1,067 research outputs found
The effect of gluon condensate on holographic heavy quark potential
The gluon condensate is very sensitive to the QCD deconfinement transition
since its value changes drastically with the deconfinement transition. We
calculate the gluon condensate dependence of the heavy quark potential in
AdS/CFT to study how the property of the heavy quarkonium is affected by a
relic of the deconfinement transition. We observe that the heavy quark
potential becomes deeper as the value of the gluon condensate decreases. We
interpret this as a dropping of the heavy quarkonium mass just above the
deconfinement transition, which is similar to the results obtained from QCD sum
rule and from a bottom-up AdS/QCD model.Comment: 16 pages, 6 figures, typos corrected, references adde
Quasi-Eigenstate Evolution in Open Chaotic Billiards
We experimentally studied evolution of quasi-eigenmodes as classical dynamics
undergoing a transition from being regular to chaotic in open quantum
billiards. In a deformation-variable microcavity we traced all high-Q cavity
modes in a wide range of frequency as the cavity deformation increased. By
employing an internal parameter we were able to obtain a mode-dynamics diagram
at a given deformation, showing avoided crossings between different mode
groups, and could directly observe the coupling strengths induced by ray chaos
among encountering modes. We also show that the observed mode-dynamics diagrams
reflect the underlying classical ray dynamics in the phase space.Comment: 4 pages, 4 figure
Development of deformation-tunable quadrupolar microcavity
We have developed a technique for realizing a two-dimensional quadrupolar
microcavity with its deformation variable from 0% to 20% continuously. We
employed a microjet ejected from a noncircular orifice in order to generate a
stationary column with modulated quadrupolar deformation in its cross section.
Wavelength red shifts of low-order cavity modes due to shape deformation were
measured and were found to be in good agreement with the wave calculation for
the same deformation, indicating the observed deformation is quadrupolar in
nature.Comment: 7 pages, 6 figures, intended for Rev. Sci. Instu
Chaos-assisted nonresonant optical pumping of quadrupole-deformed microlasers
Efficient nonresonant optical pumping of a high-Q scar mode in a
two-dimensional quadrupole-deformed microlaser has been demonstrated based on
ray and wave chaos. Three-fold enhancement in the lasing power was achieved at
a properly chosen pumping angle. The experimental result is consistent with ray
tracing and wave overlap integral calculations.Comment: 3 pages, 5 figure
Genome-scale metabolic model of the fission yeast Schizosaccharomyces pombe and the reconciliation of in silico/in vivo mutant growth
<p>Abstract</p> <p>Background</p> <p>Over the last decade, the genome-scale metabolic models have been playing increasingly important roles in elucidating metabolic characteristics of biological systems for a wide range of applications including, but not limited to, system-wide identification of drug targets and production of high value biochemical compounds. However, these genome-scale metabolic models must be able to first predict known <it>in vivo</it> phenotypes before it is applied towards these applications with high confidence. One benchmark for measuring the <it>in silico</it> capability in predicting <it>in vivo</it> phenotypes is the use of single-gene mutant libraries to measure the accuracy of knockout simulations in predicting mutant growth phenotypes.</p> <p>Results</p> <p>Here we employed a systematic and iterative process, designated as Reconciling <it>In silico/in vivo</it> mutaNt Growth (RING), to settle discrepancies between <it>in silico</it> prediction and <it>in vivo</it> observations to a newly reconstructed genome-scale metabolic model of the fission yeast, <it>Schizosaccharomyces pombe</it>, SpoMBEL1693. The predictive capabilities of the genome-scale metabolic model in predicting single-gene mutant growth phenotypes were measured against the single-gene mutant library of <it>S. pombe</it>. The use of RING resulted in improving the overall predictive capability of SpoMBEL1693 by 21.5%, from 61.2% to 82.7% (92.5% of the negative predictions matched the observed growth phenotype and 79.7% the positive predictions matched the observed growth phenotype).</p> <p>Conclusion</p> <p>This study presents validation and refinement of a newly reconstructed metabolic model of the yeast <it>S. pombe</it>, through improving the metabolic modelโs predictive capabilities by reconciling the <it>in silico</it> predicted growth phenotypes of single-gene knockout mutants, with experimental <it>in vivo</it> growth data.</p
Differential Diagnosis for Chronic Diarrhea: Are Multiple Random Biopsies with Colonoscopy Mandatory?
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