxicity and started auto- degenerate just after 15 min in aqueous medium, therefore this can be explored in biomedical and pharmaceutical industries for controlled drug delivery and as drug carrier

Formulation of biocomposite of ultrasonication mediated cellulose and lignin nanofibers for biomedical applications

 Current study deals with the synthesis of bio-composites using nanofibres of lignin and cellulose embedded in pectin. Nanofibres of lignin and cellulose were generated through ultrasonication in varying doses and polymerized with pectin in order to formulate biocomposite through atomic transfer radical polymerization technique. The average size of the cellulose and lignin nanofibers formed were of 7.38 nm and 262.1 nm, respectively on ultra-sonicating it (50% amplitude, 2 sec on and off pulses at 30 ºC) for 15 min. Biocomposite was characterized through TGA analysis, which shows thermal degradation start after 100 ºC and at 761ºC about 60% of weight loss was observed, which proved its high thermostability. Scanning electron microscopy study concluded that surface of the biocomposite was smooth and homogenous. The structural analysis using FTIR illustrated ester bond formation between the hydroxyl group of lignin and cellulose with the carboxyl groups of pectin molecules while polymerization, which imparted it thermal stability and strength. On further analysis, biocomposite has shown distinct antioxidant property, negligible cell cytotoxicity and started auto- degenerate just after 15 min in aqueous medium, therefore this can be explored in biomedical and pharmaceutical industries for controlled drug delivery and as drug carrier.