200 research outputs found

    The Effectiveness Of Pss (Plays, Stories, Songs) Method In Learning English AS A Foreign Language: An Experimental Study At State Madrasah Ibtidaiyah 1 Of Palembang

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    The purpose of this study is to determine the effectiveness of the PSS method in teaching English as a foreign language at State Madrasah Ibtidaiyah 1 of Palembang. This study is also to determine the effect of PSS method in improving student learning outcomes.This research is a quantitative researchusingthe classes that already exist as a group, both for the experimental class and the control class, which is estimated at the same condition. The experimental study class consisted of 36 students and a control class also consists of 36 students.The result of the analysis show that the experimental class of 36 students on average score of 4.5 on the learning outcomes of pre-test and 5.97 at post-test. While the control class scored on average of 4.91 on the learning outcomes of the pre-test and 4.97 at post-test. The results of the SPSS hypothesis analysis that has been done in the paired samples t-test show that the mean of the experimental group is -1.472 with standard deviation 2.131. And t value is -4.145, while significant (2-tailed) of 0.000˂0.05. It can be concluded that rejected Ho, and can be said that there is a significant difference of students\u27 achievement before and after the application of PSS method

    Transcatheter Closure of Atrial Septal Defect and the Effects on Right Ventricular Function; Strain and Strain Rate Echocardiography

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    29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400409Turkish Soc Cardio

    The Use of Total Artificial Heart With Example of Cases for End-Stage Heart Failure Therapy

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    29th Turkish Cardiology Congress of the Turkish-Society-of-Cardiology (TSC) with International Participation -- OCT 26-29, 2013 -- Antalya, TURKEYWOS: 000329858400098Turkish Soc Cardio

    Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

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    Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure < 100 mmHg (n = 1127), estimated glomerular filtration rate < 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

    Genetic, cellular and molecular mechanisms of pulmonary arterial hypertension

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    WOS: 000282728600004PubMed ID: 20819762Pulmonary arterial hypertension (PAH) is an uncommon disorder that may be hereditable, idiopathic or associated with conditions like drug exposure, connective tissue disease, HIV infection or congenital heart disease. Familial disease are usually due to mutations in the bone morphogenic protein receptor type 2 (BMPR2), activin-like kinase-type 1 (ALK1) and endoglin (ENG). Functional and structural changes in the pulmonary vasculature lead to increased pulmonary vascular resistance. Vascular remodeling involves endothelial dysfunction, activation of fibroblasts and smooth muscle cells and recruitment of circulating progenitor cells. Vasoconstriction has also been shown to affect the remodeling process. Genetics, cellular and molecular basis of PAH are discussed in the paper. (Anadolu Kardiyol Derg 2010; 10: Suppl 1; 9-13

    Epicardial fat: More than an adipose tissue

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