2,947 research outputs found
Comparison of Clinical Manifestations between Patients with Ocular Myasthenia Gravis and Generalized Myasthenia Gravis
PURPOSE: To compare the clinical manifestations between patients with ocular myasthenia gravis and those with generalized myasthenia gravis (MG). METHODS: The medical records of 71 patients diagnosed with MG between January 1995 and December 2007 were reviewed. Demographics, sensitivities of diagnostic methods, the presence of systemic autoimmune diseases, ophthalmic complications caused by MG, and treatments were evaluated and compared. RESULTS: Fourteen patients (20%) were diagnosed with ocular MG and 57 patients (80%) with generalized MG. Sensitivities of anti-acetylcholine receptor antibody and repetitive nerve stimulation tests were significantly higher in the generalized MG group (84%, 89%) compared to those in the ocular MG group (50%, 54%) (p = 0.011, p = 0.008). The sensitivity of the neostigmine test was the highest in both groups (98% of generalized MG, 79% of ocular MG), and the difference between the two groups was borderline significant (p = 0.058). The most common symptoms were ptosis and diplopia, and both groups presented with pain, blurred vision, and tearing. Systemic autoimmune disease was more prominent in the generalized MG group (21%) than in the ocular MG group (14%), and steroid therapy was used more frequently in the generalized MG group (82%) than in the ocular MG group (57%). Ophthalmic complications associated with long-term steroid treatment were more profound in the generalized MG (30%) compared to those of the ocular MG (21%). CONCLUSIONS: The generalized MG group was associated with higher sensitivities to diagnostic tests, more systemic steroid use, higher ophthalmic complications caused by systemic autoimmune disease, and long-term steroid treatment compared to those of the ocular MG groupope
MOF-Derived Cu@Cu2O Nanocatalyst for Oxygen Reduction Reaction and Cycloaddition Reaction
Research on the synthesis of nanomaterials using metal-organic frameworks (MOFs), which are characterized by multi-functionality and porosity, as precursors have been accomplished through various synthetic approaches. In this study, copper and copper oxide nanoparticles were fabricated within 30 min by a simple and rapid method involving the reduction of a copper(II)-containing MOF with sodium borohydride solution at room temperature. The obtained nanoparticles consist of a copper core and a copper oxide shell exhibited catalytic activity in the oxygen reduction reaction. The as-synthesized Cu@Cu2O core-shell nanocatalyst exhibited an enhanced limit current density as well as onset potential in the electrocatalytic oxygen reduction reaction (ORR). Moreover, the nanoparticles exhibited good catalytic activity in the Huisgen cycloaddition of various substituted azides and alkynes under mild reaction conditions
Edit-A-Video: Single Video Editing with Object-Aware Consistency
Despite the fact that text-to-video (TTV) model has recently achieved
remarkable success, there have been few approaches on TTV for its extension to
video editing. Motivated by approaches on TTV models adapting from
diffusion-based text-to-image (TTI) models, we suggest the video editing
framework given only a pretrained TTI model and a single pair,
which we term Edit-A-Video. The framework consists of two stages: (1) inflating
the 2D model into the 3D model by appending temporal modules and tuning on the
source video (2) inverting the source video into the noise and editing with
target text prompt and attention map injection. Each stage enables the temporal
modeling and preservation of semantic attributes of the source video. One of
the key challenges for video editing include a background inconsistency
problem, where the regions not included for the edit suffer from undesirable
and inconsistent temporal alterations. To mitigate this issue, we also
introduce a novel mask blending method, termed as sparse-causal blending (SC
Blending). We improve previous mask blending methods to reflect the temporal
consistency so that the area where the editing is applied exhibits smooth
transition while also achieving spatio-temporal consistency of the unedited
regions. We present extensive experimental results over various types of text
and videos, and demonstrate the superiority of the proposed method compared to
baselines in terms of background consistency, text alignment, and video editing
quality
A STUDY ON THE ESTIMATION METHOD OF THE FORM FACTOR FOR A FULL-SCALE SHIP
In this study, a prediction method of the form factor for a full-scale ship is suggested to minimize the power prediction error from a small model ship. Numerical simulations were carried out at various Reynolds numbers from a small model to a full-scale ship. The variation of the form factors was investigated from the results of the numerical simulation according to the Reynolds numbers. In addition, the results from the numerical simulations and experimental data of the geosim models were utilized to drive the correlation line and predict the form factor of a full-scale ship. The correlation line was applied to predict the effective power and the delivered power of a full-scale ship. As a result, the developed prediction method confirmed the possibility of predicting the power reliably from experiments using a small model
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